Human Genome Project and Clinical Research
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Having whole structure of the human genome is like having a complete manual needed to make the human body. The challenge to scientist now will be to read the contents of the manual’s content, understand how the parts correlate, discover the genetic basis for health and the pathology of diseases that plague human beings. Genome based research, will eventually enable researchers to develop efficient diagnostic tools, to understand the health needs of individuals, based on their genetic makeup and help in designing effective treatments for diseases. Personalized analysis based on individual genome, may lead to a powerful form of preventative medicine that will be able to learn about risks of future diseases, based on the DNA analysis. Health care professionals like the physicians, doctors, nurses and genetic counselors, will be able to work with patients and focus their energies on things that are likely to maintain health for a person (Lander, 2011, p.190). That may as well mean lifestyle changes or diet it might also mean medical monitoring. Through understanding of the molecular level of how diseases like schizophrenia, diabetics and heart diseases come about, new generations of interventions that are more efficient and precise that today’s interventions may be formulated. Cancer is among the most devastating ailments in the society today. It is a random killer and has given a face in the millions of its victim’s each year. People nowadays fear that they already know the prognosis every time they experience abnormal prognosis for the duration of time (Hudson, Anderson, Aretz, Barker, Bell, Bernabé, et al, 2010, p.995). If I received a generic test that indicates 85% as the probability of developing any cancer, I would strive for optimal health, increase my cancer protective factor and reduce its risk factors. Even though making healthy lifestyle choices does not guarantee a person will be remain cancer free, studies have shown that people who makes healthy choices lowers their chances of developing cancers. I would adopt the many recommendations that have been universally endorsed by the health care providers, as known to improve the body’s ability to fend off cancer. To further step up my monitoring I would initiate timely open dialogues with my doctor and arrange for routine screening so that, in case the tests suggest probable cancer, the results can quickly be explored further. The striking features of scientific research in biomedicine today is the ubiquity of genetic strategies and genomic tools. The genetic research trials are done with human subjects in a way that was largely unanticipated by the research regulations. As different research teams goes for gene hunting, an increasing number of review boards and investigators are finding that both the federal regulations and the research ethics works are fundamentally silent on the major concerns that genetic families and populations studies raise (Gallin, & Ognibene, 2012). The normal standards appear to assume that partners of biomedical exploration subjects ordinarily consist of strangers, rather than people who live together as kinfolk’s members or group members. At the same time, a baffling variety of domestic practices have progressed the genetic research community to manage these challenges. While their advocates often defend local approaches to problems passionately, they all have their criticizers. As the gene hunting procedures increase within biomedicine, the need for broader discussion and holistic training with respect to these issues is growing. Some do not identify all the possible gene mutations that can cause a condition and others have limited predictive value.

References
Gallin, J. I., & Ognibene, F. P. (Eds.). (2012). Principles and practice of clinical research. Academic Press.
Hudson, T. J., Anderson, W., Aretz, A., Barker, A. D., Bell, C., Bernabé, R. R., ... & Lichter, P. (2010). International network of cancer genome projects. Nature, 464(7291), 993-998.
Lander, E. S. (2011). Initial impact of the sequencing of the human genome. Nature, 470(7333), 187-197.