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The Tuskegee Syphilis Study

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Tuskegee Syphilis Study was a very controversial research study conducted by the United States Public Health Service in collaboration with the Tuskegee University (then known as the Tuskegee Institute) in Macon County, Alabama between the years 1932 and 1972. The study was named the “Tuskegee Study of Untreated Syphilis in the Negro Male” and the original intent was to study the effects of untreated syphilis on African-American men for a duration of six to nine months and then follow-up with a treatment plan. A total of 600 African American men were enrolled in the study, 399 men with syphilis and 201 men without the infection.

Syphilis is a highly contagious disease caused by the bacteria Treponema pallidum transmitted sexually or congenitally …show more content…
The federal government engaged a panel of experts to evaluate the study and it found out that the study was “ethically unjustified”. Based on the report of the panel, the study was terminated. In the summer of 1973, a class-action suit was filed on behalf of the men against the PHS resulting in nine million dollars being given to the participants as settlement.
The Tuskegee Syphilis Study raised many ethical questions regarding medical research. Is it ok to involve human subjects in medical research? What should be the level of information that should be provided to subjects of the study? Considering the uncertainty of research outcomes, what is the level of risk that the researcher should allow the subjects to take? Is the researcher at liberty to choose one group over the other when administering treatment?
Following the public outcry over the Tuskegee Syphilis Study, the United States congress established a commission which submitted its report called as the Belmont Report in 1979. The Belmont report laid out principles which are considered as ground-rules for modern day medical research. The Federal Government established the Office for Human Research Protections (OHRP). The OHRP ensures the rights of human subjects involved in research in the United …show more content…
Patient rights have been defined and standards have been established for conducting medical research in an ethical manner. The fundamental principle of medical research is Beneficence, which minimizes harm and maximizes benefits. Patient rights such as Right to freedom from harm and discomfort, right to protection from exploitation, Respect for human dignity, right to self determination have been established to protect the research participants. The second principle is Justice which thrives for fair treatment and privacy and confidentiality. These principles are tightly regulated, any violation of these rights for the participants can result in punitive action against the researchers. Finally, informed consent is an important principle for safeguarding participants’ rights. Informed consent means that the participants has all the information about the study, the researchers have explained the risks and benefits involved in the study and that the participants have freely accepted to enroll in the study without any coercion. The participants sign a consent form after they have clearly made a decision to enroll in the

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