Evidence suggests that the investigation of crimes occurred as far back as prehistoric times when early man took fingerprints by pressing hands and fingers into clay or rock. In Nova Scotia, archaeologists uncovered an ancient drawing of the detailed ridge patterns of a hand. Additionally, the ancient Babylonians also made use of fingerprinting on clay tablets for business transactions and as a means to preserve identification for other official needs. Forensic science continued to evolve, and in 700 B.C., the Chinese began to record thumb prints on clay sculpture and documents despite having no formal classification system was in place. In 250 B.C., an ancient Greek physician, Erasistratus, created the first lie detector test when he noted that his patients' pulse rate appeared to increase when they lied. In 44 B.C., a Roman doctor examined Julius Caesar's body and discovered that of his 23 stab wounds, only one was fatal. The 1100 A.D., crime scene investigation had improved to such a degree that Roman attorney Quintilian proved that blood-covered palm prints were left at a crime scene to frame a blind man for the murder of his mother. Nearly 150 years later, in 1248 AD, the first documentation of medical knowledge aimed at solving crimes was recorded in the book "Hsi Duan Yu" (the Washing Away of Wrong). It detailed the process of distinguishing drowning from strangulation. Over the next 500 years, advancements in crime scene investigation focused on the many aspects of fingerprint detail and chemical elements like poisons. In 1813, Mathieu Bonaventure Orfila, who is considered the father of modern toxicology, published "Traite des Poisons," and in the mid-1800s, investigators at Scotland Yard began to conduct bullet comparisons. Following these advancements, investigators developed successful tissue tests that identified arsenic as a means of murder.