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Biology of Organisms Tutorial 3

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Tutorial 3
Bio 207
1) Glomerular filtration rate (gfr) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the tiny filters in the kidneys each minute. These tiny filters are called glomeruli.
Vasa recta is the hairpin shaped capillaries that serve the long loop of henle of juxtamedullary nephrons. Each ascending porion of the vasa recta lies next to the descending portion of a loop of henle and vice versa
Although the loop of henle and the vasa recta do not exchange materials directly, they function together as a counterpart of a countercurrent system that enhances nephron efficiency.
(source Campbell, Reece, et al., Biology 8th edition. 2009.
Renal clearance is a measurement that allows one to analyze the activity of the kidney. Renal clearance = urine concentration (M) x urine flow rate (ml/min)/plasma concentration (M)= UV/P RCGFR=secretion RC=GFR = nothing is secreted or absorbed.
(source: www.austince.edu/emeyerthclearancehtm.htm)
Single effect is produced by the use of metabolic energy between adjacent parts of the two oppositely flowing fluid streams in a counter current multiplier system (Source: Hill, Wyse and Anderson, Animal Physiology 2012)
2) Blood enters the kidneys through the bowman’s capsule where it enters a cluster of blood capillaries called the glomerulus. Fluid is driven through a filter in the glomerulus into the capsule’s lumen by the hydrostatic pressure of the blood. The fluid that accumulates in the lumen is called the capsular fluid. However large organic molecules of the size of 10,000 daltons are too large to enter the lumen and remain in the blood plasma. Molecules like glucose however enter capsular fluid and form the primary urine. Solutes and water flow down from the lumen, down the tubule of the nephron and much is reabsorbed here. Solutes like glucose and

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