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Micro Project 1 Outline

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Module 4 Project 1- Out line
Amy Vinson

Lyme Disease:
Historic time line:
1909- Swedish physician Arvid Afxelus observes a bull's eye rash around a patient's tick bite.

1930-1940- Swedish dermatologist Sven Hellerstrom links erythema migrans to meningitis in multiple patients.

1970- First U.S. Case of erythema migrans reported in Milwaukee, Wis.

1975- Reseachers link juvenile arthritis cases in Lyme, Conn. To tick bites.

1977- Yale rheumatologist Allen Steere provides the first definitive account of the disease

1980- The CDC begins to monitor the spread of Lyme Disease

1982- Zoologist and microbiologist Willy Burgdorfer of the National Institute of Allergy and Infectious Diseases Rock Mountain Lab, Mont., isolates the bacterium that causes Lyme Disease, Borrelia burgdorferi. The CDC reports 492 cases of Lyme Disease.

1984- Westchester County, NY declares a Lyme epidemic

1988- CDC reports 4,572 Lyme cases

1991- CDC requires state and local health departments nation wide to collect and verify data on Lyme infections

1994- CDC adopts two-step test standard to diagnose Lyme Disease.

1998- CDC records 16,802 cases of Lyme. Drugmaker SmithKline Beecham begins marketing Lymerix vaccine.

2002- The maker of Lymerix withdrawals the vaccine from the market after controversy over alleged side effects undercuts demand.

2006- Infectious Diseases Society of America publishes Lyme guidelines that find no convincing scientific evidence for the existence of chronic Lyme Disease. Connecticut attorney general Richard Blumenthal opens an antitrust investigation of IDSA's disease guideline panel.

2007- Lyme Disease Association and Lyme Research Alliance establish Lyme and Tick-Borne Diseases Research Center of Columbia University to focus attention on patients with chronic persistent Lyme symptoms.

2008- IDSA commissions an independent panel to review its guidelines

2010- Review panel concludes that IDSA guidelines are scientifically valid but identifies area for future review.
2011- Drug maker Baxter International launches phase 1 and 2 trials of a new Lyme Disease vaccine in Europe. CDC researches trace 159 cases of the tick-borne disease babesiosis came from blood transfusions between 1979 and 2009, raising concerns about tick-borne infections moving into the U.S. Blood supply.

2012- National Institutes of Health-funded study finds Lyme bacteria remaining in monkeys treated for 4 wees with antibiotics. CDC study finds that a tick pesticide reduces the number of ticks but not the number of tick-borne illnesses.

2013- Baxter announces success in phase 1 and 2 Lyme vaccine trials. CDC estimates from preliminary data that 300,000 Americans are infected with Lyme Disease annually, compared to about 30,000 reported cases.

Summary of Current Understanding:
Today, we are researching whether Lyme Disease can have chronic side effects. We know the disease comes from a bite from an infected tick. Many people have heard of Lyme Disease but do not know the seriousness of the disease. We do know that current symptoms are treated with antibiotics, but levels of the bacteria remain after treatment.
A projection of where the next major advance of breakthrough in our topic will come from:
Baxter has been on the path to a vaccine to prevent Lyme Disease. The next advance in Lyme Disease treatment and prevention lies with the successful release of that vaccine. Maybe if we are vaccinated, but do still get the disease, the antibiotics will no longer leave traces of disease in the system. The next advancement that needs to be made is a cure for those already infected if we can find and produce a successful vaccine to prevent the disease, a cure will be right around the corner. I believe that eventually, a vaccine for Lyme Disease prevention will be part of the routine vaccines we are given throughout childhood and into adulthood.

Citation

Weeks, J. (2013, November 8). Lyme Disease. . Retrieved July 24, 2014, from http://library.cqpress.com.vlib.excelsior.edu/cqresearcher/document.php?id=cqresrre2013110800&type=hitlistνm=2

Lyme Disease. (2014, May 7). . Retrieved July 24, 2014, from http://www.cdc.gov/lyme/

Diseases and Conditions: Lyme Disease. (2012, October 3). . Retrieved July 24, 2014, from http://www.mayoclinic.org/diseases-conditions/lyme-disease/basics/definition/con-20019701

Prevention Products. (2013, April 2). . Retrieved July 24, 2014, from http://www.aldf.com/fourPoster.shtml

Lyme Disease. (2014, March 1). . Retrieved July 24, 2014, from http://familydoctor.org/familydoctor/en/diseases-conditions/lyme-disease.printerview.all.html

Lyme Disease Introduction. (n.d.). . Retrieved July 24, 2014, from http://www.lymedisease.org/lyme101/lyme_disease/lyme_disease.html

Joseph, MD, E. B. (2013, July 31). Infections: Lyme Disease. . Retrieved July 24, 2014, from http://kidshealth.org/parent/infections/skin/lyme.html#

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