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Xenical Orlistat

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Xenical 120mg capsules When used in obesity Xenical (Zen­nik­al) is a medicine which is used in obesity. Xenical contains orlistat. It is supplied by Roche Products Limited. Your medicine Xenical is used in the treatment of obesity. Xenical prevents your body from absorbing the fat from the food you eat. By reducing the amount of fat which is absorbed, Xenical can help you to lose weight more easily. Do not share your medicine with other people. It may not be suitable for them and may harm them. The pharmacy label on your medicine tells you how much medicine you should use. It also tells you how often you should use your medicine. This is the dose that you and your prescriber have agreed you should use. You should not change the dose of your medicine unless you are told to do so by your prescriber. If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber. When to take your medicine Some medicines work best if they are taken at a specific time of day. Getting the most from your medicine can also be affected by what you eat, when you eat and the times at which you take other medicines. Make sure you follow any specific instructions given to you by your prescriber or that are in the Patient Information Leaflet that comes with this medicine. In the case of Xenical: • Xenical can be taken before, during or up to one hour after each main meal • if you miss your meal or have a meal low in fat, you should not take your dose of Xenical • if you have been advised to take a multivitamin preparation, you should take it at bedtime or two hours after taking Xenical How to take your medicine Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine. In the case of Xenical: • swallow the medicine whole with a glass of water If you are having problems taking this form of Xenical, you should talk to your prescriber or pharmacist. They may be able to give you advice on Provided by www.medicines.org.uk/guides other ways to take your medicine or other preparations that are easier for you to take. Taking too much of your medicine Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. You may need a test to assess the effect of taking extra doses. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice. Contact your prescriber, pharmacist, specialist clinic or NHS Direct on 0845 46 47 for advice. Make sure you take all of your medicine containers with you if you are advised to go to hospital. Stopping your medicine Suddenly stopping your medicine may cause your original condition to return. This is why you must speak to your prescriber if you are having any problems taking your medicine. If you are not having any problems taking this medicine then do not stop taking it, even if you feel better, unless advised to do so by your prescriber. If you are in any doubt, contact your prescriber, pharmacist, specialist clinic or NHS Direct on 0845 46 47. Looking after your medicine The instructions on how you should keep your medicine are on the pharmacy label. You should keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children. In the case of Xenical: • if this medicine comes in a blister pack you should store it below 25°C and store it in the original package to protect it from moisture • if this medicine comes in a bottle you should store it below 30°C and keep the container tightly closed to protect it from moisture You must not take the medicine after the expiry date shown on the packaging. If you have any unused medicine, return it to your pharmacist who will dispose of it safely. Whether this medicine is suitable for you Xenical is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history. Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you: • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine • have liver problems • have kidney problems • are elderly • have chronic malabsorption syndrome • are breast­feeding • have cholestasis • have epilepsy • have hypothyroidism • have risk factors for a reduced volume of fluid in the body Xenical is not used in children. Over time it is possible that Xenical can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Xenical has become unsuitable, it is important that the prescriber is contacted immediately. Side­effects A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks. Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated. Some side­effects may be serious while others may only be a mild inconvenience. Everyone's reaction to a medicine is different. It is difficult to predict which side­effects you will have from taking a particular medicine, or whether you will have any side­effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine. Very common: More than 1 in 10 people who use Xenical • flatulence • headaches • infection of the upper respiratory tract • influenza • lowered blood sugar • oily discharge from the rectum • oily, fatty or liquid stools • passing stools more often than usual • stomach pain and discomfort • sudden urge to pass stools Common: More than 1 in 100 people who use Xenical • distension of the stomach • faecal incontinence • feeling anxious • infection of the lower respiratory tract • irregular menstrual periods • rectal pain and discomfort • soft stools • swelling of the stomach • tiredness • tooth or gum problems • urinary tract infection The frequency of these side­effects is unknown • abnormal laboratory test results • bleeding from the rectum ­ you must tell your prescriber if you get any bleeding from the rectum • diarrhoea ­ if diarrhoea is severe this may lead to a failure of oral contraceptives to work in people who are taking oral contraceptives. The use of an additional method of contraception is recommended • gallstones • gastrointestinal problems such as diverticulitis or pancreatitis • hypersensitivity reactions such as itching, urticaria, skin rashes, angioedema, bronchospasm, or anaphylaxis • increased risk of bone fractures • kidney problems • liver problems ­ some of these liver problems may be fatal or may lead to liver transplantation • skin problems • thyroid problems If you feel unwell or if you have concerns about a side­effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call NHS Direct on 0845 46 47. Taking other medicines If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate. The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be Last updated 17 Jun 13 Copyright © 2010 Datapharm

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Xenical
Xenical 120mg capsules When used in obesity necessary to alter your dose or monitor you more closely. Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions. The following medicines may interact with Xenical: • ciclosporin • acarbose • warfarin • amiodarone • vitamin K • vitamin D • vitamin A • vitamin E • valproate • lamotrigine • iodine salts • levothyroxine • lithium The following types of medicine may interact with Xenical: • antidiabetics • oral anticoagulants • oral contraceptives • antiepileptics • antipsychotics • antidepressants If you are taking Xenical and one of the above medicines or types of medicines, make sure your prescriber knows about it. Complementary preparations and vitamins Medicines can interact with complementary preparations and vitamins. Make sure you tell your prescriber the names of all the complementary preparations and vitamins that you are taking or are planning to take. Your prescriber can then decide whether it is appropriate for you to take combinations that are known to interact. In the case of Xenical: • this medicine may interact with vitamin A, D, E and K If you have been prescribed Xenical you should only take something on the above list on the specific advice of your prescriber or pharmacist. Driving and operating machinery When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely. In the case of Xenical: • this medicine will not affect your ability to drive or operate machinery You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber. Diet Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods. In the case of Xenical: • this medicine may reduce your body's ability to absorb Vitamins D, A, E and K from your food. Your prescriber may advise you to take a multivitamin supplement • you should continue on the diet advised by your dietician or prescriber while taking Xenical. It is recommended to spread your daily intake of fat evenly over three main meals as having a meal high in fat with Xenical will lead to an increase in gastrointestinal side effects You need to make sure that there are enough of these vitamins in your diet. For more information contact your prescriber. Alcohol Alcohol can interact with certain medicines. In the case of Xenical: • there are no known interactions between alcohol and Xenical Family planning and pregnancy Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine. In the case of Xenical: • you should only use this medicine during pregnancy if your doctor thinks that you need it You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy. If the decision is that you should not have Xenical, then you should discuss whether there is an alternative medicine that you could take during pregnancy. Breast­feeding Certain medicines can pass into breast milk and may reach your baby through breast­feeding. In the case of Xenical: • women who are breast­feeding must not use this medicine Before you have your baby you should discuss breast­feeding with your doctor or midwife. If you wish to breast­feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast­feed. You should not stop this medicine without taking advice from your doctor. Ingredients of your medicine Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's taste and appearance and to make it easier to take. Some may be used to prolong the life of the medicine. You should check that you are able to take the ingredients in your medicine, especially if you have any allergies. Xenical contains: • orlistat • microcrystalline cellulose E460 • povidone (E1201) • talc • gelatin • indigo carmine (E132) • titanium dioxide (E171) • sodium starch glycollate (type A) • edible printing ink • black iron oxide • ammonia solution concentrated • potassium hydroxide • propylene glycol • shellac • sodium lauril sulfate If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Xenical before, do not Last updated 17 Jun 13 Copyright © 2010 Datapharm use Xenical. Talk to your prescriber, pharmacist or nurse as soon as possible.

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