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Bicarbonate Infusion

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The title of the article is “Bicarbonate Infusion and PH Clamp Moderately Reduce Hyperventilation During Ramp Exercise In Humans.” The authors of this article are Francois Pe´ronnet, Tim Meyer, Bernard Aguilaniu, Carl-E´ tienne Juneau, Oliver Faude, and Wilfried Kindermann. The purpose of this study was to find whether bicarbonate infusion and pH clamp moderately reduce hyperventilation during ramp exercise in humans. The study was completely focused upon males; no females were tested during the experiment. “Results from the present experiment confirm that the increase in plasma H concentration contributes to the control of hyperventilation at high workloads. This stimulus could be responsible for at least 30% of the disproportionate increase in VE observed in this situation and when suppressed by bicarbonate infusion was not fully compensated by the remaining putative control mechanisms of hyperventilation”(Pe´ronnet F, Meyer T, Aguilaniu B, Juneau CE´ , Faude O, Kindermann W). This result means when you add the plasma H to your body before a workout it helps control your hyperventilation during the exercise. This study relates to what we have talked in class about the “buffer system” in how in the …show more content…
This heavy breathing is to supply the oxygen required by the increased metabolism in our body. We must breathe more oxygen to keep our muscles working properly and so that we won’t get cramps. When we exercise too profusely, metabolic acidosis occurs. Metabolic acidosis is when there is too much acid in the body fluid. In the study, the male subjects were required to do 2 exercises per subject. The workload heightened between the exercises; the control exercise was the least difficult of all. Sterile isotonic saline was also really important when they conducted the experiment. The saline solution was used as IV drips for rehydration, this prevented excessive fluid redistribution to the blood

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