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MDMA Synthesis

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Originally in the 1970s, 3,4-methylenedioxymethamphetamine (MDMA) had a distinct purpose, and this purpose was to be used in psychotherapy. MDMA, however, had not been approved by the FDA nor had the drug undergone clinical trials. The DEA placed a ban on MDMA in 1985, since the ban MDMA has not been used for legal psychotherapeutic treatments. Until recently, MDMA was believed to have no clinical value, and was not used for more than a party drug. New research has also been conducted to determine how MDMA affects the brain, and the FDA has approved phase three clinical trials. Studies have shown that MDMA cures people who have been suffering with PTSD.

MDMA originally dates back to the beginning of the 1900s in the country of Germany. …show more content…
The amygdala, which is the part of the brain associated with fear, has shown decreased activity (Miller, 2016). The brain has also been observed to increase certain hormones such as oxytocin and prolactin. The decreased activity of the amygdala; and the increase of serotonin, oxytocin, and prolactin puts the user in the “optimal arousal zone”. Moreover, this zone is between hyperarousal and hypo-arousal where the patient can have several hours where therapeutic change can occur. Additionally, MDMA has also shown the increase the activity of the prefrontal cortex, which is associated with information processing. A study conducted by Dr. Michael Mithoefer, compares before and after brain scans of patients with PTSD. Although the results are still being processed the study shows that the effects of MDMA are opposite to those of PTSD (Miller, 2016). The results are showing that MDMA can cure people who are suffering with …show more content…
The approval was based on the findings of the phase two clinical studies (Kupferschmidt, 2017). The results are unpublished, however the results of the phase two studies have been reviewed by the FDA. Furthermore, in phase two studies, 107 participants suffered from PTSD, 68% of those patients no longer had PTSD after one year (Burns, 2017). Phase three trials are set to start in early 2018 and will include approximately 200- 300 hundred PTSD suffering patients, if the Multidisciplinary Association for Psychedelic Studies (MAPS) can come up with the funding. Out of 107 patients 68% were cured of PTSD effects, and those that were suffering used MDMA to help cure their

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