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CHAPTER I INTRODUCTION Upon reading this research paper, efforts to prevent and treat dengue include various means of vector control , a number of novel methods have been used to reduce mosquito numbers with some success including the placement of the guppy or copepods in standing water to eat the mosquito larvae. Attempts are ongoing to infect the mosquito population with bacteria of the Walachia genus , which makes the genetically modified male and there are ongoing programs working on a dengue vaccine to cover all four serotypes. Dengue fever or also known as break bone fever , is an infectious tropical disease caused by the dengue virus . There are many symptoms include fever, headache , muscles and joint paints and a characteristics skin-rashes that is similar to measles . In a small proportion of cases the virus develops into the life threatening dengue hemorrhagic fever, resulting bleeding , low levels of blood platelets and blood plasma leakage or into dengue shock syndrome , where dangerously low blood pressure occurs treatment of acute dengue is supportive , using either oral or intravenous rehydration fusion for ore serve cases . There are ongoing programs working on a dengue vaccine to cover all serotypes . One of the concerns is that a vaccine could increase the risk of severe disease and the most developed is based on a weakened combination of the yellow fever virus and each of the four dengue serotypes. It is hoped that the first products will be commercially. Apart from attempts to control the spread of the aedes mosquito and work t develop a vaccine against dengue , there are ongoing efforts to developed antiviral drugs that would be used to treat attacks of dengue fever and prevent severe complications .

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