...established ethical principles to protect human participants in biomedical research from undue exploitation by researchers. However, in the “Tuskegee Study” in the US, these principles were grossly violated. The task of this paper is to critically examine the ethical implications of that study on future practices in biomedical research, and to suggest ways of ensuring that such practices comply with appropriate ethical values. Key Words Bioethics, Biomedical research, clinical research, Tuskegee Study, paternalism, morality Introduction From time to time human beings experience health challenges, whether physical or mental. On its part, medical practice has made considerable progress towards combating or controlling many of these challenges. It is through research that the nature, symptoms and effects of ailments can be ascertained and remedies discovered. Medical researchers engage in both therapeutic and non-therapeutic research. Therapeutic research is that carried out with the purpose of treating disease. On the other hand, non-therapeutic research is aimed at 76 Adebayo A. Ogungbure furthering the frontiers of knowledge about human health. Furthermore, researchers and physicians often use human beings as objects of scientific investigation, raising certain ethical concerns, including the issue of informed consent and how consent is obtained, selection of participants in research, the welfare of human...
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...are established ethical principles to protect human participants in biomedical research from undue exploitation by researchers. However, in the “Tuskegee Study” in the US, these principles were grossly violated. The task of this paper is to critically examine the ethical implications of that study on future practices in biomedical research, and to suggest ways of ensuring that such practices comply with appropriate ethical values. Key Words Bioethics, Biomedical research, clinical research, Tuskegee Study, paternalism, morality Introduction From time to time human beings experience health challenges, whether physical or mental. On its part, medical practice has made considerable progress towards combating or controlling many of these challenges. It is through research that the nature, symptoms and effects of ailments can be ascertained and remedies discovered. Medical researchers engage in both therapeutic and non-therapeutic research. Therapeutic research is that carried out with the purpose of treating disease. On the other hand, non-therapeutic research is aimed at 76 Adebayo A. Ogungbure furthering the frontiers of knowledge about human health. Furthermore, researchers and physicians often use human beings as objects of scientific investigation, raising certain ethical concerns, including the issue of informed consent and how consent is obtained, selection of participants in research, the welfare of human subjects involved in...
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...through research that the nature, symptoms and effects of ailments can be ascertained and remedies discovered. Medical researchers engage in both therapeutic and non-therapeutic research. Therapeutic research is that carried out with the purpose of treating disease. On the other hand, non-therapeutic research is aimed at 76 Adebayo A. Ogungbure furthering the frontiers of knowledge about human health. Furthermore, researchers and physicians often use human beings as objects of scientific investigation, raising certain ethical concerns, including the issue of informed consent and how consent is obtained, selection of participants in research, the welfare of human subjects involved in a research project, what the goals of research ought to be, and what ought to constitute proper procedure for an ethical research. These issues are central to an aspect of applied ethics which is now commonly referred to as research ethics. The aim of research ethics is to ensure that research projects involving human subjects are carried out without causing harm to the subjects involved. In addition, it provides a sort of regulatory framework which ensures that human participants in research are not exploited either physically or psychologically. The need for ethical guidelines for biomedical research is expressed in some of the questions research ethicists are concerned about, including the following: • What are appropriate clinical endpoints that should trigger the termination of a trial? • Are...
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...Ethical Principles Paper Kalina Anderson University of Phoenix May 18, 2015 Introduction Ethics is defined as the branch of philosophy that involves systematizing, defending, and recommending concepts of right and wrong conduct. More simply put, it is the standards that members of a profession must follow. In psychology, ethics plays a big role in psychology because it protects the client and the counselor as well. However, in the case on Henrietta Lacks, it seems that there was no room for ethics during these scientists studies. Henrietta Lacks was a poor black tobacco farmer whose cells were taken without her knowledge in 1951. She was considered one of the most important tools in medicine and vital for developing the polio vaccine, cloning gene mapping, and more (Skloot, 2010). Summary In an Internet video, Film Media Group (2012) states that in 1860, Benjamin Lacks had two children by a black mistress and they all worked in the tobacco field for three generations. Then, in 1942, Benjamin Lack's great granddaughter Henrietta Lacks (her friends called her “Hennie”) moved to Baltimore and died there in 1951. Right before she died, her cancer cells were taken from her body to help research and “conquer death.” Since then, her cells have been growing and multiplying since. There was a laboratory close to where Henrietta lived. In that laboratory was Dr. George Gey who wanted to rid the world of cancer. After a gynecologist appointment, abnormal...
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...The Holocaust: Suggested Reading There is a wealth of information about the Holocaust. So much has been written, in fact, that it can be difficult to determine where to start. This reading list is collected from recommendations from other members of The Holocaust History Project. It is not a complete bibliography but represents our opinion as to what are the most useful starting places for research. Since this list concentrates on works that are easily available and useful to a person unacquainted with the history of the Holocaust, many excellent books which are rare or out of print are not listed. Another class of books that are not included is works that are controversial because of their contents or the unusual theories they propose. Some of these are excellent works, others are not. But we feel that the reader for whom this list was compiled would not have the knowledge needed to evaluate these discussions of the legitimate controversies about the Holocaust. Just as a medical student must learn anatomy before he or she is taught surgery, someone studying the Holocaust must know the factual background before some of the more technical studies can be understood. As well as general works we have included books of specialized interest concerning the matters about which we at The Holocaust History Project are most frequently asked. Many of these books deal with more than one subject, but in the interest of brevity we have not cited a book more than once. General history of the...
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...significant bearing on his career in the SS. Eichmann was adept at learning practical skills on the job, under the tutelage of seniors he respected. While he continued to live at home, he ranged over Upper Austria selling oil products, locating sites for petrol stations, and setting them up. He also arranged kerosene deliveries. On Saturday he conscientiously completed his paperwork and reported to his superiors. Eichmann did well and was transferred to the Salzburg district. But by 1933 he had tired of the job and, anyway, was laid off. He had learned a lot, though: how to identify prime sites at communication junctions, how to timetable and organise deliveries, how to sell a product and persuade people to do your bidding. During his trial he pretended to be apolitical, but Eichmann came from a strongly German nationalist family. Like many Germans his father lost his wealth during the post-war economic crisis and had the embittering experience of starting all over again. He enrolled his son in the Wandervogel youth movement which, while ostensibly apolitical, was strongly imbued with völkisch ideas about the Heimat (homeland). Later, Eichmann joined the Linz branch of the Heimschutz, a right wing paramilitary association of army veterans. In April 1932, he joined the Nazi party. At the instigation of the local gauleiter, who knew his family, he attended a Nazi rally and was approached...
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...Sara Wadlow PS 434 Research Paper May 3, 2015 Introduction The Syrian Civil War has resulted in the deaths of hundreds of thousands of people. Since 2011, protests and attacks have been a daily occurrence, and the regime of Bashar Al-Assad has done what it believed was necessary to stop rebel forces and end protests. As such, Assad has committed many questionable, at best, and criminal, at worst, actions against the civilians of Syria in an effort to stop the rebels. The indiscriminate warfare Assad has used against Syrian citizens is shown in multiple international doctrines as illegal, and is thus a war crime, which should be prosecuted. The Statue of the International Criminal Court defines war crimes as “serious violations of the laws and customs applicable in international armed conflict” and “serious violations of the laws and customs applicable in an armed conflict not of an international character (ICRC 2016). Section IV of Rule 156 of the International Committee of the Red Cross, titled Other Serious Violations of International Humanitarian Law Committed During a Non-International Armed Conflict, lists use of prohibited weapons subject to criminal sanctions, and specifically references the Chemical Weapons Convention, Amended Protocol II to the Convention on Certain Conventional Weapons, and the Ottawa Convention as laying the groundwork for this guideline. This paper will address historical context of the Syrian Civil War, United Nations documents concerning...
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...Prisoner research is a debatable topic on ethics and morals. It can be viewed as a negative practice mostly because of its history. During World War II, prisoners were forced into concentration camps by the Nazis to be tested on. The testing done at these concentration camps were a horrific scene to any of who liberated them. The Nazis weren't the only ones who tested on prisoners, but also it caused controversy in the U.S. These are considered among the most egregious cases of widespread abuse of human subjects of research in modern history (Stone pg. 6). Because of this prisoner research is viewed just like it was 70 years ago, except it hasn't changed too much since. Prisoner research is thought to be humane today, but that's just what the public know. Prisoners should not take part in medical research because they are a vulnerable population; they may feel coerced to...
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...Scholarly Commons 2007 Biomedical Research Involving Prisoners: Ethical Values and Legal Regulation Lawrence O. Gostin Georgetown University Law Center, gostin@law.georgetown.edu Georgetown Public Law and Legal Theory Research Paper No. 976413 This paper can be downloaded free of charge from: http://scholarship.law.georgetown.edu/facpub/479 http://ssrn.com/abstract=976413 297 JAMA 737-740 (2007) This open-access article is brought to you by the Georgetown Law Library. Posted with permission of the author. COMMENTARIES Biomedical Research Involving Prisoners Ethical Values and Legal Regulation Lawrence O. Gostin, JD U NTIL THE EARLY 1970 S , R. J. R EYNOLDS , D OW Chemical, the US Army, major pharmaceutical companies, and other sponsors conducted a wide variety of research on prisoners—a captive, vulnerable, and easily accessible population.1,2 During that time, approximately 90% of all pharmaceutical research was conducted on prisoners, who also were subjected to biochemical research ranging from testing diet drinks and simple detergents to studies involving dioxin and chemical warfare agents.3 From 1962 to 1966, for example, 33 pharmaceutical companies tested 153 experimental drugs at Holmesburg Prison in Philadelphia, including a Retin-A (tretinoin) study in which researchers did not seek informed consent and prisoners were not adequately treated for pain.4 By the mid-1970s, biomedical research in prisons sharply declined as knowledge...
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...hear about so many terrible incidents catalyzed by one patient’s cells. The historic lens shows us that “historically, the health care institution has failed, humiliated and ruined lives in the effort to improve medicine” (Robbennolt, 2009) , and it is important for us as social workers to look through that gloomy, grim lens and envision interventions that would have prevented it from becoming so. In a twisted irony of life, one woman’s ill fate, gave way to many discoveries that have saved many lives, but unfortunately at a heavy price for others. One such story involves a virologist named Charles Southam. The man I call the “The cancer needle gambler” * How horrified would you be with the following scenario? A physician is conducting research on human immunodeficiency virus in 1982 is experimenting the possibility that it can be spread through saliva by having terminally ill patients ingest large quantities of saliva mixed with...
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...Recruitment and Retention of Minority People in Clinical Trials Name Course Tutor Date Introduction Clinical trials are faced by numerous problems among them being difficulties in recruitment and retention of minority groups. The challenges that are faced in recruiting and retaining these groups have been well documented through various researches. In order to successfully recruit and retain minority people in clinical trials research in the health fields must undertaken beyond the traditional methods so that the barriers prevalent in the process of recruitment and retention can be overcome. Some of these barriers are related to mistrust and fear of science-based experiments following a history of atrocities committed in the name of science (Area, Alvidrez, Nery, Estes, & Linkins, 2003). This essay is going to highlight the strategies to increase recruitment and retention of minority people participation in clinical trials. Discussion Background Ethical consideration in medical research and clinical trials particularly with regard to humans came into the limelight in the first half of the 20th century following the medical experiments conducted by the Nazis on humans. These experiments saw the development of the Nuremberg code, which began a wide range of regulations that emphasized on the need for the protection of human beings who participated in trials that were prevalent in medical research. Principles that were articulated under the code...
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...Administrative Ethics: Advances in Lung Cancer Care HCS/335 Tuesday, March 20th, 2012 Administrative Ethics: Advances in Lung Cancer Care In this paper, there will be a description of what the newspaper article covers about Lung Cancer treatment plus the population this issue affects the most. Examples the article uses to argue or present facts supporting the treatment research of Lung Cancer Patients, explanation of ethical and legal issues do to the involvement this article is talking about, explanation of the managerial responsibilities related to administrative ethic issues, and identification of proposals to create solutions. Description of Newspaper Article and Those It Affects “More Americans die from lung cancer each year than from breast, colon and prostate cancers combined, according to the National Institutes of Health. But it has long suffered from a stigma because of its association with smoking, receiving far less research funding than other forms of cancer.” (Thoms, 2012, para. 5-6) In reading the above quote it should inspire some to promote more research completion in the area of Lung Cancer. Factual information such as this is what makes the medical professionals working in the area of Lung Cancer Treatment want to bring this awareness to the general public. Each day these professionals go to their careers and have to witness his or her patients suffering from this horrible disease. Their hands are tied on providing more...
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...Research with human subjects has a long and often troubled history in the United States (U.S.) and throughout the world. Chances are you already have heard of some of the most egregious and well-known examples of unethical research in the biomedical sciences, such as the experiments conducted by Nazi doctors and scientists on concentration camp prisoners during World War II, and the U.S. Public Health Service (PHS) study titled "Tuskegee Study of Untreated Syphilis in the Negro Male" (Tuskegee Study). These abuses led to the creation of codes of research ethics in Europe and the U.S. In the wake of the Second World War, the subsequent Nuremberg Trials on war crimes produced the Nuremberg Code, which outlined ten points for conducting ethical research with human subjects. Nearly two decades later, the World Medical Association (WMA) developed a code of research ethics known as the Declaration of Helsinki, published in 1964 and subsequently revised. This document is built on both the Nuremberg Code and the physician's code of ethics known as the Declaration of Geneva. In the U.S., news that researchers deceived and withheld treatment from subjects who suffered from syphilis in the Tuskegee Study led to the creation of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (National Commission or "the Commission"). The Commission was charged with establishing a code of research ethics for U.S. research involving human subjects. In 1979...
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...AFRICA NAZARENE UNIVERSITY UNIT TITLE : BUSINESS RESEARCH METHODS UNIT CODE : BCM 308 TASK : GROUP WORK STUDENT NO. NAME : NEWTON WANYAMA 12M03EBA074 : LEWIS MUNDIA 12J03ABA007 : JAMES IKUA 12S03EBA003 : MARY ODERO 12S03ABA011 : GLADYS MUMO 12J03EBA011 : PENINAH MBUTHIA : GEORGE OLIWA QUESTION : Discuss the ethical issues in research? DUE: 8 JULY 2013 LECTURER: HANIEL NJOGU MUCHIRI INTRODUCTION When most people think of ethics (or morals), they think of rules for distinguishing between right and wrong, such as the Golden Rule ("Do unto others as you would have them do unto you’’. This is the most common way of defining "ethics": norms for conduct that distinguish between acceptable and unacceptable behavior. Most people learn ethical norms at home, at school, in church, or in other social settings. Although most people acquire their sense of right and wrong during childhood, moral development occurs throughout life and human beings pass through different stages of growth as they mature. Ethical norms are so ubiquitous that one might be tempted to regard them as simple commonsense. On the other hand, if morality were nothing more than commonsense, then why are there so many ethical disputes and...
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...Code of Research Conduct and Research Ethics Code of Research Conduct and Research Ethics Foreword by Pro-Vice Chancellor Research The University of Nottingham‟s Code of Research Conduct and Research Ethics provides a comprehensive framework for good research conduct and the governance of all research carried out across the University. The Code underpins the University‟s commitment to maintaining the highest standards of integrity, rigour and excellence in all aspects of our research and for all research to be conducted according to the appropriate ethical, legal and professional frameworks and standards. The Code is a fundamental component of the research environment which is characterised by our culture of research integrity, good research practice, and the development and training of researchers at all stages of their careers. The Code outlines the duty of researchers including their responsibilities towards all participants and subjects of research including humans, animals, the environment and cultural materials, and it provides a basis for the transparent and appropriate communication and dissemination of research findings. The University welcomes the national framework for good research conduct and governance published as the Concordat to Support Research Integrity and endorses the Concordat as a recipient of public funding for research. This Code has been reviewed to be consistent with the commitments and aims of the Concordat and is the basis for applying...
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