The Columbian Exchange was a major historical event because it had both a positive and negative impact on the world. Major positive consequenses that resulted from the Columbian Exchange was that Columbus was being very generous towards the native Americans by giving them iron swords and goods for the native Americans. A major negative consequenses that resulted from the Columbian Exchange was that when Columbus got the native Americans to trust him he enslaved them and he had them enslaved until most of them died then he enslaved Africans. In the exchange there were many items taken from the Americas (New World) to Europe (Old World) that people of those countries were treated unfairly too and there were a lot of diseases in america at that