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Zofran or Ondansteron
Staci J. Tate
Dabney S. Lancaster Community College
Zofran or Ondansteron
Zofran, also known by its generic name of Ondansteron is a medication used to prevent and to treat nausea and vomiting for a variety of different patients. It is used for patients undergoing radiation therapy and in patients with cancer. It is also used as a preventative measure in situations where nausea and vomiting are expected such as after a surgery and is even recommended in cases where the incidence of nausea and vomiting are low. It is available in three different forms, an oral solution, orally disintegrating tablets that are absorbed through saliva, and oral tablets that you take with water. It is to be protected from sunlight, stored at room temperature, and it is to be kept in the wrapper until it is time to take the dose or when given an oral solution, the bottle is to be kept upright at all times. If you miss taking your dose of Zofran it is okay to take it as soon as you remember. Contraindications of this medication include hypersensitivity to ondansteron hydrochloride which is the main ingredient in the drug and in patients taking apomorphine because of the incidence of a loss of consciousness and severe hypotension reported when taking both of these drugs together.
Question One
The website Zofran.org appears more biased in the fact that it says that the effects of Zofran on pregnant women have not been studied efficiently without further explanation and instead of saying some people experience these side effects it just says things like “common possible” and “may occur.” The information on Zofran from the website drugs.com does say that there are no adequate studies on the use of the drug in pregnant women but it also includes that studies were done on pregnant animals using the drug with them having no side effects and gives more information about using it with children and in the geriatric population whereas Zofran.org does not mention the geriatric population at all. It is more unbiased because it shows results and includes studies and provides you with basically any and everything you would ever need to know about Zofran down to the molecular composition and weight.
Question Two
The information provided on Zofran.org is more efficient for a person other than a healthcare provider to read. It is easier for the consumer to understand and even provides a page where you can buy Zofran for a discount with included vendor websites. It would be easier for the consumer to read and understand because it does not have a bunch of big technical words and is less confusing to someone who does not understand chemistry. The information on drugs.com goes in to thorough detail, provide charts, and speaks about trials done on humans and animals of all different types, including information such as how it can adversely affect various body systems. It has too much information for the patient who knows nothing about drugs and the chemistry of them to understand and can definitely be confusing.
Question Three Zofran.org is definitely the website easier to read and would more likely be chosen by the consumer. On drugs.com there is a lot of different information to go through and on Zofran.org it just gives you the basics like your doctor will decide how much you should take. Drugs.com would be a lot harder to read because it even goes into detail about how the medication is supplied and provides information on the studies done in both males and females and the differences that occurred. It would bore the patient uninterested or not educated in the field of Pharmacology.
Question Four
Depending on the patient, I would recommend that my patient first look at the website Zofran.org just to get a general overview of the medication and what it is used for and if he/she still other questions than I would recommend that they go to drugs.com where they can find out basically any and everything they want to about the drug from the pharmacology down to dosage adjustments for patients with renal dysfunction.
References
Last Name, F. M. (Year). Article Title. Journal Title, Pages From - To.
Last Name, F. M. (Year). Book Title. City Name: Publisher Name.

http://www.drugs.com/pro/ondansetron.html
http://www.zofran.org/

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