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Alcoholism and Genetics

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Alcoholism and Genetics Alcoholism has an affect everyone one way or another. It is a complex disease that not only affects the alcoholic but it also affects their families and loved ones. Alcoholism is considered an addition, which can be contributed to a range of genetic, social, and environmental influences. Historically, alcoholism was blamed on one’s character; it was seen as a flaw and/or weakness (Perry). “Alcoholism affected approximately 4.65 percent of the U.S. population in 2001–2002, producing severe economic, social, and medical ramifications” (Sloan, Sayarath and Moore). As many know, genetics plays a strong role in the component of alcoholism. As more genes are linked to the development of an alcohol addition, the finding will be proven useful in developing the necessary tools to better identify those who are at risk (Perry). For the last 25 years, a variety of human studies have supported the “theory of a genetic component in the susceptibility to alcoholism” (Begleiter). Researchers now estimated that between 50 and 60 percent of alcoholism risk is determined by genetics (Sloan, Sayarath and Moore). “It has sparked numerous linkage and association studies to include, investigating the roles of chromosomal regions and genetic variants in determining alcoholism susceptibility” (Sloan, Sayarath and Moore). There have been multiple studies to identify the gene that could potentially lead to a higher risk for alcoholism. For example, family studies have been conducted to measure the frequency of alcoholism as well as related conditions consistently found that “biological relatives of people who abused or were dependent on alcohol were at a significant risk of developing the disorder themselves” (Begleiter). However, “the complex etiology of alcoholism lends itself to further investigation that takes into account the multiple layers of

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