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Pathophysiology Of Disease Essay

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Introduction and pathophysiology of the disease:
Malaria is one of the most common dangerous and infectious diseases in all the world specially in south Asia and Africa. In 109 countries, there are about billions of people at risk from infection of malaria. Each year there are about 200 to 250 million cases of malaria disease and so leading to death many of them and most of them are children and their age is under five years. The organism that causes all this dangerous is a microscopic parasite (5 species of it) of genus plasmodium and their names are Plasmodium falciparum, Plasmodium ovale, Plasmodium knowlesi, Plasmodium malariae and Plasmodium vivax. Plasmodium falciparum is the most predominates in Africa and the most dangerous type that
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8- Headache.
9- Bloody stools. 10- Coma.
11- Fatigue. 12- Convulsions.
Methods of transmission/Infection? "causes"
The most common mode of transmission of malaria is by mosquito bites.
A) Mosquito transmission cycle:
1- Uninfected mosquito: a mosquito is not infected but it become infected by feeding on a person who has malaria.
2- Transmission parasite: the second person this mosquito bites, the malaria parasites can be transmitted to him.
3- In the liver: the parasites travel through blood and live in the liver where some types of malaria can be dormant for a long time up to year.
4- In the bloodstream: when the parasites become mature, they leave the liver and begin to infect the red blood cells.
5- On the next person: if the uninfected mosquito bites the person at this cycle, it becomes infected by his malaria parasites and then can spread them to the next person by bites.
B) Other modes of transmission:
People can infected by malaria through the exposure to infected blood as:
1- In blood transfusion.
2- From the pregnant woman to her fetus.
3- By sharing needles or syringes that are used t inject

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