...Personalized Medicine Na’Tasha Slade SCI 115 Professor Palaniswamy August 5, 2012 Personalized Medicine has great influence on the way we think towards identifying and managing healthcare problems and diseases. Personalize medicine aids in providing an in depth analysis of hereditary differences within genetically difference of people and also how it may affect the healthcare that they may need. With technology being modified daily the advancements in technology may improve the levels of personalize medicine by, giving details on someone metabolic, genetic, and proteinaceous profile that in the future be used to customize individual medical care. The concept of personalized medicine has broadened to include evaluation of your genetic risk of developing disease and determining how serious it may be as well as detecting diseases at much earlier stages—usually before you have symptoms. A personalized medicine approach will also tell you what medicines will work best for you, depending on many different factors, and reduce or eliminate the trial-and-error process of trying to find the right ones. A personalized medicine approach will better monitor disease and treatments and have a better chance of predicting outcomes of therapies and treatment approaches. Personalized medicine usually involves a combination of genetic testing (to determine propensity for certain diseases); suggestions for lifestyle changes; detection of diseases at the molecular level; and customized...
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...Wuanda S Green Introduction to Biology Dr. Russell Barnett Personalized Medicine Personalized medicine is a new field of healthcare that is based on an individual’s unique genetic, genomic, clinical and environmental information. The factors vary from one person to another just like the onset of diseases so the purpose of personalized medicine is to react to the individual’s symptoms in the way, with personalized treatment (Jain, 2007). Personalized medicine primary goal and target is to make a treatment as individualize as the person receiving the treatment. This method involves identifying genetic, genomic, and clinical information that will allow accurate predictions to be made about an individual’s susceptibility to a developing disease, the course of that disease and the response to treatment (Cohen, 2008). Modern genetic technology started with the genome project which leads to the benefits and development of personalized medicine (Cohen, 2008). The human genome is the blueprint for each person's body, influencing how we look, our genetic predispositions for certain medical conditions, how well our bodies fight disease or metabolize food, and which therapies our bodies do and do not respond to (Hart, 2005). The genome consists of an organism's total DNA, including its genes. DNA—the famous "double helix"—is composed of four chemicals, which are repeated many times in different sequences (Jain, 2007). (The names of the chemicals are abbreviated as A, T, C, and G. That's...
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...PERSONALIZED MEDICINE Introduction to Biology Professor Thomas Green LaKeyla Garrett Explanation of how modern genetic technology may lead to personalized medicine. By using DNA technologies such as stem cell research and cloning manipulate human genes. Patients with common disease genetic abnormalities and even spinal injuries may use genetic technology to create personal medicine that may be able to improve and prolong life. An individual risk for common disease would be determined by a genetic profile created from this technology. To create a medical profile tailored to specific DNA characteristics of each patient doctors may use modern genetic technology. The genetic profile would determine treatment and/or preventative care according the effects of a particular disease or patient’s reaction to a certain medical treatments. Discuss the benefits of personalized medicine. Prevention, diagnosis, and treatment in some cancers can be provided by personalized medicine. The use of personalized medicine will allow doctors to develop a more precise treatment based on each patients modern genetic technology because cancer is such a complex disease and effects each individual differently. Genetic diseases affect an estimated 12 million Americans, yet according to a survey of 1,000 people conducted by the Genetic Disease Foundation (GDF), while two-thirds of those surveyed were willing to and saw the benefits of undergoing genetic testing, close to 80 percent had never...
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...Personalized medicine is a medical model that emphasizes and bases its application on understanding and using an individual’s personal information. This information includes details about genes, proteins, environmental surroundings during diagnosis, prevention, and in choosing and administering treatments. “Today, when people refer to “Personalized Medicine,” it is generally in the context of using genomics, the science of looking at all the information in the human genome, to tailor medical care to individuals based on their genetic makeup” (Chisholm, 2008). Three areas of technology are the key to making personalized medicine present in our healthcare system. One area involves new tools to decode the human genome (Personalized Medicine: A Vision for a Positive Effect on Healthcare). By mapping this, new approaches have been taken to understand and treat disease. “Cancer and cardiovascular disease are two areas in which genomics are showing promise for treatment advances, although challenges remain” (Personalized Medicine: How Will It Affect Patients?, 2011). The second key area would be to use large-scale studies that help link genetic variation to disease. We would also need “a healthcare technology information system that supports integration of clinical data” (Personalized Medicine: A Vision for a Positive Effect on Healthcare). This would enable physicians to keep track of patient care, to tailor treatment. Breast cancer has been a medical concern for years, and we...
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...Personalized Medicine SCI 115 Abstract Personalized medicine is a healthcare field that deals with the different and unique genomic, genetic, clinical, and environmental information of each person. Personalized medicine is based on making treatment or prevention of disease focus on the individual and the factors that do or will affect that particular individual. Some of the advantages of personalized medicine are the ability to make more informed medical decisions, earlier disease intervention, and reduced probability of negative side effects. Although there is a large upside to personalized medicine and the medical advantages that come along with it implementation, there lyes the challenge. The implementation of personalized medicine is the largest limitation. Whether it is lack of push from the healthcare industry or lack of proven technology to properly diagnose individual patients, personalized medicine is very young and has a long way to go. Personalized medicine or medical treatment that is unique to the individual definitely has it advantages. Some of those advantages are the ability to make more informed medical decisions, earlier disease intervention. Laberge and Burke (2008) describe personalized medicine as health care that is tailored to the individual. They go on to say that (Laberge and Burke 2008) recently the term has been used to refer specifically to genetically-based health care. Some of the drawbacks to personalized medicine according to Laberge...
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...Personalized Medicine Kenneth Weddle Strayer University Science 115 Professor Meri Stanec May 21, 2012 Personalized Medicine Personalized medicine refers to the medical model that entails the customization of healthcare. Under personalized medicine, all the decisions and practices relating to an individual patient are advanced using genetic or any other vital pieces of information. The emergence of personalized medicine has helped in the reduction of costs, time, and the rate of failure of pharmaceutical clinical trials, has eliminated trial and error inefficiencies in the diagnosis of diseases, and has aided in the prescription of effective drugs and averted those that pose dangerous side effects to patients. This essay explicates the manner in which genetic technology may contribute to personalized medicine, examples of the benefits of personalized medicine, and drawbacks of personalized medicine. Modern genetic technology has played an instrumental role in leading to personalized medicine. It has led to in depth understanding of the impacts of genetics in a given disease. The understanding of the impacts of the disease has helped in the development of personalized medicine, as practitioners are able to identify the correct prescription for different diseases. Modern genetic technology has also led to personalized medicine by helping practitioners understand the significance of genes in the normal development...
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...Personalized Medicine Introduction to Biology This paper focuses on the representation of the personalized medicine and how the modern techno-scientific has lead for its evolution. Personalized medicine refers to contemporary techno-scientific advantages in modern medicine, such as vitro fertilization technologies, organ transplantation, stem cell therapy, complex life support technologies, etc. The point here is that these and related developments not only continue to stretch and design life, and to boost life expectancy statistics, especially in advanced countries, but they also pose ethical challenges, disadvantages and support a dichotomous relationship between longevity and quality of life. For example, with hundreds of thousands of test tube babies living in the world, in vitro fertilization (IVF) has become much more common. IVF is usually reserved for instances in which a woman suffers from blocked or damaged fallopian tubes or a man has low sperm count. The typical IVF cycle begins with drug treatment designed to control ovulation. One common method is to take five days of nasally administered gonadotropin-releasing hormone analogue (GnRH) to shut down the ovaries, followed by then days of injections of follicle-stimulation hormone (FSH) designed to spur the production of multiple eggs. Blood tests and ultrasound exams help determine the best time to remove the eggs from follicles in the ovaries, which is done surgically bout 36 hours after an injection of...
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...have been breakthrough and impressive. The benefits of personalize medicine are easily recognized. The major benefits of personalized medicine are early diagnostics and, medication and treatments are personalized to an individual for maximum results. Diagnostics use molecules to measure the levels of genes, mutation, and proteins that can be used in the provision of specified therapy that fits the patient health condition. (Science daily, 2010). Our DNA and genes can determine the likelihood of an individual developing certain diseases and how an individual can react to certain medication and treatments. With personalized medicine, medical professionals can analyze a patients genome and identify risk factors to intervene and begin a treatment plan that will best cure/treat/delay the disease of that particular patient. Personalized medicine can change the way professionals approach diseases and illnesses. It has the ability to alter healthcare to further fit their individual needs. Using the individuals genome, personalized medicine has become a future possibility. Personalized medicine is developing medicine, specifically for the individuals genetic makeup and therefore, the effectiveness of treatments for diseases is more effective for each specific patient. Medicine and treatments can be customized to an individual's medical care, to better treat that individual's specific needs. Personalized medicine will be...
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...How Modern Genetic Technology May Lead to Personalized Medicine While the practice has actually been around for a while now, modern genetic technology is already trying to make its way into mainstream healthcare. There are specialized treatments being developed for breast cancer called Stratified medicine that takes patients and splits them into four groups to see which one respond to the medicine and the ones that don’t are no longer given the treatment. Another treatment is Gene therapy, this treatment looks to change the genome to stop diseases at its root, this treatment has been changed to longer include aggressive courses of action it is now less aggressive and being used more. There are also vaccines available for certain types of cancer as well as ways to reconstruct tissue. Benefits of Personalized Medicine The rise in the technology available to us for our healthcare needs make sure that more and more diseases are stopped before they even get a chance to take hold. Society as whole are becoming more health convince than ever and it is only natural that we would be looking to personalized medicine as our future. Personalized medicine can let us know how well patients will respond to traditional therapies, and allows their health care to be tailored to meet their needs. Patients will then be able to know out front which conditions they would be at greatest risk of contracting and be able to come up with a course of action. Things like change in diets and genetically...
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...The Concept of Personalized Medicine Yvette Stubberfield Strayer University SCI 115 November 16, 2010 Professor Genevieve P. Freeman Personalized Medicine is a new revolutionary break through for doctors and scientists, seeking to treat patients as individuals, based on the actual biology of the disease and not as a member of a population to their symptoms. The whole concept of this new modernized medicine is to avoid wasting time with traditional medicine and risk patients dying before they got the right medicine. The Concept of Personalized Medicine Personalized Medicine is a new revolutionary break through for doctors and scientists, seeking to treat patients as individuals, based on the actual biology of the disease and not as a member of a population to their symptoms. The whole concept of this new modernized medicine is to avoid wasting time with traditional medicine and risk patients dying before they got the right medicine. Scientists have been working on Pharmacogenetics project which is a study of how an individual inheritance variation in genes affect to the body response to a particular drug. Every human being is different and has a unique sequence of genetic information. Individuals respond to drugs differently based on their genes, proteins and environment factors such as: smoking, occupational exposures, alcohol and drug use, exercise and diseases. This study will help tailor drugs to fit our genes...
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...Personalized medicine Personalized medicine is defined as a medical model of customized healthcare in which the medical decisions, practices, and/or products are tailored for the individual patient. In this model, the diagnostic test is often used to select appropriate and optimal treatments based on the context of a patient’s genetic content, other molecular or cellular analysis. The application of genetic information has played an important role in certain aspects of personalized medicine such as pharmacogenomics, and the term was first invented in the genetic background although it has been broadened to encompass a variety of personalization measures [1]. Some use cases of personalized therapies, devices, or technologies that demonstrate...
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...Personalized Medicine And Genetic Technology Introduction to Biology SCI 115 Merec Stances Personalized Medicine and Genetic Technology Genomic Technology or what is more popularly known as Personalize Medicine is the personalization of healthcare, with decisions and practices that are tailored to an individual patient. This involves the process of the use of genetic technology or other gathering of information of an individual patient’s preventative and therapeutic care. After more than a decade the U.S. Department of Energy and the National Institutes of Health received a decade of research which was gathered from the Genome Project, (2003). Under this project the Scientist were to learn the order of 3 billion units of DNA which goes into the making of human genome and also to identify the genes located in all this data. By 2003 there was enough chemical makeup that it was pronounced a success. The information received from the Genome project will forever transform the healthcare industry. Many believe personalized medicine is the future of medicine, just the next step in the world of human genetics. Genome is the whole entirety of an organism. It is encoded either in DNA or for different viruses in RNA. The genome has the genes and the non coding sequences of DNA and RNA. The prospects of examining a person’s whole genome and make individual health risk predictions and treatment is within reach. Researchers at Mount Sinai School of Medicine along with...
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...Personalized Medicine Pharmacy has been a key component of medicine for generations. From witch doctors providing herbal remedies, to the recent use of pharmacogenomics, medicine has always worked differently for different people. However, new advances in technology and understanding of the human body have allowed humans to leap forward and save lives. Genetic testing can improve the use of prescription drugs in many ways. Prescription drugs do not always work, and can sometimes be toxic to the users. This is due to the differences between different people and the fact that everyone has a different genetic makeup. For example, Her2/neu genes code for a protein receptor, the Her2 receptor, which deals with cell growth and differentiation. Some polymorphisms in the Her2/neu genes can change how some women’s breasts grow, leading to possible tumors. Cancer can also cause mutations, making the Her2/neu genes overactive, leading to tumors. Thus, women with breast cancer are routinely checked for Her2/neu over-activity. Physicians prescribe a drug called Herceptin to these Her2/neu positive patients. Herceptin does not work as well with patients that are Her2/neu negative, and in fact can be toxic to these patients (1). Thus, genetic testing allows us to change treatments in a way that could be life saving. However, genetic knowledge can change a person’s life, either through ability to act preventatively or by paralyzing a carrier with the weight of a decision. Gene...
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...making it possible for medicinal products to become personalized. In this paper I will be explaining how modern genetic technology may lead to personalized medicine; discussing the benefits of personalized medicine; and discussing the drawbacks and limitations of personalized medicine. Explanation of how modern genetic technology may lead to personalized medicine. In order to understand how modern genetic technology may lead to personalized medicine, we need to first understand what personalized medicine is. Personalized medicine is the ability to determine an individual’s unique molecular characteristics and to use those genetic distinctions to diagnose more finely individual’s disease, select treatments that increase the chances of a successful outcome and reduce possible adverse reactions. Personalized medicine is also the ability to predict an individual’s susceptibility to diseases and thus to try to shape steps that may help to avoid or reduce the extent to which an individual will experience a disease. With that being said, the advancement in technology has made it possible for doctors and geneticists use a person’s DNA to find out what kinds of diseases are in their future; thus making it possible for them to make a stepping stone to prevent them. “The completion of the Human Genome Project in 2003 opened the door for better understanding of genetic components of disease that will shape the future practice of medicine. The Human Genome Project detailed the map of our...
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...Research www.renub.com Personalized Medicine Diagnostics (Flow Cytometry, Sepsis Immunos, Routine Coagulation, Psychiatric Disorders, Tumor Markers, Molecular Blood Typing and Other Testing) Market & Forecast Published: June, 2013 Copyright © 2013 Renub Research – All Rights Reserved Personalized Medicine - Market Overview Personalized Medicine is often defined as “the right treatment for the right person at the right time.” Personalized medicine is becoming the place to be in clinical diagnostics as well and slowly becoming the reality of future in the diagnostics industry By Technology Segment - Personalized Medicine diagnostics market is expected to grow with a double digit CAGR for the period of 2013 to 2018. It is expected that personalized medicine diagnostics market by technology is going to double by 2018 from its current market size in 2012. In this segment, Point of Care Testing and Molecular Diagnostics segments control the #1 and #2 positions in 2012. By Diseases Segment - Personalized Medicine diagnostics market is expected to be more than US$ 30 Billion by 2018. Diabetes management test and Cancer management test are the leading market in this segment. Renub Research report entitled “Personalized Medicine Diagnostics (Flow Cytometry, Sepsis Immunos, Routine Coagulation, Psychiatric Disorders, Tumor Markers, Molecular Blood Typing and Other Testing)” report provides a comprehensive analysis of the emerging personalized medicine diagnostic market segments...
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