...them to invest in these new markets Global Pharmaceutical Market The pharmaceutical market was $ 820Bn in Other Patented 86% 83% 81% 79% 2009, growing at a CAGR of 9% over 200309 Generics is growing at double the rate of the Generics 2004 2006 2008 2010E total industry (18% CAGR), while Patented drugs market is growing at 7% India 1% Geographical Market Share Middle Africa 1% East 1% CIS 2% Others 12% US 42% Top 10 countries account for 73% of sales US accounts for 42% of the world sales While the US sales are growing at only 1-2% CAGR, growth in emerging markets is over 10% Latin America 6% South East and East Asia 6% EU 29% Source: Centrum Research Report on Pharma Industry 2009; 2 Key Growth Drivers for Global Pharmaceutical Market 1 Sluggish Growth in Mature Markets Economic slowdown leading to reduced healthcare spending Top brands’ patent expiries and very few new product launches Decentralization of government healthcare budgets. High healthcare expenditure by government 2 Faster Growth in Emerging Markets Broader public and private healthcare funding Greater access to, and demand for, innovative medicines 250 200 150 100 50 0 3 Pressure on healthcare budgets worldwide More doctors prescribing Generic Drugs Huge generics future outlook $ 224 Bn drugs coming off patent Declining Patented Drugs Sales & Rising Generics Acceptability Cost advantage over Branded...
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...Introduction: Insulin resistance is associated with type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), both independently and in association with the metabolic syndrome. Impaired insulin sensitivity has been documented in those known to be at risk for diabetes, such as normoglycemic first-degree relatives of people of T2DM, and women with history of gestational diabetes. Although present in most people who developed T2DM, insulin resistance is generally present for many years before changes in blood glucose concentrations are evident. Despite possible influences from genetic and perinatal factors, diet and physical activity are likely to have greater and overriding influence in generation of the metabolic syndrome and T2DM. Dietary intakes of vegetable fat, polyunsaturated fatty acid, dietary fiber (particularly cereal fiber), magnesium, and caffeine are significantly inversely correlated and intakes of trans fatty acid and heme-iron, glycemic index, and glycemic load are significantly positively correlated with the incidence of type 2 diabetes (Murakami K et al J Nutr Sci Vitaminol (Tokyo) 2005; 51:292-310). Studies have shown a significantly decreased risk for T2DM with the higher consumption of grain (particularly whole grain), and significantly increased risk with processed meat consumption (J Nutr Sci Vitaminol (Tokyo) 2005; 51:292-310). Increased obesity is associated with insulin resistance. Other important factors contributing to insulin resistance include...
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...Partnering with Industry for a Computer Science and Engineering Capstone Senior Design Course Ken Christensen[1], Dewey Rundus1, and Zornitza Genova Prodanoff1 1 2 Abstract A capstone design course is an important component of the senior year curriculum for engineering students and plays a key role in achieving departmental ABET EC 2000 outcomes. In the Department of Computer Science and Engineering at the University of South Florida, we have partnered with industry to have students work in teams on industry-contributed “real world” projects. Industry partners contribute projects, mentor students, give a guest lecture, and provide the opportunity for students to present their project at the industry site. Students work on projects in teams and are given milestones and schedules to follow. The milestones include formal requirements, specifications and design, prototype demonstration, test plan, and final project delivery and presentation. The final presentation includes a project demonstration, user documentation, press release, and a poster that is permanently displayed in the department seminar room. The course includes formal lecture and reading assignments on the development process. A midterm exam covers these topics. Soft topics include discussions on working in teams. Our industry partners stress the importance of students being able to work well in teams. We hope that our experience can serve as a guide for other engineering departments considering...
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...Journal of Controlled Release 113 (2006) 189 – 207 www.elsevier.com/locate/jconrel Review Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective D. Venkat Ratnam, D.D. Ankola, V. Bhardwaj, D.K. Sahana, M.N.V. Ravi Kumar ⁎ Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Phase-X, S.A.S. Nagar, Mohali, Punjab, India - 160062 Received 31 January 2006; accepted 26 April 2006 Available online 13 May 2006 Abstract Antioxidants are emerging as prophylactic and therapeutic agents. These are the agents, which scavenge free radicals otherwise reactive oxygen species and prevent the damage caused by them. Free radicals have been associated with pathogenesis of various disorders like cancer, diabetes, cardiovascular diseases, autoimmune diseases, neurodegenerative disorders and are implicated in aging. Several antioxidants like SOD, CAT, epigallocatechin-3-O-gallate, lycopene, ellagic acid, coenzyme Q10, indole-3-carbinol, genistein, quercetin, vitamin C and vitamin E have been found to be pharmacologically active as prophylactic and therapeutic agents for above mentioned diseases. Antioxidants are part of diet but their bioavailability through dietary supplementation depends on several factors. This major drawback of dietary agents may be due to one or many of the several factors like poor solubility, inefficient permeability, instability due to storage of food, first pass effect and GI degradation. Conventional...
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... electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Printed in the United States of America. Printed simultaneously in Canada. Many of the designations used by manufacturers and sellers to distinguish their products are claimed as trademarks. Where those designations appear in this book, and AddisonWesley was aware of a trademark claim, the designations have been printed in initial caps or in all caps. MATLAB is a registered trademark of The MathWorks, Inc. Library of Congress Cataloging-in-Publication Data Passino, Kevin M. Fuzzy control / Kevin M. Passino and Stephen Yurkovich. p. cm. Includes bibliographical references and index. ISBN 0-201-18074-X 1. Automatic control. 2. Control theory. 3. Fuzzy systems. I. Yurkovich, Stephen. II. Title. TJ213.P317 1997 629.8’9--DC21 97-14003 CIP Instructional Material Disclaimer: The...
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...2014-2015 Undergraduate Academic Calendar and Course Catalogue Published June 2014 The information contained within this document was accurate at the time of publication indicated above and is subject to change. Please consult your faculty or the Registrar’s office if you require clarification regarding the contents of this document. Note: Program map information located in the faculty sections of this document are relevant to students beginning their studies in 2014-2015, students commencing their UOIT studies during a different academic year should consult their faculty to ensure they are following the correct program map. i Message from President Tim McTiernan I am delighted to welcome you to the University of Ontario Institute of Technology (UOIT), one of Canada’s most modern and dynamic university communities. We are a university that lives by three words: challenge, innovate and connect. You have chosen a university known for how it helps students meet the challenges of the future. We have created a leading-edge, technology-enriched learning environment. We have invested in state-of-the-art research and teaching facilities. We have developed industry-ready programs that align with the university’s visionary research portfolio. UOIT is known for its innovative approaches to learning. In many cases, our undergraduate and graduate students are working alongside their professors on research projects and gaining valuable hands-on learning, which we believe is integral...
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...Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com.uk. You may also complete your request on-line via the Elsevier homepage (http://elsevier.com), by selecting “Customer Support” and then “Obtaining Permissions.” Recognizing the importance of preserving what has been written, Elsevier prints its books on acid-free paper whenever possible. Library of Congress Cataloging-in-Publication Data Rao, Madanmohan. KM tools and techniques : practitioners and experts evaluate KM solutions / Madanmohan Rao. p. cm. Includes bibliographical references and index. ISBN 0-7506-7818-6 (alk. paper) 1. Knowledge management. 2. Organizational learning. 3. Knowledge management—Data processing. 4. Management information systems. 5. Information resources management. 6. Database management. I. Title Knowledge management tools and techniques. II. Title. HD30.2.R356 2004 658.4¢038—dc22 2004050698 British Library...
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...SU S AIN T ABI LI I M PA C T E EC ON OMIC S O CI A L & EN D R . R E D D Y ’ S L A B O R AT O R I E S L I M I T E D | A N N U A L R E P O R T | 2 0 0 9 – 1 0 RO VI V NM EN TA L • T Y • TI SI PO C R E AT I N G A C ONTENTS 24 MANAGEMENT DISCUSSION AND ANALYSIS 42 BOARD OF DIRECTORS 45 MANAGEMENT COUNCIL 72 DIRECTORS’ REPORT 2 CHAIRMAN’S LETTER 46 CORPORATE GOVERNANCE 89 IGAAP STANDALONE FINANCIALS 4 KEY HIGHLIGHTS 60 ADDITIONAL SHAREHOLDERS’ INFORMATION 70 FIVE YEARS AT A GLANCE 141 IGAAP CONSOLIDATED FINANCIALS 6 THE DNA OF SUSTAINABILITY 187 EXTRACT OF IFRS CONSOLIDATED FINANCIALS 190 STATEMENT PURSUANT TO SECTION 212 OF THE COMPANIES ACT, 1956 191 INFORMATION ON THE FINANCIALS OF SUBSIDIARY COMPANIES 192 NOTICE OF ANNUAL GENERAL MEETING 14 HUMAN RESOURCES 71 RATIO ANALYSIS 16 SAFETY, HEALTH AND ENVIRONMENT 18 CORPORATE SOCIAL RESPONSIBILITY 2 | S U S TA I N A B I L I T Y — C R E AT I N G A P O S I T I V E E C O N O M I C , S O C I A L A N D E N V I R O N M E N TA L I M PA C T CHAIRMAN’S LETTER 2009-10 has been a satisfactory year for your Company. Let me start with the financial results. Consolidated revenues for 2009-10 was Rs. 70,277 million. Excluding revenues from sumatriptan — your Company’s Authorized Generic version of Imitrex® which was launched in 2008-09 — revenue grew by 9%. In US dollar terms, 2009-10 revenue was US$ 1.56 billion. I am...
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...DePauw University Boston Burr Ridge, IL Dubuque, IA Madison, WI New York San Francisco St. Louis Bangkok Bogotá Caracas Lisbon London Madrid Mexico City Milan New Delhi Seoul Singapore Sydney Taipei Toronto McGraw-Hill Higher Education A Division of The McGraw-Hill Companies MODERN ANALYTICAL CHEMISTRY Copyright © 2000 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States of America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. This book is printed on acid-free paper. 1 2 3 4 5 6 7 8 9 0 KGP/KGP 0 9 8 7 6 5 4 3 2 1 0 ISBN 0–07–237547–7 Vice president and editorial director: Kevin T. Kane Publisher: James M. Smith Sponsoring editor: Kent A. Peterson Editorial assistant: Jennifer L. Bensink Developmental editor: Shirley R. Oberbroeckling Senior marketing manager: Martin J. Lange Senior project manager: Jayne Klein Production supervisor: Laura Fuller Coordinator of freelance design: Michelle D. Whitaker Senior photo research coordinator: Lori Hancock Senior supplement coordinator: Audrey A. Reiter Compositor: Shepherd, Inc. Typeface: 10/12 Minion Printer: Quebecor Printing Book Group/Kingsport Freelance cover/interior designer: Elise Lansdon Cover image: © George Diebold/The Stock Market Photo research: Roberta Spieckerman Associates...
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...Q: There is a toy train that can make 10 musical sounds. It makes 2 musical sounds after being defective. What is the probability that same musical sound would be produced 5 times consecutively? ( 1 of _____) ? Answer: 1/2 * 1/2 * 1/2 * 1/2 * 1/2 = 1/32 32 will be the answer. QAlok is attnding a workshop "how to do more with less" and todays theme is working with fewer digits. The speakers discuss how a lot of miraculous mathematics can be achieved if mankind (as well as womankind) had only worked with fewer digits. The problem posed at the workshop is :"how many 7 digit mnumners can be formed using the digits 1,2,3,4,5 (but with repetetion) tha are divisible by 4? Can you help alok to find answers? 15625 6250, 19532 19531 Q Peter and Paul are two friends. The sum of their ages is 35 years. Peter is twice as old as Paul was when Peter was as old as Paul is now. What is the present age of Peter? Answer: 20 years. Q The ages of two friends is in the ratio 6:5. The sum of their ages is 66.After how many years will the ages be in the ratio 8:7? Answer: 12 years. Q (There was a long story, I'll cut short it). There are 5 materials to make a perfume: Lilac, Balsalmic, Lemon, Woody and Mimosaic. To make a perfume that is in demand the following conditions are to be followed: Lilac and Balsalmic go together. Woody and Mimosaic go together, Woody and Balsalmic never go together. Lemon can be added with any material. (Actually they had also mentioned how much amount of one...
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...Transforming Lives Communities The Nation …One Student at a Time Disclaimer Academic programmes, requirements, courses, tuition, and fee schedules listed in this catalogue are subject to change at any time at the discretion of the Management and Board of Trustees of the College of Science, Technology and Applied Arts of Trinidad and Tobago (COSTAATT). The COSTAATT Catalogue is the authoritative source for information on the College’s policies, programmes and services. Programme information in this catalogue is effective from September 2010. Students who commenced studies at the College prior to this date, are to be guided by programme requirements as stipulated by the relevant department. Updates on the schedule of classes and changes in academic policies, degree requirements, fees, new course offerings, and other information will be issued by the Office of the Registrar. Students are advised to consult with their departmental academic advisors at least once per semester, regarding their course of study. The policies, rules and regulations of the College are informed by the laws of the Republic of Trinidad and Tobago. iii Table of Contents PG 9 PG 9 PG 10 PG 11 PG 11 PG 12 PG 12 PG 13 PG 14 PG 14 PG 14 PG 14 PG 15 PG 17 PG 18 PG 20 PG 20 PG 20 PG 21 PG 22 PG 22 PG 22 PG 23 PG 23 PG 23 PG 23 PG 24 PG 24 PG 24 PG 24 PG 25 PG 25 PG 25 PG 26 PG 26 PG 26 PG 26 PG 26 PG 26 PG 27 PG 27 PG 27 PG 27 PG 27 PG 27 PG 28 PG 28 PG 28 PG 28 PG 28 PG 33 PG 37 Vision Mission President’s...
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...Essays on Productivity Analysis in the Canadian Tourism and Hospitality Industries by Xiaofeng Li A Thesis presented to The University of Guelph In partial fulfilment of requirements for the degree of |Doctor of Philosophy in Economics Guelph, Ontario, Canada © Xiaofeng Li, December, 2011 ABSTRACT ESSAYS ON PRODUCTIVITY ANALYSIS IN THE CANADIAN TOURISM AND HOSPITALITY INDUSTRIES Xiaofeng Li University of Guelph, 2011 Advisor: Professor David M Prescott This thesis is to investigate the relationship between the productivity in the Canadian tourism and hospitality industries and workforce characteristics, human resources management practice, technology change. The productivity analysis is conducted with different measures of productivity, such as labour productivity and total factor productivity. The first chapter is to calculate labour productivity using the Canadian National Tourism Indicator (NTI) and the Canadian Human Resource Module of Tourism Satellite Account (HRM) for six tourism industries during the period 1997-2008 and to estimate an econometric model of labour productivity. Labour productivity is found to increase with the capital labour ratio, the proportion of part-time hours, the share of immigrant workers and by the proportion of the most experienced workers. The second chapter decomposes the total factor productivity growth for the Canadian tourism/hospitality industries with dynamic factor demand models which is estimated with nonlinear Full Information...
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...Profit after Tax (PAT)2 grew by 45% to Rs. 15.3 billion. ¥ Diluted Earnings per Share (EPS) increased from Rs. 64.9 in FY2011 to Rs. 83.8 in FY2012. I am particularly delighted by four developments. First, your Company succeeded in yet another blockbuster generic launch in the USA under 180days marketing exclusivity. Dr. Reddy’s launched olanzapine 20 mg tablets, the generic version of the brand Zyprexa®. Olanzapine is used to treat schizophrenia and bipolar disorder. This product has added around USD 100 million to your Company’s revenues for FY2012. Second, the biosimilars business continues along its impressive growth path. In my letter to you last year, I had discussed the critical importance of developing biosimilars in the years to come. I am happy to note that your Company’s global biosimilars business grew by 45% over last year and recorded sales of USD 26 million. Today, the biosimilars portfolio of Dr. Reddy’s constitutes (i) filgrastim, (ii) peg-filgrastim, (iii) rituximab and (iv) darbepoetin alfa, which have commercial presence in 13 countries among emerging markets. These are helping to treat patients suffering from cancer — and at prices that are significantly more affordable than the corresponding innovator drugs. Soon, I expect to see Dr. Reddy’s biosimilars entering developed markets. Third, as a scientist-entrepreneur, I am pleased with the steady growth in your Company’s 1 EBIDTA and PAT are adjusted for any one time non-recurring items. 2 D R . R E D D...
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...by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Lippincott Williams & Wilkins at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at permissions@lww.com, or via website at lww.com (products and services). 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging-in-Publication Data McCall, Ruth E., author. Phlebotomy essentials / Ruth E. McCall, Retired Director of Phlebotomy and Clinical Laboratory Assistant Programs, Central New Mexico Community College, Albuquerque, New Mexico, Cathee M. Tankersley, MT(ASCP), President, NuHealth Educators, LLC, Faculty, Emeritus, Phoenix College, Phoenix, Arizona. — Fifth Edition. p. ; cm. Includes...
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...Annual Report 2014-15 Infosys Annual Report 2014-15 Narayana Murthy A tribute to our founders Nandan M. Nilekani S. Gopalakrishnan K. Dinesh The year 2014 was a milestone in our Company's history, when we bid farewell to three of our founders who held executive positions in the Company during the year – Narayana Murthy, S. Gopalakrishnan and S. D. Shibulal. Narayana Murthy stepped down as the Chairman of the Board on October 10, 2014. His vision, leadership and guidance have been an inspiration to Infosys, the Indian IT industry and an entire generation of technology entrepreneurs. He propelled the Company into accomplishing many firsts and in setting industry benchmarks on several fronts. He espoused the highest level of corporate governance standards that have defined Infosys over the years and made us a globally respected corporation. Between June 2013 and October 2014, he guided the Company through a period of stabilization and leadership transition. S. Gopalakrishnan stepped down as Vice Chairman of the Board on October 10, 2014. Kris, as he is popularly known, served the Company in several capacities over the last 33 years. As the Chief Executive Officer between 2007 and 2011, he steered the Company at a time when the world was faced with economic crises. Ranked as a global thought leader, Kris has led the technological evolution of the Company. S. D. Shibulal stepped down as the Company's Chief Executive Officer on July...
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