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Herbal Medicinal Plants

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Background of the Study Folklore medicines have been used as treatment to a variety of disease and ailments, not only in developing countries but developed countries as well. Most drugs used today came from various plant extracts, specifically, herbal medicinal plants. Natural products such as medicinal plants would be beneficial to the industry for its low-cost and source of potential therapeutic aid.
Recent studies have shown that majority of these herbal plants exhibit pharmacological activities and no side effects were seen during the process. However, assessment of the biological activities through clinical trials exhibited by plants is lacking. Thus, analyzation of its composition and more information is greatly needed by the research …show more content…
Molina (2015) cited that M. pudica has antimicrobial properties with its growth inhibition on the bacteria Bacillus subtilis, Staphyloccocus aureus, and Candida Albicans. Antimicrobial and antioxidant properties of makahiya were also noted by Racadio (2016). The weed A. conyzoides was also found to have pharmacological activities that include analgesic activity, antimicrobial activity, anti-inflammatory activity, and radical scavenging activity (Singh et al., 2013). In the Comparative phytochemical analysis of aerial parts of A. procumbeans, F. dichotoma, S. sponteneum, S. nigraand T. angustifolia conducted by Padalia & Chanda (2015), S. spontaneum possessed antidiarrhoeal, antioxidant, antilithiatic and antimicrobial properties. The plants were proven to have these biological activities through phytochemical screening. Due to these assessments, it could be inferred that these plants could have the possibility to produce useful drugs as well as it can give benefit the pharmaceutical industry in the …show more content…
pudica, S. spontaneum, and A. conyzoides are suggested to have potential toxic bioactive compounds reported by different studies. Adebayo et al. (2010) stated that A. conyzoides extracts exhibited cytotoxic activities against A-549 and P-388 cancer cells. Tran et al. (2003) noted that the aqueous, methanolic, and ethanolic extracts of M. pudica exhibited antiplasmodial activity against P. falciparum, which is known parasite causing malaria. Also, the phytochemical analysis of Padalia & Chanda (2015) suggests cytotoxic activities for S. spontaneum.
Statement of the Problem This study aims to determine the cytotoxicity of the methanolic extracts of Mimosa pudica, Ageratum conyzoides and Saccharum spontaneum.
The following questions will be answered through this study:
1. Are M. pudica, A. conyzoides and S. spontaneum methanolic extracts toxic to the brine shrimp nauplii?
2. At which concentration of the methanolic extracts of M. pudica, A. conyzoides and S. spontaneum yields the highest mortality rate?
3. At which concentration of the three plant extracts yields the LC50 values?
Scope and Delimitations
This study focuses on common weeds Mimosa pudica, Saccharum spontaneum, and Ageratum conyzoides that are found in the Philippines. The plant samples were gathered within the vicinity of Quezon City. It aims to evaluate the cytotoxic activities of the methanolic extracts of said plants in vitro.
Significance of the

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