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Comunication

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Hypertension complicates up to 15% of pregnancies, with pre-eclampsia affecting 2–3%. Pre-eclampsia is defined as a multisystem disorder characterised by raised blood pressure and proteinuria. Pre-eclampsia is a condition in pregnancy involving high blood pressure and protein in the urine. Most women with mild pre-eclampsia give birth without problems. However, severe pre-eclampsia can cause major problems with the functioning of the liver, kidneys and blood clotting. These symptoms are late manifestations of a disease process that is initiated in early pregnancy and is the major cause of maternal mortality and morbidity (MORLEY 2004)
The purpose of this literature review is to critically analyse the research available for the use of aspirin in the prevention of pre-eclampsia. However it was difficult to find the relevant articles that related to only the use of aspirin and not a combination of aspirin and other hypertension reducing medication. Also a lot of evidence pointed to the administration of magnesium sulphate based medication working in combination with aspirin or aspirin use in IVF conception methods.
The search for relevant articles began with a search in Pub Med .Using the words, “Pre- eclampsia AND aspirin”, gave 494 results. Limitations were then applied to narrow the search. Firstly the search was narrowed to relevant article published in the last 5 years which reduced the finding to 88. Then only relevant articles in relation to the human’s species were applied and this reduced the number of articles to 77. When the search was limited to randomised controlled trials only this left only 4 relevant articles. However 3 of these studies did not apply to the research question as they were to do with the use of aspirin in IVF conceptions. These articles were disregarded from the other article. Therefore one relevant study was found in this search....

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