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Central Diabetes Insipidus Research Paper

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Central diabetes insipidus is a condition that does not related to diabetes mellitus, although it has similar symptoms such as extreme thirst and increase urination, they are not related. Central diabetes insipidus is a disease in which the posterior pituitary does not release adequate amount of ADH hormone also known as vasopressin. ADH is released by the pituitary gland and helps prevent water loss. The effect of polyuria caused from this disease causes excessive thirst. What will be discussed is the causes, symptoms, diagnosis, pathology, and treatment of central diabetes insipidus. Central diabetes insipidus can be caused by damage of the hypothalamus, unknown, or genetic. Damage or injury can be due to surgery, tumor, or head trauma. There have been cases that it is unknown of what caused this disease. Also, it is rare for this disease to be caused because of genetic defects. The central nervous system may inhibit the secretion of the ADH …show more content…
Urine samples are used to test urine concentration to check if concentration is high or low. If the concentration is low, it indicates there is a high amount of water compared to the other substances in the urine. Another test is a water deprivation test. This test will not allow the patient to drink fluids for several hours and healthcare provider will measure changes in the urine output and concentration to check if the kidneys are working properly. The amount of urine for a normal person should decrease, but a person’s urine output with diabetes insipidus increases. Blood tests also check for sodium and glucose levels in the plasma. High levels of sodium and low levels of glucose are indicators of diabetes insipidus. Lastly, an MRI of the head to look for any anomalous matter in the brain near the hypothalamus and the pituitary gland will help determine whether a person is diagnosed with this

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