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Bubble Kid Research Paper

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Bubble kid [18]:

Nina Graeme was 5 weeks old baby. Her mother, Aga Warnell, observed something wrong with her baby, she wasn't hungry in the way her other daughters had been. Within weeks, Nina became very ill, says her father, Graeme. She was admitted to hospital with a rotavirus infection. Then she picked up pneumonia. In the hospital the doctors revealed a condition called (severe combined immunodeficiency or SCID). She was born with immune system defects due to a genetic defect.

In this condition, the patient must live in a sterile environment. The doctors said to her father that she probably wasn't going to survive. Nina had a disorder called (ADA_SCID) this condition is caused by a genetic defect in the gene coding for adenosine deaminase enzyme . This enzyme usually dispatches a toxic molecule from WBCs. In its absence the toxin builds up, killing defending cells. The therapy began in April, first stem cells from Nina's bone marrow were harvested, then worked on ADA gene, finally these cells were injected back in. In August her WBCs count had nearly doubled. After one an half year of gene therapy, Nina was a happy little girl had a functioning immune system. …show more content…
This is the autopsy photo showing some of the characteristic finding of GVH, i.e. edema, hemorrhagic skin lesions due to DIC, and abdominal organ

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