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Informative Imaging Essay

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Radioactive elements are unstable and emit radiation in the form of alfa, beta and gamma rays. The radiations can be used in nuclear medicine imaging, treatment, drug testing and sterilization in hospitals. Nuclear medicine imaging provides information about function and structure, using safe, not invasive, and cost-effective techniques for diagnosis and therapy. A number of radioactive substances have been used for the different purposes depending on their suitability.

One of the most informative imaging techniques available in medical diagnostics is positron emission tomography (PET). A positron-emitting radionuclide is introduced, usually by injection, and accumulates in the target tissue. As it decays it emits a positron, which promptly combines with a nearby electron resulting in the simultaneous emission of two identifiable gamma rays in opposite directions. These are detected by a PET camera and give very precise indications of their origin. It is a very powerful and significant tool which provides unique information on a wide variety of diseases from dementia to cardiovascular disease and cancer. Organ malfunction can be indicated if the isotope is either partially taken up in the organ (cold spot), or taken up in excess (hot spot). If a series of images is taken over a period of …show more content…
Nuclear medicine imaging, in particular PET allows the detection and monitoring of a variety of biological and pathophysiological processes. Radiotracers are used to elucidate a drug’s absorption, distribution, metabolism, and excretion. This information can be used for understanding drug dosage and toxicity. In this regard, 64Cu (t1/2 = 12.7 h) has been identified as an emerging PET isotope. Its half-life is sufficiently long for radiolabelling a range of target agents and its ease of production and adaptable chemistry make it an excellent radioisotope for use in molecular

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