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Infants with Intrauterine Drug Exposure

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Infants with Intrauterine Drug Exposure

Between 400,000 and 440,000. That is the number of estimated infants affected by prenatal alcohol or illicit drug exposure each year according to the National Center on Substance Abuse and Child Welfare. That is between ten and eleven percent of all births and frankly that number is way too high. Major maternal substances of abuse that affect newborns are amphetamines, opiates, cocaine, tobacco and alcohol. These substances can have severe adverse neonatal and long term effects. What is to blame for this extremely elevated statistic? Well, illicit drug use by a mother-to-be or even the use of legal substances such as alcohol or tobacco coincides with several other influences that can also impact a child’s life. Examples include lack of prenatal care, socioeconomic status, role of the father, support systems, and the caregiving ability of the mother, all of which play enormous roles in child development and maternal drug use. Almost all drugs of abuse follow a similar mechanism of action in the adult brain; this mechanism alters the pathways for reward by flooding the circuits with dopamine. Dopamine is a neurotransmitter that exists in areas of the brain that power movement, motivation, emotion, and feelings of pleasure. The overstimulation of this system produces euphoric effects in response to the drugs. This reaction initiates the cycle that tells people to keep abusing drugs. As a person continues to abuse drugs, the brain adapts to the waves of dopamine by making less dopamine or reducing the amount of dopamine receptors in the body. The user then has to use more drugs to achieve a dopamine high or even maintain a normal dopamine level (Koob, 2001). So addiction appears to happen when continued use of a drug changes the way your brain feels pleasure. When people are addicted,

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