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Thyroid Cancer Essay

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Words 1379
Pages 6
Ankur Sandhu
Journal Article on Thyroid Cancer
Classification of thyroid tumors by Mass Spectrometry Imaging
Course: Anatomy and Physiology
November 29th, 2016
Instructor: Mr. Linder

Introduction:
Thyroid is a gland which is located at the base of our neck. It is commonly known as a butterfly shaped gland. In this journal, I will talk about the types of thyroid malignancies and the ways to classify them. Malignancies in thyroid often present as nodules which are solid lumps that can be filled with fluid. Out of all the cancers worldwide, malignant tumors comprise of 1-3 percent of cancers. According to studies 5-10 percent of thyroid nodules result in thyroid malignancies. The majority of thyroid carcinomas originate from follicular epithelial cells. Anaplastic or undifferentiated carcinomas (ATC) are the most aggressive thyroid malignancy known so far.(G.B. Salabè2001)( R.A. DeLellis, R.V. Lloyd, P.U. Heitz, C. Eng 2004)( Y.C. Oertel 2004) http://www.sciencedirect.com October 2016 ) …show more content…
In most cases, Thyroid Cancer can be detected by aspiration of nodules in thyroid through needle. This technology is called fine needle aspiration technology (FNAC). Resected thyroid tissue can be further diagnosed by histopathological intraoperative examination. However, in some cases cytological and histological patterns are ambiguous and proper classification is problematic. Molecular biomarkers can be used to classify the thyroid cancer, which are based on histopathological patterns. The most numerous and advanced studies are based on mutation and gene expression profiling. E. Uyy, V.I. Suica, R.M. Boteanu, D. Manda, A.E. Baciu, C. Badiu, F. Antohe, Endoplasmic reticulum chaperones are potential active factors in thyroid

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