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Mitochondrial Myopathy

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Mitochondrial myopathies are a group of diseases and not just one particular disease. However, all these diseases affect only one thing in our body. This one thing is the mitochondria. Those who have studied human genetics or similar sciences, know that mitochondria are present in all our nerve cells and deal with the functions our muscles. These mitochondria are what provide energy to our cells which in turn help in movement of muscles et al. If these mitochondrial problems affect only the muscles, the disease is known as a mitochondrial myopathy, where myo stands for muscle and pathos stands for disease. On the other hand, if they affect both, the muscle and the brain, it is called as a mitochondrial encephalomyopathy, where encephalo stands for brain. Group of Mitochondrial Myopathy Diseases include: Kearns-Sayre syndrome (KSS), Mitochondrial DNA Depletion Syndrome (MDS), Mitochondrial Encephalomyopathy; Lactic Acidosis and Stroke Like Episodes (MELAS), Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE), Myoclonus Epilepsy with Ragged Red Fibers (MERRF), Progressive External Ophthalmoplegia (PEO), Neuropathy, Ataxia and Retinitis Pigmentosa (NARP), Leigh Syndrome, and Pearson Syndrome. Now, the question what causes mitochondrial myopathy? All of know that our body is made with the help of genes. The particular type of genes that affect mitochondrial diseases are those that make proteins, which in turn, work inside the mitochondria. Mitochondria refers to a lot of energy factories, its singular is known as mitochondrion. Inside each of these mitochondrions, fuel molecules obtained from food are used to manufacture or produce ATP, the energy molecule. This process of manufacturing needs oxygen and there aren't many proper ways of producing the ATP outside the mitochondrion. Now what happens is this. Proteins get the fuel molecules, wiz. the fats and

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