...Clinically Induced Hypothermia in the Management of Severe Head Injury: A Review of the Evidence PAGE 1. Title Page 2. Acknowledgements 3. Contents 4-5. Abstract 6-7. Introduction 8-11. Methods 9. i) Inclusion & Exclusion Criteria 10. ii) Limitations of Search 11. iii) Critical Framework 12-26. Critical Review of the Data 13. i) Study Aims & Design 19. ii) Sampling & Controls 25. iii) Results 27-36. Discussion 32. i) Implications for Practice 37-41. References 42. Appendix 1) – The Four Stages of Research 43. Appendix 2) – Database Search (Hard Copy Only) 44-49. Appendix 3) – Example (1) Using the CASP Framework 50-55. Appendix 3) – Example (2) Using the CASP Framework 56. Appendix 4) – Summary of Studies (Hard Copy Only) 57. Appendix 5) – Intracranial Pressures 58. Appendix 6) – Type 1 & 2 Errors 59. Appendix 7) – The Hawthorne Effect 60. Appendix 8) – The Glasgow Outcome Score 61. Appendix 9) – The Hierarchy of Evidence ABSTRACT Medically induced hypothermia has been used as a neuro-protector to try and limit the consequences of severe brain injury for more than fifty years but it is only recently that its effectiveness has been assessed using randomised controlled trials. Under certain circumstances clinically induced hypothermia has already been proven to be beneficial by providing a degree of neuroprotection in post-cardiac arrest patients. As such it has recently...
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...microscopy/microscope SFM scanning force microscopy/microscope SICM scanning ion conductance microscopy/microscope SPM scanning probe microscopy/microscope STM scanning tunneling microscopy/microscope A new journal, Probe Microscopy, was launched in 1997 as a forum specifically devoted to the science and technology of SPM. AFM and SFM have been also newsworthy items in Science and Nature in the past year [14••,15•–17•,18••,19]. An introduction to AFM is covered well in a recent issue of Current Opinion in Chemical Biology, which describes and illustrates the design and mode of operation of AFM [4••]. The AFM images sample surfaces by raster-scanning a sharp tip back and forth over the surface. The tip is on a cantilever that responds to height changes on the sample surface in a way that generates a topographical map of the surface. We build on this excellent introduction by presenting some of the many advances in SPM that have occurred since that review was written. (The accompanying images are from AFM research in the authors’ lab). Atomic force microscopy imaging Proteins Entropic brush...
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...Personal: 0812782540 E-Mail Address - Work: mohamem@telkom.co.za E-Mail Address - Personal: Roocshanam@gmail.com Personal Information Surname: Mohamed First Name(s): Roocshana Known as: Shana ID Number: 7604250250083 *Race: Coloured *Gender: Female Driver's License: C1 Disability: Not Indicated HEALTH: Excellent Address: 1090 Camelia Court Westbury Johannesburg 2093 Languages Afrikaans-Speak Afrikaans-Read Afrikaans-Write English-Speak English-Read English-Write Secondary Education School: Westbury senior Secondary Highest Standard / Grade: GRADE 12 (STANDARD 10/MATRIC) Year of Completion: 1994 Subjects Passed: Afrikaans (HG) English (HG) Geography (HG) Biology (HG) Mathematics (SG) Science (SG) Tertiary Education Studies Completed 1. Institution: Varsity College Qualification: Management Accounting and Finance (Diploma) Year of Graduation: 1998 2. Institution: Atcor UK Qualification: Accounting Technician (Diploma) Year of Graduation: 2008 Major Subjects: Financial Accounting Cost accounting Taxation Studies in Progress 1. Institution: UNISA Qualification to be obtained: Administration Management (Financial) Expected Year of Graduation: 2014 Major Subjects: Administration Management...
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...ADMINISTRATION UNDER THE GUIDANCE OF INTERNAL GUIDE EXTERNAL GUIDE Prof. KALYANRAO MR.NIKHIL SHESAPPA Dept. of MBA Senior manager HGS Department of MBA Guru Nanak Dev Engineering College, Bidar July 2015 TALENT ACQUISITION HINDUJA GLOBAL SOLUTION GURU NANAK DEV ENGINEERING COLLEGE, BIDAR “A Study on Talent acquisition” ON PROJECT REPORT ON Submitted By N.Pallavi MBA IV SEMESTER USN-3GN13MBA20 Page 2 TALENT ACQUISITION HINDUJA GLOBAL...
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...Minex Introducing itself as one of the pioneers, Minex organization is based in India. Minex is an ISO 9001-2008 certified company serving Aluminum, Iron & Steel Industries & Non-Ferrous Industries for 30 years. The company is in operation since 1984 and has 3 operating plants in Central India, in the vicinity of Nagpur. In the past decade, Minex has emerged as a benchmark in providing total alloying solutions making it a $100 million company. The following products are regularly being used by reputed foundry industries: IRON FOUNDRIES: Ferro Silicon Magnesium Alloys for S.G. Iron production. Barium, Strontium, Calcium and Zirconium based inoculants. Nickel Magnesium Alloys. Rare Earth and Mischmetal Cored wires for S.G.Iron production, inoculating wires of various specifications for S.G. Iron production.Minex Wire Injection system for injection of Ferro Silico Magnesium cored wires and Inoculants cored wires. STEEL FOUNDRIES: Ferro, Aluminum Ferro, Silico, Calcium Ferro, Titanium Ferro, & Zirconium Cored Wires. ALUMINUM FOUNDRIES: Titanium, Boron, Aluminum, Aluminum-Boron, Iron Tablets. Aluminum-Chromium, Aluminum-Strontium, Aluminum-Iron Cored Wire Injection System. In the field of Cored Wire Feeder and Cored Wire, Minex is pioneer in this part of the world, having introduced this technology during the Eighties, initially with Wire Feeder and Metallurgical Cored Wires. Minex has installed, provided technological support and evolved Wire Injection...
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...subsidies. Research data by the Nippon Research center (2011-2012) suggests that most Japanese citizens (~88%) do not purchase whale meat (Mulvaney 2013). Moreover, ~47% tend to oppose the use of public money to fund whaling (Mulvaney 2013). Notably, current research polls show that Japanese students are actually in favor of school meat lunches (Bowett 2009). There appears to be a disconnect between the meat market, whaling funding, and the amount the government actually spends to support whaling. If there was a mandatory education class in schools, rather than pushing for whale meat school lunches, we could see a turnaround on the...
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...Running Head: THE HEALTH BENEFITS OF MEDITAION The Health Benefits of Meditation Article Critique Part two Paper Rasheedah Long Grand Canyon University NSG 325: Evidence Based Practice 03/30/2015 The purpose of composing this paper is to review one article that supports the PICOT statement. This paper will be written as an essay and will scrutinize major components of the study such as the introduction, the review of literature, the methods used, the findings, and lastly the discussion. This paper will provide an analytical view of the chosen article, determining the applicability of the findings, the clinical importance, the validity and the reliability of the issue addressed in the article. There are many different types of mediation practices. Transcendental meditation and mindfulness based stress reduction meditation are two of the most commonly researched. Meditation is now widely accepted into mainstream and is being used as a way for maintaining health and wellness. Several medical and rehabilitation facilities have proved meditation to be a safe and effective tool for treating: “stress, fatigue, depression, anxiety, fibromyalgia, hypertension, rheumatoid arthritis, diabetes, tinnitus, congestive heart failure, general pain, as well as many other health ailments. (Natural Medicine Database, 2014) Article Introduction The introduction to the study was clear and concise. It clearly identified what the researchers were looking to establish. The introduction...
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...Glucose Homeostasis Control of Mammalian Oestrus Plant Responses The Genetic Code Protein Synthesis Gene Mutations Stem Cells Control of Gene Expression Biotechnology DNA sequencing Southern Blot In vivo cloning Genetically Modified Organisms Gene Therapy Genetic Screening and Counselling 2 4 6 0 14 17 24 28 30 33 34 38 42 44 48 50 54 57 63 66 71 76 80 85 89 92 Molecular Genetics These notes may be used freely by A level biology students and teachers, and they may be copied and edited. Please do not use these materials for commercial purposes. I would be interested to hear of any comments and corrections. Neil C Millar (nmillar@ntlworld.co.uk) Head of Biology, Heckmondwike Grammar School High Street, Heckmondwike, WF16 0AH Jan 2010 HGS Biology A-level notes NCM 8/09 A2 Biology Unit 5 page 2 Biology Unit 5 Specification Control Systems Organisms increase their chance of survival by responding to changes in their environment. The Nerve Impulse The structure of a myelinated motor neurone. The establishment of a resting potential in terms of differential membrane permeability, electrochemical gradients and the movement of sodium and potassium ions. Changes in membrane permeability lead to depolarisation and the generation of an action potential. The all-or-nothing principle. The passage of an action potential along nonmyelinated and myelinated axons, resulting in nerve impulses. The nature and importance of the refractory period in producing discrete impulses....
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...Research on Butterfly Theorem Butterfly Theorem is one of the most appealing problems in the classic Euclidean plane geometry. The name of Butterfly Theorem is named very straightforward that the figure of Theorem just likes a butterfly. Over the last two hundreds, there are lots of research achievements about Butterfly Theorem that arouses many different mathematicians’ interests. Until now, there are more than sixty proofs of the Butterfly Theorem, including the synthetical proof, area proof, trigonometric proof, analytic proof and so on. And based on the extension and evolution of the Butterfly Theorem, people can get various interesting and beautiful results. The definition of the Butterfly Theorem is here below: “Let M be the midpoint of a chord PQ of a circle, through which two other chords AB and CD are drawn; AD cuts PQ at X and BC cuts PQ at Y. Prove that M is also the midpoint of XY.” (Bogomolny) This is the most accurate definition currently. However, Butterfly Theorem has experienced some changes and developments. The first statement of the Butterfly Theorem appeared in the early 17th century. In 1803, a Scottish mathematician, William Wallace, posed the problem of the Butterfly Theorem in the magazine The Gentlemen’s Mathematical Companion. Here is the original problem below: “If from any two points B, E, in the circumference of a circle given in magnitude and position two right lines BCA, EDA, be drawn cutting the circle in C and D, and meeting in A; and...
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...Abstract: In this paper we systematically review and develop nonparametric estimation and testing techniques in the context of econometric models. The results are discussed under the settings of regression model and kernel estimation, although as indicated in the paper these results can go through for other econometric models and for the nearest neighbor estimation. A nontechnical survey of the asymptotic properties of kernel regression estimation is also presented. The technique described in the paper are useful for the empirical analysis of the economic relations whose true functional forms are usually unknown. 1 Introduction Consider an economic model y =R(x)+u where y is a dependent variable, x is a vector o f regressors, u is the disturbance and R(x) = E ( y l x ) . Often, in practice, the estimation o f the derivatives o f R(x)are o f interest. For example, the first derivative indicates the response coefficient (regression coefficient) o f y with respect to x, and the second derivauve indicates the curvature o f R(x). In the parametric econometrics the estimation o f these derivatives and testing 1 Aman Ullah, Department of Economics, University of Western Ontario, London, Ontario, N6A 5C2, Canada. I thank L Ahmad, A. Bera, A. Pagan, C. Robinson, A. Zellner, and the participants of the workshops at the Universities of Chicago, Northern Illinois, Stanford, Riverside and Santa Barbara, for their comments on the subject matter of this paper. The work on this...
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...Management journal homepage: www.elsevier.com/locate/wasman Review Electronic waste management approaches: An overview Peeranart Kiddee a,b, Ravi Naidu a,b,⇑, Ming H. Wong c a Centre for Environmental Risk Assessment and Remediation, University of South Australia, Mawson Lakes Campus, Adelaide, SA 5095, Australia Cooperative Research Centre for Contamination Assessment and Remediation of the Environment, Mawson Lakes Campus, Adelaide, SA 5095, Australia c Croucher Institute for Environmental Sciences, Department of Biology, Hong Kong Baptist University, Kowloon Tong, China b a r t i c l e i n f o Article history: Received 27 July 2012 Accepted 8 January 2013 Available online 10 February 2013 Keywords: Electronic waste Life Cycle Assessment (LCA) Material Flow Analysis (MFA) Multi Criteria Analysis (MCA) Extended Producer Responsibility (EPR) a b s t r a c t Electronic waste (e-waste) is one of the fastest-growing pollution problems worldwide given the presence if a variety of toxic substances which can contaminate the environment and threaten human health, if disposal protocols are not meticulously managed. This paper presents an overview of toxic substances present in e-waste, their potential environmental and human health impacts together with management strategies currently being used in certain countries. Several tools including Life Cycle Assessment (LCA), Material Flow Analysis (MFA), Multi Criteria Analysis (MCA) and Extended Producer...
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...are derived from plants that have been used by traditional medical practitioners (Cragg and Newman, 2005). It is a fact that traditional systems of medicine have become a topic of global importance. African countries are at a stage where traditional medicine is considered more for its capacity to generate other medicine than for its own sake. In many cases research undertakings and the commercial use stemming from that research have always relied on information provided by the local communities and, in many instances, have hardly benefited from the research results (Rukangira, 2004) . In Africa, traditional healers and remedies made from plants play an important role in the health of millions of people. (Rukangira, 2004). Typically, studies on the medicinal plants such as Alstonia boonei have focused on the bioactivity of its chemical constituents, ethnobotany, pharmacology, and taxonomy. However, a comprehensive or systematic review on the plant is lacking. Furthermore, in much of the older literature concerning West Africa, the name Alstonia congensis has been erroneously used for Alstonia boonei. Consequently, this paper examined the effect of aqueous bark extracts of Alstonia boonei on the haematological parameters of male wistar abino rats. 1.2 LITERATURE REVIEW 1.2.1 Classification Alstonia comprises about 40 species and has a pantropical distribution. There are about twelve species of the genus Alstonia. Alstonia boonei De Wild belongs to the family Apocynaceae. The...
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...Latino/Hispanic Americans, Native Americans, Asian Americans, Alaskan Natives and Pacific Islanders as compared with the US population as a whole." --National Center for Cultural Competence Population addressed Population addressed In 1950, U.S.-born whites made up about 90 percent of the U.S. population. By 2000, this number declined to about 75 percent, and by 2050 non-Hispanic whites will be in the numerical minority (U.S. Census Bureau 2001, 2002). This rapid diversification requires healthcare organizations to pay closer attention to cross-cultural issues if they are to meet the healthcare needs of the nation and continue to maintain a high standard of care. Looking at the Country as a whole the current area of discussion for this paper is the area of Western North Carolina and the population of Asheville, which is a melting pot of cultures which the combination they create is unique to no other. According to the 2006 U.S. Census Bureau statistics for Asheville, N.C. the current demographics break down as follows: Asheville [City] Population (current estimate), 70,400. Buncombe County Population (2006), 222,174, county in Western North Carolina Asheville is located. Gender Dispersion was 46.8% Male, 53.2% Female with an average age being 39.2 years of age. Race breaks down as follows: White persons (2000), 78%, Black or African American persons(2000), 17.6%, American Indian (2000), 0.4%, Asian persons (2000), 0.9%, Hispanic or Latino origin (2000), 3.8% ( underestimated...
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...PHOTOCATALYSIS AN OVERVIEW1 Radwan A. Al-Rasheed Saline Water Desalination Research Institute Saline Water Conversion Corporation (SWCC) P.O.Box 8328, Al-Jubail 31951, Saudi Arabia e-mail: rdc@swcc.gov.sa ABSTRACT Photocatalysis process, as an environmental application is a relatively novel subject with tremendous potential in the near future. This paper describes the basics of heterogeneous photocatalysis, mainly on TiO2 and the application of photocatalytic processes to water purification and treatment. The paper also reviews more than 50 references covering the wide scale of heterogeneous water phase applications. Finally, a short review of more interesting practical application of photocatalysis for the removal of natural organic matter from seawater is presented. 1. INTRODUCTION Heterogeneous photocatalysis is a rapidly expanding technology for water and air treatment. It can be defined as the acceleration of photoreaction in the presence of a catalyst. The initial interest in the heterogeneous photocatalysis was started when Fujishima and Honda discovered in 1972 the photochemical splitting of water into hydrogen and oxygen with TiO2 [18]. From this date extensive work has been carried out to produce hydrogen from water by this novel oxidation reduction reaction using a variety of semiconductors. In recent years interest has been focused on the use of semiconductor materials as photocatalysts for the removal of organic and inorganic species from aqueous or gas phase. This...
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...Name of the Assignment: Characterization and Applications of Lipases Course Title: Enzymology Course ID: BTC 517 Date of Submission: 3 August, 2012 Submitted To: Professor Naiyyum Choudhury Coordinator,Biotechnology MNS Department BRAC University Mohakhali, Dhaka Submitted By: Sultana Rownok Jahan M.S Biotechnology Summer 2012 MNS Department BRAC University Mohakhali,Dhaka. Introduction: Lipases are the special kind of esterases belong to subclass 1 of hydrolytic enzyme class 3 and have been assigned sub-sub class 3.1.1 due to their specificity for carboxylic acid ester bonds. Lipases (triacylglycerol acylhydrolases, E.C. 3.1.1.3) are ubiquitous enzymes of considerablephysiological significance and industrial potential. Lipases catalyze the hydrolysis of triacylglycerols to glycerol and free fatty acids. In contrast to esterases, lipases are activated only when adsorbed to an oil–water interface (Martinelle et al., 1995) and do not hydrolyze dissolved substrates in the bulk fluid. A true lipase will split emulsified esters of glycerine and long-chain fatty acids such as triolein and tripalmitin. Lipases are serine hydrolases and contain the consensus sequence G – X1 – S – X2 – G as the catalytic moiety, where G – glycine, S – serine,X1 – histidine and X2 – glutamic or aspartic acid .Lipases display little activity in aqueous solutions containing soluble substrates. In contrast, esterases show normal Michaelis–Menten...
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