Cholera has been around for many ages. During the 19th century, cholera spread across the world from its original location in the Ganges delta in India. Six pandemics killed millions of people across all continents. The current pandemic started in South Asia in 1961, and reached Africa in 1971 and North and South America in 1991. The first cholera pandemic occurred in the Bengal region of India starting in 1817 and lasting until 1824. Cholera is now epidemic in many countries. Cholera is a bacterial disease that infects the small intestine and causes diarrhea and dehydration. The bacteria was isolated in 1854 by Italian anatomist Filippo Pacini, but its exact nature and his results were not widely known. Spanish physician Jaume Ferran i Clua developed a cholera vaccine in 1885, the first vaccine to immunize humans against a bacterial disease. You lose almost all of your water which causes you to become dehydrated. Treatments are to get fluids into your body by drinking a mixture of water, sugar, and salt and it helps keep it in your system. You can buy this solution and its called Gatorade. About 100 million bacteria must typically be ingested to cause cholera in a normal healthy adult. Children are also more susceptible, with two- to four-year-olds having the highest rates of infection. Cholera is typically transmitted by either contaminated food or water. In developed countries seafood is the usual cause, while in third world countries it is more often water. Most cholera cases in developed countries are a result of transmission by food. 3-5 million people have been infected with Cholera and over 100,000 people have been killed because of it. Anyone who lives with inadequate water treatments are in danger of getting this. It is found in Haiti and China today. Cholera started off as Hog Cholera and evolved into human. Ways to prevent this disease are to drink clean water and eat foods you’ve cooked and that are still hot. Cholera is an acute diarrhoeal disease that can kill within hours if its not treated. Symptoms usually start about a half a day to five days after intaking of the bacteria. About 75% of people infected with Cholera do not develop symptoms until its too late. Robert Allan Phillips, working at the US Naval Medical Research Unit Two in Southeast Asia, evaluated the disease using modern laboratory chemistry techniques and developed a protocol for rehydration. Up to 80% of cases can successfully be treated by oral rehydration which is the consumption of salt, sugar, and water. An untreated person with cholera may produce 3 to 5 gallons of diarrhea a day. Cholera has been nicknamed the "blue death" because a person's skin may turn bluish-gray from extreme loss of body fluid. Newer strains have been detected in several parts of Asia and Africa. Observations suggest that these strains cause more severe cholera with higher fatality rates.