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Sid In Infants: A Case Study Essay

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This is a case report about about a 10-month-old caucasian infant presenting with chronic diarrhea, hypercalcemia, failure to thrive, and metabolic acidosis. The infant was diagnosed with SID, then prescribed a sucrose-restricted but normal calcium diet regimen to help stop her diarrhea, substantial weight gain, and resolution of hypercalcemia. The purpose of the report is to show how hypercalcemia may complicate neonatal SID and that the presence of both hypercalcemia and chronic diarrhea should suggest SID in young infants.

Like a classic presentation of SID in infants that occurs when they wean from breast milk and begin formula and diet changes, this infant was growing well and thriving until weaned from breast milk when she began to have frequent stools and poor weight gain.

Strength: Unlike the other three studies that did not involve the gold standard of small intestine biopsy specimen to diagnose SID, this infant was diagnosed after multiple small bowel biopsies resulting in abnormal lactase, sucrase, and maltase. …show more content…
Extensive evaluation of her condition failed to identify any abnormality in calcium regulation. There may be roles for chronic metabolic acidosis and dehydration in promoting both increased bone mobilization of calcium and thus increasing the risk of renal deposition. Non-hydrolyzed lactose may also exert a direct enhancing effect on calcium absorption in the ileum. Alternatively, it is possible that both SI and lactase are connected mechanistically to intestinal calcium homeostasis through molecular interactions with calcium transporters. As a result, prolonged periods of diet noncompliance may increase the risk of chronic renal disease secondary to

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