Premium Essay

Peutz Toughers Research Paper

Submitted By
Words 242
Pages 1
Peutz-Jeghers is a rare autosomal dominant disease which greatly shortens life span and results in a a life of invasive surgeries for temporary symptom relief. It is associated with specific characteristics such as polyp formation and skin pigmentation but also greatly increases the risk of tumorigenesis. Specifically, it increases the risk of benign tumours of the ovaries and testes, as well as, increased risk of stomach, esophageal, breast, colon, pancreatic, cervical, and ovarian cancers. This risk is associated with a mutation in STK11 where only half of the people who are diagnosed have previous family history. According to Johns Hopkins University, almost all people with PJS will be diagnosed with one of the associated cancers stated

Similar Documents