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Bowman's Capsule

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The overall functions of the kidney include secreting hormones into circulation, excreting waste products, water/electrolyte balancing and acid/base balancing. The nephron is the functional unit of the kidney with the head of which is the Bowman’s capsule. After substances enter this area they will go through the proximal tubule to the Loop of Henle which has ascending and descending areas. Through those filtered substances move to the distal convoluted tubule to the collecting duct where they will be passed to the bladder as waste.

The Bowman’s capsule and glomerulus make up the renal corpuscle while on the outside the juxtaglomerular complex is made up of Macula Densa, Mesangial and Granular Cells. In Bowman’s Capsule an afferent arteriole brings in blood to the glomeruli and exits the efferent arteriole. Podocytes wrap around the capillaries which help with filtrations while the Mesangial cells which are important in contraction and altering …show more content…
The liver starts by producing angiotensinogen and the kidney responds by secreting renin which react by creating Angiotensin I. when Angiotensin I reaches the lungs they release ACE or Angiotensin converting enzyme when ACE and angiotensin I react they create Angiotensin II, which works on the level of the kidneys and adrenal glands. When Angiotensin II reacts with the adrenal glands they secrete Aldosterone which regulates BP by increasing the reabsorption of Na which increase fluid volume thus increasing BP. Secondly Aldosterone decreases K+ via urine. When Angiotensin II reacts on the kidneys it cause vasoconstriction on the arterioles which also increases BP. Renal Clearance is Cx = UxV/Px = volume of plasma from which the substance is completely cleared per unit time. Cx = clearance of X (mL/min); Ux = urine concentration of X (eg, mg/mL); Px = plasma concentration of X (eg, mg/mL); V = urine ow rate

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