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Major Depressive Disorder: A Case Study

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Major Depressive Disorder (MDD) is one of the most common and serious mental disorders (Kessler et al., 2005) and can cause great dysfunctionality in the daily lives of its sufferers, including co-morbidity and suicidality. It is important to establish the best treatment offers for depressed individuals in order to give them the best chance at recovery. Many studies have looked at the effects of psychotherapy, pharmacotherapy, and combination therapy to determine which is best for treating depression. Presented in this paper are two studies who researched the differences. Results were similar to previous studies in that each treatment is equally effective at improving depression in individuals (Iftene, Predescu, Stefan, & David, 2015; …show more content…
Blais and his colleagues and their study (Study 2) titled, “Treatment as Usual (TAU) for Depression: A Comparison of Psychotherapy, Pharmacotherapy, and Combined Treatment at a Large Academic Medical Center” (2013) recruited participants through an urban hospital by having each patient beginning outpatient care complete an initial outcomes form and follow-up ratings every 13 weeks that collected data regarding demographics, treatment types, diagnoses following DSM-IV, Global Assessment of Functioning ratings, and brief measures of psychological health and distress. The initial outcomes form indicated to which treatment group each participant would be assigned. In the end, 115 patients were assigned to the psychotherapy group, 486 to the pharmacotherapy group, and 785 to the combined treatment …show more content…
Although there seemed to be a small effect towards the REBT/CBT group (67.85%) versus pharmacotherapy (60.60%) versus combination (52.84%), this effect was too insignificant to hold any clinical value (Iftene, Predescu, Stefan, & David, 2015). The table below illustrates the results. Table 1: This shows the results of Study 1. There is an insignificant effect size towards the REBT/CBT treatment. Study 2 found that when treating an individual with MDD, any treatment is better than none. They found no significant differences between each condition (with an overall effect size of 0.61) (Blais, et al., 2013). The table below gives the percentages of individuals who worsened and improved their depression. As depicted, the number of patients who had improved symptoms of depression varies very little in relation to each separate treatment. Table 2: Table credited to Mark A. Blais and colleagues (2013).

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