...of co-infection of HIV/AIDS and Tuberculosis in Urbanized regions within Sub-Saharan Africa Sistla Sumanth Introduction: Airborne communication of mycobacterium tuberculosis is responsible for the evolution of primary tuberculosis (TB) in immunostable and immunocomprimsed patients (Aaron, et al. 2004). In 1993, the center for disease control classification identified that TB was the defining illness in HIV infected patients, as it is typically the first symptom bearing illness to afflict the patient (Aaron, et al. 2004). TB cases have dramatically increased in the global setting in recent, particularly in Sub-Saharan Africa, illustrating the sensitivity of HIV infected patients to this co-infection. TB results from a pathogenic infection caused primarily by M. tuberculosis, and seldom Mycobacterium bovis; the infiltration of the bacterium into the respiratory tract leads to the infection of the macrophages and cytotoxic cells debilitating intracellular growth (Aaron, et al. 2004). The risk of HIV infected patients to succumb due to the co-infection of tuberculosis and HIV is twice that of patients only infected with HIV (Aaron, et al. 2004). A 1997 estimate suggests that atleast 10.7million people were co-infected with HIV and M. tuberculosis; more than 30% of TB cases in Africa are also infected with HIV (Aaron, et al. 2004) showing the susceptibility of co-infection in immunocompromised patients. Those living in Sub-Saharan Africa are in greater risk...
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...in the sub-Saharan Africa region. Famine, on the other hand, is not as widely talked about, around the world, but leads to the same result, numerous amounts of deaths. Hundreds of thousands to millions of people in sub-Saharan Africa have died as a result of this crisis in different nations, such as Sudan, Ethiopia, (fill in different countries). However, famine is not something that happens overnight, and many factors lead to this major crisis. There are many major factors that build up to the final occurrence of a famine in sub-Saharan Africa. The major causes of famine are droughts, war, economic issues, and food distribution. One of the five causes may lead to a major famine, however, when two or more of the causes “work together” to produce a famine, the situation may become hectic. For example, if a war happens to erupt during a drought, it becomes harder for a nation to prevent an all-out famine crisis rather than if their was just a drought. It has become apparent that international and national intervention is needed to help prevent future famines from taking place. Organizations such as the United Nations (UN), Food Association Organization (FAO), United States Aid (USAID), World Food Production (WFP), Red Cross, etcetera. have been trying to be successful in preventing famines, but cannot succeed without national intervention from governments. Therefore, the many committees must work together in a major attempt to avoid such occurrences and get sub-Saharan...
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...[pic] HIV/AIDS INFECTION: A THREATHENING VIRAL DISEASE By Raymond G. Cervantes John Rey Hesita March, 2010 Mr. Armando Torrente Professor OUTLINE I. Introduction-------------------------------------------------------------------------------------------1 A. Background of the Research-------------------------------------------------------------------------1 B. Statement of the Problem------------------------------------------------------------------ ----------3 C. Importance of the Paper------------------------------------------------------------------------------3 D. Definition of Terms ----------------------------------------------------------------------------------3 II. Body----------------------------------------------------------------------------------------------------5 A.Modes of Transmission of HIV/Aids (Direct Factors) ----------------------------------------5 1.Sexual Transmission-----------------------------------------------------------------------------------5 2,Mother to Child Transmission------------------------------------------------------------------------5 3.Transmission via Fomites-----------------------------------------------------------------------------5 4. Needles--------------------------------------------------------------------------------------------------5 5. Blood Traces--------------------------------------------------------------------------------------------6 6. Routine Medical...
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...affected thirty-six point nine million people world wide, with two point six million being children (global stat1). Even though HIV/aids affects people world wide the vast majority of people living with HIV are in low income countries, particularly in Sub-Saharan Africa. That is why whenever the word aids/HIV comes up in a conversation,...
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...1.1 INTRODUCTION HIV and AIDS pandemic in the African continent has had a short but devastating history. Sub-Saharan Africa is more profoundly affected by HIV as compared to any other part of the world. Approximately 23 million people are said to be living with the deadly virus in the region which translates to about two thirds of the universal total. In 2010 alone, around 2 million people contracted the disease while 1.2 million died in sub-Saharan Africa. Since the onset of the pandemic, over 15 million children have lost one or both of the parents to HIV and AIDS. The social- economic effects of AIDS pandemic have not only been experienced in the health sector but also in agriculture, transport, human resource, education and the economy as at large (UNAIDS 2010). HIV and AIDS is therefore a major burden and challenge to the social, health and economic development of the African continent. There can be no significant growth in the region as long as the issue of AIDS is not addressed urgently. The impact of HIV and AIDS in the African continent and the world at large cannot be down played. This means that immediate measures should be taken by the general public and governments in order to curb the ever increasing effects of HIV pandemic to the African continent. Due to the economic standing of the African continent coupled with socio-cultural practices, HIV continues to spread at an alarming rate. Any further delays to address this issue will turn out to be detrimental...
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...Research Proposal on HIV Posted at: February 9, 2010 under: Sample Research Proposals by admin @ 7:04 am Problem Twenty years ago, the subject of HIV (human immunodeficiency virus), which has been found to be the cause of AIDS (acquired immunodeficiency syndrome), would not have been the topic of a major and serious worldwide catastrophe. Twenty years ago, people were not phased by the effects that would be caused by this ever so populating disease, and no one would have ever realized that this disease would not be curable or helped without expensive medicine. Like a simple exponential growth equation, the AIDS virus has increased victim numbers by about forty million all over the world. AIDS has also shown that it is not discriminating; it has infected all races and all heritages. The AIDS crisis extends far beyond its death toll, because more than seventy percent of the thirty-six million people with HIV/AIDS live in sub-Saharan Africa. Last year alone, the disease killed 1.5 million people in Africa. One third of these victims are between the ages of ten and twenty-four. The disease has been described as a development crisis; it is profoundly disrupting the economic and social bases of families and entire nations at a rate of infection at 16,000 per day. Without immediate action, AIDS will surpass the effect of the Black Plague that killed forty million people in the late fourteenth century. It is estimated that only ten percent of the death that this disease...
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...percentage of the land? 5. What does GPS stand for? How is it used here? 6. What are the major issue(s) that land reform face? 7. What two items are compared in the process of “ground truthing”? 8. What disease is most widespread in sub-Saharan Africa? 9. Approximately how many of the worlds cases of AIDS / HIV occur in sub-Saharan Africa? 10. How has the United Nations assisted in sub-Saharan Africa’s AIDS / HIV crisis? 11. What do we call the spread of a phenomenon over space and time? What is the difference between its Hierarchical and Contagious forms? 12. In the mid to late 1980’s HIV in Kenya was confined to which region(s)? Why do you think this was the case? 13. Describe how AIDS / HIV diffused across Kenya from the mid 1980’s to the mid 1990’s. 14. Which area had the most successful anti- AIDS campaign?? Answer the following Questions on a separate sheet of paper. 1. Do you think the land reform programs in South Africa have been successful? Support your answer with examples. 2. The world is (or should be) aware that sub-Saharan Africa’s has a devastatingly high rate of AIDS / HIV but may not be as aware as to why the rates are so high. Discuss the possible reasons as to why the rates are so...
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...The impact of HIV & AIDS in Africa Two-thirds of all people infected with HIV live in sub-Saharan Africa, although this region contains little more than 10% of the world’s population.1 AIDS has caused immense human suffering in the continent. The most obvious effect of this crisis has been illness and death, but the impact of the epidemic has certainly not been confined to the health sector; households, schools, workplaces and economies have also been badly affected. During 2008 alone, an estimated 1.4 million adults and children died as a result of AIDS in sub-Saharan Africa.2 Since the beginning of the epidemic more than 15 million Africans have died from AIDS.3 Although access to antiretroviral treatment is starting to lessen the toll of AIDS, fewer than half of Africans who need treatment are receiving it.4 The impact of AIDS will remain severe for many years to come. The impact on the health sector In all heavily affected countries the AIDS epidemic is adding additional pressure on the health sector. As the epidemic matures, the demand for care for those living with HIV rises, as does the toll of AIDS on health workers. In sub-Saharan Africa, the direct medical costs of AIDS (excluding antiretroviral therapy) have been estimated at about US$30 per year for every person infected, at a time when overall public health spending is less than US$10 per year for most African countries.5 The effect on hospitals [pic] Nurses working on the HIV ward at Kisiizi Hospital in Uganda ...
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...Malaria is the leading death, illness, and poor growth in developing countries of Sub-Saharan Africa. Malaria is a parasitic disease spreading through mosquito bites that involve high fevers, flu-like symptoms, and death. The World Health Organization (2012) reported over a million deaths are attributable to Malaria and 90% of all deaths caused by the disease occur in sub-Sahara Africa. According to the 2012 report from the World Health Organization (WHO), an estimation of 600,000 deaths occurs every year in Sub Sahara Africa, in which a child dies each minute. These young victims are mostly children under five years of age. Many techniques have been put into place to help eradicate the disease, but a lack of well-targeted education systems, which is one of the most effective tools, remains a serious challenge in Sub-Saharan Africa Despite the availability of such many strategies, there is a need to propose a new study that will outline how we can make significant difference in the education systems by the way we use Mobile Technology. Summary To ensure the management, and control of the disease, the data collection will help determine if the disease has a direct correlation to the level of social education, to the lack of adequate resources, good governance in the political arena, lack of Health care services or the financial burden from the affected families? In combination with other research, the recommendation provided by this study will help sustain economic and social...
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...Demographic transformation: the dilemma of sub-Saharan Africa Demographic transformation or transition is referred to as the process by which a country moves from high birth and high death rates to low birth and low death rates with population growth in the interim. The demographic transition model is comprised of 5 stages. The Sub- Saharan African region is believed to be still in stage 1, which refers to having high death rates and high fertility rates (birth rates) although the condition is far better than it was just a few years back. The demographic transition started in European populations living in Europe and elsewhere around 1880 and at present, almost all developing countries have entered the demographic transformation, i.e. mortality rates are declining and fertility rates follow. It was believed that countries in Sub-Saharan Africa will also follow the same pattern. But the demographic transformation has taken the speed of a slug in this part of the world. Sub-Saharan Africa mostly consists of countries regarded as underdeveloped or developing and is part of the so-called Third World. Third World countries share many characteristics but at the continental level they are not the same. For instance, sub-Saharan Africa is sparsely populated, in contrast to South and East Asia, and it is much less urbanized than Latin America. It stands out amidst the other major regions of the Third World for having the slowest rate of economic growth in recent years: an average annual...
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...Western Drug Companies and the AIDS Epidemic in South Africa In December 1997, the government of South Africa passed a law that authorized two controversial practices. One, called parallel importing, allowed importers in South Africa to purchase drugs from the cheapest source available, regardless of whether the patent holders had given their approval or not. Thus South Africa asserted its right to import “generic versions” of drugs that are still patent protected. The government did this because it claimed to be unable to afford the high cost of medicines that were patent protected. The other practice, called compulsory licensing, permitted the South African government to license local companies to produce cheaper versions of drugs whose patents are held by foreign companies, irrespective of whether the patent holder agreed. The law seemed to be in violation of international agreements to protect property rights, including a World Trade Organization agreement on patents to which South Africa is a signatory. South Africa, however, insisted that the law was necessary given its own health crisis and the high cost of patented medicines. By 1997, South Africa was wrestling with an AIDS crisis of enormous proportions. It was estimated that over 3 million of the country's 45 million people were infected with the virus at the time, more than in any other country. However, although the AIDS epidemic in South Africa was seen as primary reason for the new law, the law itself was applied...
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...Western Drug Companies and the AIDS Epidemic in South Africa In December 1997, the government of South Africa passed a law that authorized two controversial practices. One, called parallel importing, allowed importers in South Africa to purchase drugs from the cheapest source available, regardless of whether the patent holders had given their approval or not. Thus South Africa asserted its right to import “generic versions” of drugs that are still patent protected. The government did this because it claimed to be unable to afford the high cost of medicines that were patent protected. The other practice, called compulsory licensing, permitted the South African government to license local companies to produce cheaper versions of drugs whose patents are held by foreign companies, irrespective of whether the patent holder agreed. The law seemed to be in violation of international agreements to protect property rights, including a World Trade Organization agreement on patents to which South Africa is a signatory. South Africa, however, insisted that the law was necessary given its own health crisis and the high cost of patented medicines. By 1997, South Africa was wrestling with an AIDS crisis of enormous proportions. It was estimated that over 3 million of the country's 45 million people were infected with the virus at the time, more than in any other country. However, although the AIDS epidemic in South Africa was seen as primary reason for the new law, the law itself was applied...
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...The Direct and Indirect Effects of HIV/AIDS on Children and Youth in Africa Rojish Thomas English 202A June 21, 2012 The Direct and Indirect Effects of HIV/AIDS on Children and Youth in Africa HIV and AIDS are two of the most prevalent illnesses around the world today. HIV, or the human immunodeficiency virus, leads to AIDS, or the acquired immune deficiency syndrome. The disease damages a person’s body by destroying the blood cells that work to fight diseases; or in other words, by destroying a person’s immune system (“Basic Information about HIV and AIDS”, 2012). There are many adults all around the world who have acquired and have passed away from this disease. Africa is well known to have the highest rates of HIV/AIDS than any other continent in the whole world. However, not many people realize how much the disease has affected children and youth along with adults. Children and youth in Africa suffer from HIV/AIDS in both direct and indirect manners. The direct effect of HIV/AIDS on children in Africa is the children themselves suffering from the disease. Children and youth indirectly suffer from the diseases as a result of their parents or siblings being diagnosed with AIDS. They then must take care of their family members although the children may be very young; they are even poorer than they were before with their parents unable to work because of the disease; and in many cases they are orphaned and left to fend for themselves and their siblings to find food,...
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...GlaxoSmithKline and AIDS Drugs for Africa GlaxoSmithKline Pharmaceuticals Ltd Trimester 1 Project – Division D Prepared By (Group 4) :Nakul Agarwal Sanket Guhagarkar Tanvi Gupta Piyush Jain Saurabh Jain (D004) (D020) (D026) (D029) (D030) Table of Contents Company Overview....................................................................................................................... 1 HIV / AIDS in Africa ................................................................................................................... 1 Core interest of GSK in Africa .................................................................................................... 1 Criticism of GSK ......................................................................................................................... 1 Access to Medicine (ATM) Outlook ............................................................................................ 2 Governance .................................................................................................................................... 2 Management Structures....................................................................................................... 3 Performance Management & Incentives ............................................................................. 3 Stakeholder Engagement..................................................................................................... 4 Innovation in General Access to Medicine...
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...economic, and cultural impacts within human societies. The differences and similarities of these pandemics can help us understand pandemics better and also can help us to prepare for future pandemics. First we must look at the bubonic plague, how it spread and how it impacted the world socially, economically, and culturally. It was first recorded in Europe by a Sicilian chronicler by the name of Michele da Piazza in October of 1347, who recorded the port of Messina having twelve galleys full of sailors carrying the disease down to the marrow of their bones.1 Black Death began to really take its toll in 1348, spreading through Italy, France, Spain, Switzerland, Austria, England, Denmark, to the Balkans, Palestine, Syria, and the coast of North Africa by the spring and summer of that year. By 1350 it had reached German and Eastern Europe and finally in 1352 reached Russia. Spreading from port to port, through trade and travel, from what appears to be person to person.2 Unlike the modern day agent of Black Death, that is only spread as fast as...
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