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Pathophysiology of Diabetes

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Student number 213059356

HND 701 pathophysiology of Diabetes
Assignment 1
Word count 2130
Student name Trevor Clemens
Student number 213059356

Page 1 of 17

Student number 213059356

Many aspects must be taken into consideration in attaining knowledge and understanding of diabetes, it is not just a metabolic process. There are multiple risk factors that precipitate the metabolic process leading to a diagnosis. The following analyses relevant data in relation to pathophysiology, presenting signs, symptoms and underpinning principles of Type One Diabetes Mellitus (T1DM) and Type Two Diabetes Mellitus (T2DM), their prevalence and incidence, metabolic abnormalities and associated risk factors are also examined.
Diagnostic criteria is also examined along with advantages and disadvantages of differing testing screen methods and results.

The Australian Bureau of Statistics (ABS), Australian Health Survey 2012, reported that in 2011 – 12 the prevalence of all reported diabetes was at 4.0%
(875,400 people) and had remained the same as the 2007/’08 period. Of these people 12.4% had T1DM, 85.3% had T2DM while the remaining 2.3% had diabetes of another kind. Tanamas S, et al. (2013) stated that the prevalence of type two diabetes in peoples over the age of 25 years in Australia is 7.4% and that a further 7.4% remain undiagnosed. The dominance of western lifestyles and diets has contributed to a dramatic rise in obesity within the population. It is contended that obesity is preventable and reversible. Type Two Diabetes Mellitus
(T2DM) develops within a significant percentage of the obese populous (Connor
T et al 2015, Kasuga M 2006, O’Rahilly S 2009, Prentki M, and Nolan C 2006,
Rouman C, Blaak E and Corpeleijin E, 2009, Tanamas S, et al 2013).

Apart from obesity and inactivity people diagnosed with T2DM often have other contributing risk...

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