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A & P Elephantiasis

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Submitted By ngolbadi
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Explain the three mechanisms for transporting carbon dioxide in the blood. How is most of the CO2 in blood transported? How much do the other mechanisms account for?

2. Background: Elephantiasis is caused by a filarial nematode that infects the lymphatic vessels after an individual is bitten by an infected fly. As you clear the parasite infection, a large amount of debris is left in the lymphatics which leads to a burst of bacterial growth inundating the lymph nodes. In advanced cases complete blockage of the flow of lymph from an appendage by the bacterial overgrowth. Over time the infected patient’s limb distorts to incredible size as it accumulates interstitial fluid that does get returned to the blood. Pressure in the tissues surrounding the vessels in the limb leads to reduced blood flow and opportunistic bacterial infections of the epidermis increase.. The infections leave grey or tan rough patches of scar tissue covering the appendage that now resembles an elephant’s limb - hence the name of the disease.

Your essay prompt: Where did all the fluid come from in the first place??

Explain the forces within and around a capillary that are responsible for the edema characterizing elephantiasis. You should start by explaining the role of the lymphatic system as it pertains to the osmotic balance of the blood, then define net filtration pressure and how it can be interpreted, and describe the different relationships between filtration and reabsorption along a capillary. A complete answer will discuss the movement of fluid across the capillary wall at different points along the entire length of a capillary as well the overall net effect. Be sure to explicitly state how the lymph system and cardiovascular system interact to produce the symptoms of this disease.

H ere are a couple immune essays I have used in the past that are good examples of a possible...

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