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Cellular Respiration In Stem Cell Research

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Significant evidence relating to the cause of cancer has been discovered by professionals during the decades spent researching. The cause of cancer relates to the process known as cellular respiration. Cellular respiration is a four step process that ultimately oxidizes glucose into ATP. The first step occurs in the cytoplasm and is called glycolysis. This stage is where glucose is broken down into pyruvate and two ATP. This pyruvate moves into the mitochondrial matrix where it is further oxidized into acetyl CoA before moving into the citric acid cycle to become NADH and FADH2. The final step occurs in the inner membrane space and is known as the electron transport chain. NADH and FADH2 donate electrons which will be shuttled between the complexes. Once the fourth complex is powered, the electron is released and accepted by oxygen. The proton motor force powers the ATP synthase by forcing hydrogen to flow through it allowing approximately 32 ATP to be synthesized. …show more content…
The only stage of respiration that is anaerobic is glycolysis. If pyruvate is unable to be oxidized, fermentation occurs. In humans, fermentation results in lactic acid and only 2 ATP forming. This is an inefficient way of synthesizing energy. Biochemist Otto Warburg compares respiration and fermentation to two engines being fueled by either complete combustion or incomplete combustion. Respiration is the complete combustion because all four stages are conducted while fermentation is the incomplete combustion because instead of going through all of the stages of cellular respiration, only glycolysis

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