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Joints

In: Other Topics

Submitted By briaunal
Words 1208
Pages 5
Joints are a location at which bones connect. Allowing movements and providing mechanical support. Joints are classified structurally and mechanically. A disease of the joint in which inflammation occur is arthritis. Inflammation of one or more joints is called Arthritis. There are several different forms of arthritis. This paper will discuss Gouty arthritis.
The word Gout comes from Latin gutta and old French gote meaning “a drop”(Pillinger, Rosenthal & Abeles,2007).
Several hundred years ago gout was thought to be carried by drops of viscous liquid that seeped from blood into the joints.
Gout was once described as the disease of kings, because it was the wealthy who could afford the rich food, which seem to precipitate gouty attacks. Gout has developed a much greater incidence and prevalence. The incidents of gout are on the rise predominantly in the elderly. In those older than sixty-five years, the prevalence has just been increased by sixty percent between nineteen ninety and nineteen ninety-nine. In those seventy-four years and older, the prevalence doubled due to the comorbid conditions, obesity, hypertension, alcohol use, and metabolic syndrome (Doheny, 2009; So, 2008). Men are a higher risk in developing gout than women. Estrogen seems to have a uricosuric effect in women, which helps reduce their premenopausal risk. After menopause women risk increase for gout due to a decrease in estrogen and the loss of protective effect (Weaver, 2008). Most cases of gout are inherited.
Gout by definition is a decrease of purine metabolism, a sudden rush of increased uric acid in the blood. Uric acid is the end product of purines catabolism. Purines are the building blocks of several biologic constituents including nucleic acids, neurotransmitters, coenzymes, and cell messengers (Cannella & Mikuls, 2005).
When human bodies break down chemicals called purines...

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