...| 2012 | | Leukemia and Lymphoma Society Tawanda Bryant | [Leukemia and Lymphoma Society] | The Leukemia & Lymphoma Society (LLS) is: Cure leukemia, lymphoma, Hodgkin’s disease and myeloma, and improves the quality of life of patients and their families. Providing free information and support services, Leukemia and Lymphoma funds lifesaving blood cancer research around the world. | LEUKEMIA & LYMPHOMA SOCIETY TAWANDA BRYANT 11410 COUNTY ROAD 20 BOLIGEE, AL 35443 (205) 336-9851 tbryant3030@yahoo.com LEADERSHIP and ORGANIZATIONAL MAR12 SEC AA March 9, 2012 INSTRUCTOR: SHAROLYN HERGOTT LEUKEMIA & LYMPHOMA SOCIETY I have picked this organization because my best friend passed away last year with leukemia and I wanted to find out more on this disease and what I can do to help. Been passionate and concern about not only her health but the health of her kids, my research will show why it is important to me as well as others. Having a passion for helping other in any way I can is what I am going for. I also like the face that I can somewhat relate to their illness and pain they endure within their life. I would love to find a quicker cure for these diseases, but I know others are working on something better. Having someone close to you with any type of disease, not just leukemia or lymphoma is hard to take in and understand. Having the ability to communicate, have critical thinking, collaboration, and the ability to problem solve is what I aim...
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...* What Is a Blood Disorder? Bottom of Form Blood disorders are physical conditions that prevent the normal function of blood in the body. A disorder may involve factors that interfere with the production of the individual components found in the blood, such as hemoglobin or blood proteins. The nature of a blood disorder may also include situations where the blood does not coagulate properly, or the blood cells themselves are malformed or infected. There is a wide range of blood diseases known today. Anemia is one of the more common examples of a blood disorder. Sometimes referred to as tired blood, a person who is anemic is likely to have a lack of proteins and other elements in the blood. As a result, the blood cannot carry the needed nutrients to various parts of the body and the individual is likely to feel fatigued more often. Over time, anemia can also have a negative impact on the emotions, as the blood is unable to supply proper nutrition to the brain for the production of chemicals that help to maintain an even mood. Sickle cell anemia is one of the more serious types of anemic blood disorder. In addition to fatigue, a person suffering with this disorder is also likely to experience a great deal of pain. The pain may be localized in one part of the body or migrate to different areas throughout the course of the day. Ad Hemophilia is another relatively common blood disorder. Hemophiliacs suffer with a condition in which the blood lacks the normal ability to coagulate...
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...Kauer,1 Johannes Rainer,3 Reinhard Kofler,3 Andrew Hall,4 Markus Metzler,5 Luder Hinrich Meyer,6 Claus Meyer,7 ¨ Jochen Harbott,8 Rolf Marschalek,7 Sabine Strehl,1 Oskar A. Haas,2 and Renate Panzer-Grumayer1,2 ¨ Cancer Research Institute, St Anna Kinderkrebsforschung, Vienna, Austria; 2St Anna Kinderspital, Vienna, Austria; 3Tyrolean Cancer Research Institute and Biocenter - Division Molecular Pathophysiology, Innsbruck Medical University, Innsbruck, Austria; 4Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom; 5Department of Pediatrics, University of Erlangen-Nuremberg, Erlangen, Germany; 6Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany; 7Institute of Pharmacological Biology/DCAL, Goethe-University, Frankfurt, Germany; and 8Onkogenetic Laboratory, Department of Pediatric Hematology/Oncology, Justus-Liebig-University, Gießen, Germany 1Children’s Approximately 25% of childhood acute lymphoblastic leukemias carry the ETV6/RUNX1 fusion gene. Despite their excellent initial treatment response, up to 20% of patients relapse. To gain insight into the relapse mechanisms, we analyzed single nucleotide polymorphism arrays for DNA copy number aberrations (CNAs) in 18 matched diagnosis and relapse leukemias. CNAs were more abundant at relapse than at diagnosis (mean 12.5 vs 7.5 per case; P .01) with 5.3 shared on average. Their patterns revealed a direct clonal relationship with exclusively new ab- errations at relapse...
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...242 AM Reading Report 1 May 29th, 2014 Paper reviewed: Woyach, J.A. et al. 2014. Resistance mechanisms for the Bruton’s tyrosine kinase inhibitor ibrutinib. NEMJ. DOI: 10.1056/NEJMoa1400029 Summary of paper: Ibrutinib acts as an irreversible inhibitor of Bruton’s tyrosine kinase (BTK) that induces a modest amount of chronic lymphocytic leukemia (CLL) cell apoptosis stopping B-cell receptor signaling and proliferation in vitro. Ibrutinib has been shown to have clinically significant activity in patients with relapsed CLL with 71% of patients having complete or partial response and 15-20% of patients having at least a partial response. Patients treated with Ibrutinib have a 75% progression-free survival rate. This paper investigated possible resistance mechanisms to Ibrutinib associated with mutations in BTK. Mutations were determined using whole-exome sequencing of baseline samples of patients with CLL and compared to whole-exome sequences of the patients after relapse. A cysteine-to-serine mutation in BTK at the biding site was found along with three gain-of-function mutations that are downstream from the BTK binding site that lead to autonomous B-cell receptor activity. Bias of paper: The paper was not biased. Research was funded by Funded by the National Cancer Institute and other institutions. No conflicts of interest were included in this paper. Conclusion supported? Mutations of BTK binding site and B-cell receptor pathways in this study suggest that...
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...Stem Cell Research in Human Transplantation [Name of the Writer] [Name of the Institution] Abstract Skeletal Bone Marrow that is decimated by disease, chemo, or radioactive emission can be refurbished by utilizing stem cell transplants. For certain infectious ailments like leukemia, aplastic anemia, certain inherited body-fluid infections, and some infections of the immune cell, and the stem cells in the skeletal bone marrow do not effectively function the way that it is intended to function. The stem cell is subjected to immunity issues where the recipient body site does not accept the donor cells. This paper will look to enquire the benefits to following stem cell research in human transplantation. Stem Cell Research Introduction Unique functional cells such as for example, a red blood cell start out originally as unspecialized cells known as stem cells. These stem cells have the uncanny ability to keep separating through division and multiplying in culture to produce specialized cell for a specific bodily function. In the context of normal human development, they are best described for their diversity, adaptability and longevity. As the laws of biology dictate, a human being is formed when a sperm cell fertilizing a female egg cell to produce a zygote. The zygote is already specialized in the fact that it is on the way to the formation of a whole individual. Furthermore the zygote, also known as the fertilized egg is tot potent that simply...
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...Ethical Paper Della A. Dalberg HCS/335 March 31, 2014 Ethical health care topics typically become controversial topics that are aimed to think towards a conscience goal. The goal is to help explain the importance of the entire topic, rather than just the cons or, the pros. Ethical health care topics that are controversial happened to help develop personal views that are typically limited by personal beliefs. Currently, an ethical health care dilemma has been breaching media pertaining to the use of HIV and AIDS for cancer. Scientist and researchers in the health care world have successfully manipulated a modified version of HIV. The modified version is injected into the blood-stream to attack cancer cell (The Inquisitr, December 10. 2012). Cures for cancer tend to cause many controversial debates on the ethical standings of what is morally correct (The Inquisitr, December 10. 2012). The modified HIV, will not infect the patient with typical HIV symptoms, however, the modified HIV will act according to the traits in order to become the strongest cell in the human body (The Inquisitr, December 10. 2012). At the Children’s Hospital of Philadelphia, doctors manipulated a seven year old female’s immune system to help direct the cancerous cells. According to The Inquisitr (December 10. 2012), “They took a batch of her own T cells-a type of white blood cell-and genetically engineered them to kill the B cells-another type of white blood cell-responsible...
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...Using Human Cloning for Medical Research The subject of human cloning has many different points of view. The utilization of human cloning for the sake of medical research is a path that we, as guardians of the future, should stand up against in an effort to preserve the human race as we know it today. The topic of cloning has many different terminologies as well as types. What is cloning? Cloning is not limited just to humans but is actually all around us. It exists in nature, animals and humans. Cloning is defined as the creation of a genetically identical copy of an existing human or growing cloned tissue from that individual. This term is generally used to refer to artificial cloning; human clones in the form of identical twins are commonplace, with their cloning occurring during the natural process of reproduction. “Human cloning is the asexual production of a human being whose genetic makeup is nearly identical to that of a currently or previously existing individual” (Chesire et al., 2003, p. 1010). To be successful with cloning, scientists utilize and create “generic” cells that that have the ability to make exact duplicates or copies of themselves indefinitely. This process is known as “stem cell research.” Stem cells are a key element of the different types of cloning and will impact advances in helping to cure many different types of diseases such as Alzheimer’s and Parkinson’s disease, diabetes, spinal cord injury, heart disease, stroke, arthritis, and cancer. Before...
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...Medicinal Cannabis….what’s all the hype? Medicinal Cannabis Jennifer L. Mello COM/156 Abstract I am writing this research paper not just to inform you, but to help educate you. There are many proven scientific trials and methods of medicinal cannabis. The research that I have found has truly enlightened my way of thinking. Segal, Ph.D. (2012), "The Jamestown settlers brought the marijuana plant, commonly known as hemp, to North America in 1611, and throughout the colonial period, hemp fiber was an important export. Indeed, in 1762, 'Virginia awarded bounties for hemp culture and manufacture, and imposed penalties on those who did not produce it.” (Jamestown Settlers Bring Marijuana to North America). Booth (2005). Medicinal Cannabis….what's all the hype? The therapeutic qualities are marvelous. Cannabinoids offer the following for patient’s antipastic, analgesic, antiemetic, neuroprotective, and anti-inflammatory actions. People who suffer from psychiatric diseases have found relief with their conditions ranging from depression, anxiety, bipolar, and similar mood disorders. The National Institute of Health, also known to many people as NIH. This organization states that medical marijuana helps a great deal with chemotherapy, and nausea. Letting the cancer patient consume food. They have also found that people who suffer from epileptic seizures that use medicinal cannabis helps to prevent them altogether. (Potter, 1998). Cancer patients who are going...
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...Cell Phones and Cancer In today's innovative era of technological breakthroughs, we enjoy many benefits of technology, which give us the power to get things done faster, enjoy greater convenience, and have access to wonderful tools that improve all areas of life (Siepmann, 2004). However, there are many concerns that we are paying a price for these benefits-perhaps in the form of cancer. Major concerns arise from the fact that we are increasingly exposed to logarithmically increasing non-ionizing radiation from wireless systems, cell phones, satellite transmissions, electricity transmission, and other products. This paper aims to present a solid argument that cell phones, in particular, may be a cause of cancer. Researchers suggest that high power electrical distribution lines may increase the incidence of certain cancers (Siepmann, 2004). According to the EPA (Environmental Protection Agency) (1990): “In conclusion, the several studies showing leukemia, lymphoma and cancer of the nervous system in children exposed to magnetic fields from residential 60 Hz electrical power distribution systems, supported by similar findings in adults in several occupational studies also involving electrical power frequency exposures, show a consistent pattern of response that suggests, but does not prove, a causal link. Frequency components higher than 60 Hz cannot be ruled out as contributing factors. Evidence from a large number of biological test systems shows that these fields induce...
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...LITERATURE REVIEW FOR ALTERNATIVE AND HOLISTIC MEDICINE Summer Olson University of South Dakota September 5, 2014 Author Note Summer Olson, Department of Health Sciences, University of South Dakota Summer Olson is now a junior at the University of South Dakota. This paper fulfills the critical writing graduate component of the course HSC 440, Major Issues in Health and Human Services. Correspondence concerning this paper should be addressed to Summer Olson, Summer.Olson@coyotes.usd.edu Article # 1 A study by Arvind Chopra (2013) examined how an Ayurvedic medicinal technique compares to modern remedies for osteoarthritis. Dr. Chopra is an associate at the Center for Rheumatic disease where he is a leader in research. The study...
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...Proceedings of the International Conference on Non-Ionizing Radiation at UNITEN (ICNIR 2003) Electromagnetic Fields and Our Health 20th – October 2003 22nd Recent Research on Mobile Phones Effects Dr. Abdullah AlOrainy Inst. of Electronics Research, KACST P. O. Box: 230471, Riyadh 11321, Saudi Arabia E-mail: alorainy@kacst.edu.sa ABSTRACT The use of mobile phones always accompanied by the issue of health implications for human. Previous research studies show no evidence of the impacts of mobile phones to human health. New studies suggest that mobile radiation might double the risk of developing cancer on the side of the head used, increase brain activity, can cause damage to nerves around ears and, more importantly, damages the BBB. Also new research shows that biological effects are possible without any warming of tissues which impose of the current radiation exposure levels. KEYWORDS Mobile Radiation, Health Effects INTRODUCTION There are now about 1 Billion mobile phones in use worldwide, and it is expected to reach 1.6B lines by year 2005. In many countries, penetration rates of more than %50 has been reached. At present, there are approximately 4.5 million GSM subscribers in Saudi Arabia and STC has commissioned Ericsson and Nokia to expand its GSM network to 5.5 million lines (~ %20 penetration rate). This wide use of mobile technology have often raise the question about if there are health implications for human. In fact, there are conflicting reports relating to possible...
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...Stem Cell Research Paper Stem Cell Research Paper Human Biology The human body is capable of many miraculous feats. Every hour, every minute, every second, millions of cells are working to maintain homeostasis within the body. This paper is going to focus on one type of cell in particular, the stem cell. The properties of this little cell are amazing. These unique cells self-regenerate through cell division, and in addition to being unspecialized, have the ability to develop into many different specialized cells of the body. Numerous studies have shown the potential of stem cells to cure cancers, as well as slow or reverse the damages of some neurological disorders, yet stem cell researchers have met with both public and legal resistance during their attempts to show the incredible usefulness of these cells. Therefore, the question is, with stem cell research showing the potential to reverse the damage from or slow the progression of neurological disorders, and possible cures for cancer and other diseases and disorders are the possible benefits too much to ignore? The ability to self-regenerate is one the things that makes the stem cell such an appealing area to study. Most cells and organs in the body do not have the ability to self-regenerate, nor self-repair but stem cells can do both. Stem cells themselves are unspecialized, in that they have so special function (Stem Cell Basics, 2009). Part of the beauty of the stem cell is that through cellular...
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...i DECOCTION OF GUAVA LEAVES AS SUBSTITUTE FOR HYDROGEN PEROXIDE IN REMOVAL OF CALCULUS IN ORAL PROPHYLAXIS A Research Paper made for the Partial Fulfillment of the Requirement in Research II presented to Mrs. Ferrera E. Oira Arbas, Maureen B. Caballero, Amadeo John N. Morales, Ian Paul P. Ramon Teves Pastor Memorial Dumaguete Science High School SY 2013-2014 ii ABSTRACT Calculus is such a burden to many people, it can cause severe oral diseases and most of all, it makes you. Most of the people suffering from calculus go to the dentist for oral prophylaxis. Dentists use hydrogen peroxide to make the calculus soft so it would be easy to get. The researchers made a substitute for hydrogen peroxide and this substitute will make use of one of the gift of nature for us, the healing wonders of herbs. The researchers use boiled guava leaves as substitute for hydrogen peroxide. The researchers chose guava leaves because it contains many antibacterial cell like what is in Hydrogen Peroxide. The researchers have four samples of calculus from different persons, each of the samples were measured and was grouped into two treatments. Each of the treatment has 2 replicates. Every replicate were placed on the treatments together at the same time. The calculus was taken out of the treatment at exactly 4 hours after it was placed on the treatment. The researchers measured their weights, and then data were collected and analyzed thoroughly. The researchers used T-test as their...
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...Scientific research has come a long way since the first use of human embryos to treat and prevent diseases. The polio vaccine was invented in the 1950’s from the use of human fetal kidney cells, fetuses in uteri were used to develop techniques like amniocenteses and improving knowledge about congenital heart disease in the 1970’s, and in the 1980’s the transplantation of fetal tissue into adults to help with serious conditions like, diabetes or Parkinson’s (Gold, 2004). While there has always been concern and controversy over the use of human embryonic cells, today the debate is ethical. This ethical debate lies within the destruction of human embryos in order to use them for medical research. This paper will talk about how two different theories; utilitarianism and relativism view this ethical issue and the problem it presents, as well as my personal views on use of embryonic stem cell research. The theory of utilitarianism determines what is best by looking at the results of an act. According to Mosser (2010, section 1.7), “utilitarianism argues that, given a set of choices, the act we should choose is that which produces the best results for the greatest number affected by that choice.” When looking at the use of embryonic stem cells for research, utilitarianism looks at the end result. Embryonic stem cells have the potential to save lives by curing diseases and through the use of transplantation. While some utilitarianism’s may still view the destruction of these cells as the...
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...Chapter 1 The Problem and Its Setting Introduction Thrombocytopenia or abnormally low platelet counts in the body are typically caused by genetic disorder or fatal diseases. This condition may result from thromboembolic or hemorrhagic complications caused by heparin as well as from various diseases states such as chronic liver disease and dengue hemorrhagic fever. In most rural areas a health care institution is often inaccessible and most patients cannot afford high cost medication. Henceforth, herbal medicines are often used as an alternative treatment. Inadequacy of providing supportive treatment to correct the decrease of platelet is fatal to patients. Thus, several decoctions of herbal plants are purportedly used to improve platelet count. Recently, the mortality rate in heparin – induced thrombocytopenia (HIT) has been reported as high as 20% (Greinacher & Lubanow, 2003). Retrospective data shows that up to 8% of heparinized patients will develop the antibody associated with HIT and that approximately 1–5% of patients on heparin will progress to develop HIT with thrombocytopenia suffering from venous and/or arterial thrombosis in at least one-third of cases (Warkentin et al., 1998). Heparin – induced thrombocytopenia (HIT) is a potentially devastating immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin. Despite thrombocytopenia, bleeding is rare; rather, HIT is strongly associated with...
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