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Hepatocellular Carcinoma Research Paper

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The liver is the largest internal organ, representing 2%-3% of the total body weight. It is found in the right upper quadrant of the abdomen, and surrounds the inferior vena cava, and attaches to the diaphragm and parietal peritoneum by ligaments. The vascular supply of the liver includes the hepatic artery and portal vein. The liver has many functions which are important and vital for life. These functions include detoxification, excretion of metabolic wastes and hormones, and the production of most proteins. Because of this, dysfunction of the liver causes lethal complications, which is why in hepatocellular carcinoma, in which the liver slowly loses its function, patients are incapable of sustaining life.
Hepatocellular carcinoma (HCC) is a …show more content…
This is a problem because most people who get liver cancer get it in the setting of the chronic liver disease, cirrhosis. Cirrhosis is the irreversible fibrosis or scarring of the liver. There is a growing problem with cirrhosis, which has become a significant problem, given the obesity epidemic occurring in the United States. This is because obesity has been linked with a growing population of patients with non-alcoholic fatty liver disease (NAFLD), which can progress to fibrosis, cirrhosis, and can then lead to hepatocellular carcinoma. These patients are expected to cause an epidemic in hepatocellular carcinoma in the United States and other developed countries. There are certain anatomic patterns that should be considered when dealing with liver injury. The average age at diagnosis is 65 years with an increasing incidence with age; however, there has been an increasing number of young patients with liver cancer due to alcoholic liver disease, as well as hepatitis C. The increase of both alcoholic liver disease and hepatitis C increases the risk of cirrhosis and subsequent hepatocellular carcinoma. Another risk factor is being male, with

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