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Chronic Periodontitis Case Study

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Chronic periodontitis (CP) is initiated by the sub-gingival biofilm but the progression of destructive disease appears to be dependent upon an abnormal host response to those organisms. The presence of microorganisms is a crucial factor in inflammatory periodontal disease, but the progression of the disease is related to host-based risk factors. Oxidative stress and antioxidants play an important role in the pathogenesis of inflammatory disease, including periodontitis. Cigarette smoking is well known be a measure known problem various cell disorder including periodontal inflammation. Smoking has been identify as a most modifiable risk factor for peridontitis, followed by dental biofilm1,2 .Abundant cross-sectional data support the adverse relationship between smoking and periodontal diseases. …show more content…
A strong dose response relationship between the amount smoked and the severity of periodontal destruction has also been shown, further supporting the role of smoking as a risk factor for periodontitis6, 7 , 8. Smokers are almost four times more likely to have severe periodontitis than non-smokers9 . However, the exact mechanisms by which smoking exerts its deleterious effects on periodontium remain unclear. One potential mechanism is through tissue damage mediated by oxidative species originating from tobacco smoke and tobacco induced inflammation, in addition to the direct cigarette smoke mediated depletion of antioxidants. It has been claimed that there is significant decrease in the concentration of …show more content…
2009). Periodontitis is a multifactorial irreversible and cumulative condition, initiated and propagated by bacteria and host factors (Kinane 2001). More than 500 different bacterial species are able to

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