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Huang Qi

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Huang Qi
Chinese Medical Herbology has always been the old companion of Traditional Chinese Medicine in the area of treatment. Their companionship has stretched back as far as four thousand years with archaeological evidence. Of the ten thousand herbs being documented, Huang Qi is to be thoroughly discussed in regards to its historical origins, botanical features, herbal properties, its use in Chinese medicinal treatment and contraindications and its modern use. Huang Qi is a fascinating herb that has stood the test of time. Chinese practitioners have never failed to utilise it in their clinics and practices.
Origin and Botanical features
Huang Qi 黃耆, roughly translated as "yellow leader", is also known by the pharmaceutical name Astragalus propinquus, It is one of the 50 predominantly used herbs that make up the fundamentals of Chinese Medicine. In some instances, it can also be known as Bei Qi. It was first recorded in Shen Nong’s Materia Medica about 2000 years ago and was then believed to stimulate immune function, invigorates Qi in the Chinese understanding (Braun, 2008).
It is grown in the provinces of Jiangsu, Hubei, Maoshan, Henan, Inner Mongolia, Hebei, Shanxi, Liaoning and Heilongjiang, and predominantly acquired during spring and autumn where the hairy rootlets are removed and the actual plant itself is dried in the sunlight. Currently, microwave drying technology is employed because of easy extraction of effective components and constituents (Qianqian, Junhong, & Jun, 2011).

Nature of the Herb
There are 4 natures identified in Chinese Herbal Medicine, with neutral not being considered as a nature: cold, cool, warm and hot. Huang Qi is mostly sweet in flavour and warm in property. It is categorised in the Tonic category due to its primary use of tonifying spleen and lungs and works on the spleen and lung meridians. A basic yin yang application can be applied with looking closely at Huang Qi's effects on the spleen and lung Tai Yin meridians. Huang Qi has been recorded to have yang effects in its warming interaction with these meridians.
Huang Qi has the predominate yang effects of being warming with the ability to relieve and eliminate cold patterns or pathogenic invasions of the body. Cold patterns can manifest with chills, cold limbs, nasal discharge, typical cold symptoms, body preference for warmth etc. Also, sinking of middle Qi causing diarrhoea can be resolved by Huang Qi due to its yang uplifting nature to relieve this condition. Additionally, Huang Qi's yang nature is reinforced by it's vasodilating ability, promoting and speeding the process of cell healing and growth. Using yin yang philosophy, it is easy to see how Huang Qi works best with cold related symptoms to restore balance and harmony to the body by using opposite forces. It is also noted that Huang Qi has tonifying actions with deficient syndromes.
Therapeutical actions and clinical use
There is a huge plethora of therapeutic and clinical uses of Huang Qi, in both Western and Traditional Chinese medical practices. They are as listed below:
Traditional Chinese Medicine Practitioners Clinical Uses:
• Acts on Spleen and Lung channels, helping with ascending Qi and warming the channels. Additionally, it is uplifting and ascends Yang Qi.
• Tonifies Lung Qi and stabilises Defensive Qi (Wei Qi) and consolidate the exterior. Weak defensive Qi produces sweating symptoms and susceptibility to flu and colds. A patient precipitating cold exterior patterns will benefit greatly from Huang Qi.
• Tonifies middle jiao, particularly invigorating the spleen. Conditions such as oedema which is a result spleen Qi deficiency requires tonification with Huang Qi. Consequently, improved muscular strength will likely occur, for muscles are governed by the spleen, according to the Zang Fu organ system.
• Dries dampness in spleen and stomach indicated by symptoms of anorexia, nausea, vomiting, greasy tongue coating. Also can be used in conditions of arthritis which has been identified as cold damp obstruction syndrome in Chinese medicine, showing aching, swelling and weakness of loins and knees. Often combined with Qiang Huo, Fang Fend, Xi Xin and Huang Bai.
• Improves eyesight.
• Promote diuresis.
• Promotes the discharge of pus and healing of tissues, useful in treating chronic ulcers with difficulty in healing(Sherman, 2009).
In summary, Huang Qi covers Qi deficient syndromes, pertaining to Spleen and Lungs predominantly. However, it also has additional affects on the Kidneys, Stomach and potentially Heart through Zang Fu organ connection. Thus, it is classified as a Qi Tonic in Chinese Herbal Categorisation.
Western herbalists, scientists and health professionals uses:
1. Viral and bacterial infections- (seen as antibacterial and antiviral) This predominantly includes common colds (Braun, 2008) and Upper Respiratory tract infections.
2. Cardiovascular disease - used as a hypotensive agent
3. Impaired immune functions - It has shown to have regulating and positive effects on the immune system due to its promotion of blood cell production. Can be used as a vasodilator and to speed cell healing processes in the body. It has been shown that these factors help with patients undergoing chemotherapy or radiation therapy (Braun, 2008) with consequential cell degeneration, whether being an acute or chronic disease. Anti-inflammatory use is also noted.
4. Kidney disorders. Has been used for Chronic Nephritis and diabetes. Is seen as a diuretic in kidney use (Chen, Li, & Diebschlag, 2000)
5. Oncology - there is growing use of this herb in breast, cervical and lung cancer with ongoing research and development
Contraindications
There are many varieties of the species astragalus ( Huang Qi ) 黃耆. Some are toxic however (Chen et al., 2000). Varieties used in Chinese herbal medicine is regulated and safe but in rare cases, it may cause rashes, observed in patients with spleen deficiency and serious kidney yang deficiency. Recommended dosage is 10-30g.
Huang qi is indeed a strong tonic and can raise the function of the body, thus it is not suitable to use in acute infections, like colds or flu, boils, skin ulcers, yin deficiency with fever and digestive tract infection (Mole, 2007). However, Western Medicine do see the potential of Huang Qi in treating these conditions therefore it is narrowed to the dosage use and close monitoring when utilising this herb.
Modern Research
Pharmacologically, Huang Qi has show to contain a vast number of chemical constituents. This includes "60 components, including b–sitosterol, glycosides (astragalosides I–VII, soyasaponin, daucosterin), polysaccharides (astroglucans A–C), saponins, plant acids, choline, betaine, matakenin, formonetin (an isoflavone), calyosin, amino acids (including GABA) and various micro-elements" (Braun, 2008). Thus, it is no surprise that the herb in pharmacological testing showed multiple pharmacological effects. "Studies have revealed that astragalus has immunostimulant, diuretic, anti-oxidant and anti-inflammatory activities. It also has effects on cardiac function and may possibly have benefits in cancer." (Braun, 2008)
Various clinical studies indicates indisputable evidence of Huang Qi in the area of cardiovascular disease. Huang Qi's chemical constituents showed to affect cardiac function, particularly arrythmia and creatinine kinase levels, and possible improvement on endothelial function. A Chinese study showed that heart function is improved in Chronic Heart Failure patients with granule administration to patients identified with lung deficiency and/heart yang deficiency (Sherman, 2011).
In oncology, there is slight suggestion that Huang Qi has anti-tumour effects in chemoprevention. Currently, "in-vitro and in-vivo" studies demonstrated successful anti-tumor results on experimental tumours in different organ locations. Chemotherapy presents risks of subsequent tumour growth after a multiple chemotherapy treatment sessions. One randomised study of 120 cancer patients receiving chemotherapy using Huang Qi extract showed slowed tumour growth compared to the control subjects of the study. A korean team has also found that a simple decoction of Huang Qi helps with anorexic cancer patients, improving their appetite and increasing weight gain (Sherman, 2010).

Studies in rat models have produced astounding effects, attracting alot of attention of Huang Qi as a diuretic, anti-oxidant and anti-inflammatory. Results showed that the rats produced decreased glomerular hyperperfusion and improved kidney function(Zhu et al., 2011). These studies and trials are an ongoing process but is stimulating the Western Medical society to accredit Chinese herbal use of Huang Qi.(Sun, Xu, & Xu, 2012) The promising results are the driving force for more experimentation and confirmation in the hopes of making this herb's potential optimally used and produced for those who need it.

Conclusion

Huang Qi is indeed an ancient but critical species in the Chinese Herbal family. The ongoing benefits of this herb in clinical use as well as innovative research in the Astralagus species is evidence to its efficacy. It is indisputable that this herb will be continually used in the future of medicine from the overwhelming scientific and historical evidence in its vast functions. It's use as a Tonic in the Chinese medicine family partnered with overwhelmingly beneficial pharmaceutical uses leaves us in no doubt that Huang Qi will never cease to be used in the area of medicine.

References
Braun, L. (2008). Astragalus: Astragalus membranaceus. Journal of Complementary Medicine: CM, The, 7(3), 44-47.
Chen, S. Y., Li, F., & Diebschlag, F. (2000). A clinical guide to Chinese herbs and formulae. New York: Churchill Livingstone.
Mole, P. (2007). Acupuncture: for body, mind and spirit. Oxford: Spring Hill.
Qianqian, D., Junhong, Y., & Jun, Z. (2011). Effect of drying techniques on extraction of Astragalus pieces. Asia‐Pacific Journal of Chemical Engineering, 6(2), 301-304. doi: 10.1002/apj.433
Sherman, L. (2009). Astragalus enhances wound healing. The Journal of Chinese Medicine(91), 80.
Sherman, L. (2010). Huang Qi improves cancer anorexia. The Journal of Chinese Medicine(93), 80.
Sherman, L. (2011). Astragalus beneficial in heart failure. The Journal of Chinese Medicine, 2011(97), 71.
Sun, T., Xu, H., & Xu, F. (2012). Astragalus injection for hypertensive renal damage: a systematic review. Evidence-based complementary and alternative medicine : eCAM, 2012(Journal Article), 929025. doi: 10.1155/2012/929025
Zhu, C., Huang, S., Ding, G., Yuan, Y., Chen, Q., Pan, X., . . . Zhang, A. (2011). Protective effects of Huang Qi Huai granules on adriamycin nephrosis in rats. Pediatric Nephrology, 26(6), 905-913. doi: 10.1007/s00467-011-1808-y

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