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Helicobacter Pylori Research Paper

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Helicobacter pylori is a Gram negative, enveloped, spiral shaped (curved rod) bacterium that colonizes the stomach of humans[1]. The spiral shape, along with multiple flagella, allows for the bacterium to be very motile in the stomach, using a corkscrew motion to achieve motility[2]. H.pylori measures at 2 to 4 μm length wise, and 0.5 to 1 μm in width, and is slow growing, making is difficult to culture in a lab[1][2]. The cell structure of H.pylori is typical of other Gram negative bacteria, consisting of peptidoglycan and an outer membrane of phospholipids and LPS This bacterium prefers a microaerophilic environment, with the ideal oxygen level around 2-5%, as well as 5-10% carbon dioxide level and high humidity [1]. H.pylori grows best within the temperature range of 34-40 degrees celsius, with the optimal temperature being 37 degrees celsius[1], all of these factors make the environment of the human stomach to be perfectly suited for H.pylori growth. …show more content…
The Transmission of H.pylori is still largely unknown[1]. It is mainly believed that the transmission of H.pylori is human to human, through oral-fecal or oral-oral route[1]. H.pylori may use vehicle transmission through water contaminated with fecal matter to infect human [1], which would explain the higher prevalence of infection in developing countries, as those countries tend to have poor water sanitation

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