...gyeoun eoneu nal ne nunmureul dakka jul [All] Geureon han saram doel su itdamyeon [Baekhyun] Eodideun cheongugilteni [D.O] Neol saranghage dwaebeorin nan ije deo isang Doragal goshi eobseoyo nalgaereul geodwogasyeotjyo (oh no) [Baekhyun] Yeongwonhan sarmeul irheotdaedo haengbokhan iyu [Baekhyun/D.O] Naui yeongwon ijen geudaeinikka [Baekhyun/Suho] eternally love [All] Neoui sesangeuro [Baekhyun] yeorin barameul tago, yeah [All] Ne gyeoteuro [Suho] eodieseo wannyago, from you [D.O] Haemarkge mutneun [Suho] oh [D.O] nege bimirira malhaesseo, oh [All] Manyang idaero hamkke georeumyeon [D.O] Eodideun cheongugilteni Gregor Mendel was born into an ethnic German family in Heinzendorf bei Odrau, Austrian Silesia, Austrian Empire (now Hynčice, Czech Republic), and was baptized two days later as Johann. He was the son of Anton and Rosine (Schwirtlich) Mendel, and had one older...
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...MENDELIAN GENETICS DEFINITION OF TERMS * Genetics – the study of heredity and variation * Heredity – the transmission of traits from one generation to another, from parents to offspring; the protoplasmic continuity between parents and offspring * Variation – any difference existing between individuals of the same species * Chromosome – rod-shaped body in the nucleus of eukaryotes and prokaryotes that contains the hereditary units or genes seen particularly during cell division * Gene – the unit or heredity occupying a particular location on the chromosome and passed on to offspring * Locus – the location of a gene on a chromosome * Diploid – the 2N number of chromosomes; twice the number of chromosomes found in gametes * Haploid – the N number of chromosomes; half the diploid number; the number characteristic of gametes that contain only one set of chromosomes * F1 generation – first filial generation; the first-generation offspring of a genetic cross that has at least two generation * F2 generation – second filial generation; the second-generation offspring of a genetic cross * Homozygous – a pair of similar of like genes for any one character * Heterozygous – a pair of contrasting traits of two kinds of genes * Genotype – the particular genes of an individual that determine a specific trait * Phenotype – the outward appearance of an organism, caused by genetic and environmental influences * Allele –...
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...Heredity Heredity is the transmission from one generation to the next of factors that determine the traits of offspring. Although successful breeding of plants and animals was practiced by humans long before modern civilizations were established, there is no evidence that these early people understood the nature of hereditary factors or how they are transmitted through reproduction. EARLY HISTORY One of the early Greek philosophers, Pythagoras (582-509 BC), postulated that all traits of an offspring are derived solely from its father's semen. Aristotle thought that females also produce semen and that the embryo is formed by a fusion in the uterus of both types of semen. He further postulated that both male and female semen are produced by the body's blood. Leeuwenhoek Until the 17th century, European medical schools taught that hereditary factors in the semen were derived from vapors emanating from each body organ. However, Anton van LEEUWENHOEK observed human semen through his microscope and reported finding "animalcules." It became generally accepted that sperm were the actual carriers of hereditary factors from males to their offspring. Other biologists studied the ovaries of animals, noted the presence of swollen bodies--which they correctly assumed contained eggs--and hypothesized that these eggs were also units of transmission of hereditary factors. Epigenesis Some biologists of the 17th and 18th centuries believed that they saw miniature individuals...
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...Mendel’s “First Law”: Observing Anthocyanin in Brassica rapa Abstract The foundation of genetics lies with the principles that Gregor Mendel outlined after his experiments with pea plants where he discovered the relationship between physical characteristics, or phenotype, and genetic traits, or genotype. This experiment aimed to reproduce Mendel’s results with the Brassica rapa plant, noted for it’s fast generation time, and anthocyanin, a purple pigment that can be visually tracked through subsequent generations. It is important for experiments resulting in scientific discovery to be replicable and peer reviewed. Since Mendelian genetics are the foundation of scientific education, including answering questions about evolution and heredity of beneficial or fatal genes, his experiment is a valid and important choice. The hypothesis was that the presence of anthocyanin in Brassica rapa follows Mendel’s laws. By germinating the P1 generation and creating the F1 and F2 generations through pollination the hypothesis was tested. The experimental hypothesis was accepted with ------ error and the null hypothesis that these results were due to chance was rejected. Introduction A phenotype provides a clear visual cue for examining the inheritance pattern of genotypes and whether or not these patterns follow Mendelian genetic principles. Gregor Mendel is someone who is often referred to as the “father of genetics,” and discovered important theory pertaining to heredity. He did this...
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...Why am I having this test? TORCH is a blood test used to check for several infectious diseases that can cause illness in pregnant women and may cause birth defects in babies. TORCH stands for the different infections the test screens for, which are: Toxoplasmosis. Rubella. Cytomegalovirus (CMV). Herpes simplex virus (HSV). Other infections, such as hepatitis B, HIV (human immunodeficiency virus), human parvovirus, enterovirus, Epstein-Barr virus, syphilis, parvovirus B19, or chicken pox (varicella-zoster virus). You may have the TORCH test done if you are a pregnant woman and your health care provider thinks you might have one of these infections. These infections in a pregnant woman can cause birth defects in the baby. What is being tested? The TORCH test checks for antibodies to these infections. Antibodies are a type of cell that is part of the body's disease-fighting (immune) system. After you get an infection, your body makes antibodies that stay in your body after you recover and protect you from getting the same infection again. The TORCH test checks for two types of antibodies: Immunoglobulin M (IgM). Immunoglobulin G (IgG). What kind of sample is taken? A blood sample is required for this test. It is usually collected by inserting a needle into a blood vessel. How are the results reported? Results will be reported as either positive or negative for either type of antibody. A false-positive result can occur. A false positive is incorrect because it means that a condition...
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...In the 19th century Gregor Mendel started to recognize inheritances or traits passed from parents to offspring in a very consistent pattern. Thanks to new technology in the 1940s and the 1950s like higher powered microscopes scientists could see what they could never see before. They discovered chromosomes and found that they were made out of something called DNA as well as proteins. Further experiments led them to realize that DNA held the code of life. Soon enough scientists started asking what DNA was made of and why it is so important. What they discovered was that DNA consists of four nitrogenous bases called adenine, thymine, cytosine, and guanine. Scientists still wanted to learn how all living things in this world could be created by...
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...or autosomal trait? Introduction: Heredity is the study of acquiring traits by birth. A genotype is the alleles of an organism. A phenotype is the characteristics of an organism. Homozygous means having two identical alleles of a gene. A dominant allele is an allele that has the same effect on the phenotype whether it is present in the homozygous or heterozygous state. A recessive allele is an allele that only has an effect on the phenotype when present in the homozygous state. Heterozygous means having two different alleles of a gene. A carrier is an individual that has one copy of a recessive allele that causes genetic disease in individuals that are homozygous for this allele. We are going to do an experiment similar to what Gregor Mendel did with pea plants where we observe 3 generations and record the ratios of the phenotypes. The P generations were selected at the company that bred the flies for us (Carolina Biological). The P generation is purebred for their particular phenotype (Homozygous). The day that they were placed in the vials is marked on the vials, as well as the phenotypes of the p generation. After 2 weeks of breeding and laying eggs, the P generation was removed and the vials were shipped. The flies that you are working with today are the F1 generation. Then we selected 5 male and females flies and placed them in a vial with culture medium. After about 10 days we will remove the F1 flies and count the F2 flies. From that data we will determine if the trait...
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...crosses and water them correctly so that we could observe the different phenotypes and compare them to Mendel’s proposed ratios. Mendel, who had studied peas, did a similar experiment and came up with specific ratios that a monohybrid and dihybrid cross should show. His findings were that for a monohybrid cross, such as my crosses three and six, the phenotypes would have a ratio of 3:1 (Russell 2003). My results show that cross six fails to reject Mendel’s hypothesis with a ratio of 3 purple to 1 non-purple plant observed. However, cross three did reject Mendel’s hypothesis because epistasis was involved (Strickberger 1985). The results of my last monohybrid cross, cross three, showed a phenotypic ratio of 9 with a yellow tip to 7 all green plants. The dihybrid cross that my group generated showed a 9:3:3:1 ratio of phenotypes, which is the ratio Mendel proposed for such a cross. The phenotypes visible for the dihybrid cross were red stem green leaf, red stem white leaf, no red stem green leaf, and no red stem white leaf. Introduction Genetics, which is the science of heredity, has four major areas. One of these areas is called transmission or Mendelian genetics, which deals with the transmission of genes from generation to generation (Russell 2003). Within this area, there are hereditary traits, which are controlled by genes. As studied by Mendel, genotype and phenotype are both characteristics of an organism. Genotype is the genetic make-up of an organism while phenotype is...
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...Imagine you are a genetic counselor. You counsel couples both before and after pregnancy on fertility, genetic disorders, and pregnancy issues. Several couples you counseled are discussed below. What may they learn by going to you, a genetic counselor? 1. The Millers have one brown-eyed female child and one male blue-eyed child. They are twins. How is this possible? Explain how that is possible by reviewing the phenotype and genotype of each child. There are two different types of twins: monozygotic twins (identical) and dizygotic twins (not identical). In this case, the twins are dizygotic because they do not share the same characteristics or gender, so each twin has his/her own set of genes from the parents. It is likely that one of the parents was heterozygous and the other parent was either homozygous recessive or heterozygous for the gene. Heterozygous means that the parent carries both a dominant and a recessive gene, but only the dominant gene is expressed. The other parent could have been homozygous recessive for the gene. Since brown is the dominant trait, the child who had the brown eyes inherited the dominant trait from one of the parents. It is likely that both of the parents carried the recessive trait for blue eyes, so it is possible for there to be one brown-eyed child and one blue-eyed child. 2. You explain several possible genetic disorders to a couple. Explain how sickle-cell anemia, Down syndrome, and/or hemophilia are genetically transmitted. Sickle...
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...Theodosius Dobzhansky was a scientist that had a large impact on science in the fields of genetics and the Theory of Evolution. Dobzhansky was born on January 25, 1900 in Nemirov, Russia. He moved to the United States of America in 1928 after graduating collage. Theodosius decided he wanted to be a biologist at the age of 12 while he was collecting butterflies because he was fascinated by the way the butterfly worked. Theodosius graduated from the University of Kiev. And moved to the United States to work at Columbia University to be a fellow to geneticist Thomas Hunt Morgan. A geneticist is a biologist who studies genetics. He studied new versions of genes. Theodosius Dobzhansky experimented on fruit flies, in Thomas Morgan’s “Fly Room”, to show the natural populations of the fruit flies exhibited the same kinds of genetic variations that could be produced artificially by mutation in his laboratory. He also found a new species and published his results in Genetics and the Origin of Species. His species was a set of mutations that would replicate and take over the cells around it. The species, in isolation, would spread to the rest of the cells around it and then mutate them so they are a direct copy of itself until all of the cells are the same. Dobzhansky also elaborated on the Theory of Evolution. He initiated a number of investigations into the basis of hybrid sterility. Hybrid sterility is the inability of the offspring of many hybrids, especially among animals, to be fertile...
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...APPLICATION OF STATISTICS IN MEDICAL GENETICS INTRODUCTION "Significance" has a very particular meaning in biology thanks to statistics. How does this term prove an experiment's results are worth special attention? Once one has performed an experiment, how can one tell if the results are significant? For example, say if we are performing a genetic cross in which we know the genotypes of the parents. In this situation, we might hypothesize that the cross will result in a certain ratio of phenotypes in the offspring. But what if our observed results do not exactly match our expectations? How can we tell whether this deviation was due to chance? The key to answering these questions is the use of statistics, which allows us, geneticists, to determine whether our data are consistent with our hypothesis. Statistics and Human Genetics are twin subjects, having grown with the century together, and there are many connections between the two. Some fundamental aspects in particular the concept of Analysis of Variance, first arose in Human Genetics, while statistical and probabilistic methods are now central to many aspects of analysis of questions is human genetics. The most common areas where one can find an extensive applications of statistical methods in human genetics is * Human Genome Project * Linkage Analysis * Sequencing STATISTICAL GENETICS Statistical Genetics involves the identification of genetic variation to help us understand why certain people are...
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...Use of haiku and mind map to reflect on the lifespan development Name: Institution: Introduction This learning journal is going to look at the chronological approach of the lifespan development and the model of hierarchical complexity theory of human development (Michele & Hoffnung, 2013). Topic one: biological foundation and genetics. In this subject, I am going to use the photo as the method of discussion. The choice of photo is because there are several photos I have come across several pictures about the biological foundation and genetics. For instance, the picture below shows the relationship between genetic variation in the biology, the environment and the behavior of an individual. The above talking point gave me the desire to find more about the genes because I realized that I know microscopic about the hereditary genetics. I had petite knowledge about the dominant and the recessive genes in which I did not know the parts they played in a human body. The knowledge that I have about genetics is that it is not always guaranteed for the traits of the parents always pass to the children. For instance, leadership is a character that some parents do have but they happen to have some of the rudest children. Moreover, there is no any relationship between genes and a person’s lifespan. Death is a natural happening that comes an unannounced. The only that that I knew genes do influence are the body complexions like the skin color, height, weight gain and eye color...
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...Chapter 14 Mendel and the Gene Idea Lecture Outline Overview • Every day we observe heritable variations (such as brown, green, or blue eyes) among individuals in a population. • These traits are transmitted from parents to offspring. • One possible explanation for heredity is a “blending” hypothesis. ° This hypothesis proposes that genetic material contributed by each parent mixes in a manner analogous to the way blue and yellow paints blend to make green. ° With blending inheritance, a freely mating population will eventually give rise to a uniform population of individuals. ° Everyday observations and the results of breeding experiments tell us that heritable traits do not blend to become uniform. • An alternative model, “particulate” inheritance, proposes that parents pass on discrete heritable units, genes, that retain their separate identities in offspring. ° Genes can be sorted and passed on, generation after generation, in undiluted form. • Modern genetics began in an abbey garden, where a monk named Gregor Mendel documented a particulate mechanism of inheritance. A. Gregor Mendel’s Discoveries 1. Mendel brought an experimental and quantitative approach to genetics. • Mendel discovered the basic principles of heredity by breeding garden peas in carefully planned experiments. • Mendel grew up on a small farm in what is today the Czech Republic. • In 1843, Mendel entered an Augustinian monastery. • He...
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...1 ABSTRACT The Rapid Cycling Brassica rapa, also known as RCBr, are plants genetically designed to grow at a fast rate. The plant is also well known for the ease of pollination and easy breeding cycle. These traits make RCBr an ideal candidate for testing Gregor Mendel’s theories of inheritance. Brassica rapa acts as a test subject in testing cross-pollination, allowing the understanding to the dominant allele of colored stems. The stems that were visible above the soil ranged from green to purple. The purple coloring was caused by anthocyanin. The anthocyaninless gene (anl), determines whether or not anthocyanin will be expressed. In the homozygous, recessive form (anl/anl), anthocyanin expression is completely suppressed, and the plant stems appear a bright green color. If the genotype is anl/ANL or ANL/ANL, then anthocyanin is expressed at varying levels and the plants are purple. The complete data was used to agree or disagree with Mendel’s theories. 2 INTRODUCTION Needs to have background and explains relevance of understanding genetics using cogent examples. Question, hypothesis and prediction clearly stated. Based on at least three independent sources (see below) with correct citations. Description and explanation of experimental system being used. 3 MATERIALS AND METHODS Conveys experimental procedure in sufficient detail such that experiment could be repeated by a student next semester. Timeline of events is present. Past tense used. Written in narrative/prose form...
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...Gregor Mendel is the scientist who discovered the study of genetics. He started studying the genetic inheritance in pea plants. After that he came up with three laws of the concept of modern genetics which are Mendel’s low of segregation, Mendel’s low of independent assortment, and Mendel’s low of dominance. Mendel’s low of segregation, Mendel stats that every trait has two alleles and every gamete receive just one of this allele. The Law of Independent assortment states that the allele for a separate trait is independently for another trait. Drosophila melanogaster, the famous fruit flies, which geneticists have used as a model in their experiments for many years. Due to the size, amount of offspring produced, easy to discover the mutation,...
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