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Medicines

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Drugs | Classification of drugs | Mechanism of action | Indication | contraindication | Intervention | MechlorentamineHydrochloride (nitrogen mustard)Mustargen | >Alkylating drugs | Alters DNA molecule, cross-linking DNA stronds. | To treat bronchiogenic carcinoma, CML, hodgkins disease, lymphosarcoma, and mycosis fungiodesTo treat malignant pericardial, peritoneal, or pleural effusions | * Infection * Recent surgery * Impaired renal failure * Recent radio therapy * Pregnancy * Bone marrow depression | * Administer vesicants only if you are highly knowledgeable with the drug. * Prepare in accordance with the manufacturer instruction * Avoid using the vein * Begin at the most distal site * D/C if suspected of extravasation |

Drugs | Classification of drugs | Mechanism of action | Indication | Contraindication | Intervention | Dactinomycin(actinomycin-D)Cosmegen | >Antibiotic antineoplastics | Interfere with DNA synthesis by binding to DNA prevent RNA synthesis. | To treat erwing’s sarcoma, gestational trophoblastic or whilm’s tumors, rhabdomyosarcoma, sarcoma botryoides, and testicular cancer tumors.To treat erwing’s sarcoma and sarcoma botryoides | * Infection * Recent surgery * Impaired renal failure * Recent radio therapy * Pregnancy * Bone marrow depression | * Administer vesicants only if you are highly knowledgeable with the drug. * Prepare in accordance with the manufacturer instruction * Avoid using the vein * Begin at the most distal site * D/C if suspected of extravasation |

Drugs | Classification of drugs | Mechanism of action | Indication | Contraindication | Intervention | Doxorubicin hydrochlorideAdriamycin PFS,Adriamycin RDF, Rubex | >Antibiotic antineoplastics | Interfere with DNA synthesis by binding to DNA prevent RNA synthesis | To treat acute lymphocytic leukemia;

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