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Prevalence of Depression

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Blood Lab First Week
This is a self propelled powerpoint study atlas of blood cells encountered in examination of the peripheral blood smear. It is a requirement of this course that you begin review of these slides with the first day of class in order to familiarize yourself with terms used in describing peripheral blood morphology. Laboratory final exam questions are derived directly from these slides. The content of these slides may duplicate slides (1-37) listed on the Hematopathology Website. You must familiarize yourself with both sets of slides in order to have the best learning opportunity.

Before Beginning This Slide Review
• Please read the Laboratory information PDF under Laboratory Resources file to learn about
– Preparation of a blood smear – How to select an area of the blood smear for review of morphology and how to perform a white blood cell differential – Platelet estimation – RBC morphology descriptors
• • • • Anisocytosis Poikilocytosis Hypochromia Polychromatophilia

Normal blood smear. Red blood cells display normal orange pink cytoplasm with central pallor 1/3-1/2 the diameter of the red cell. There is mild variation in size (anisocytosis) but no real variation in shape (poikilocytosis). To the left is a lymphocyte. To the right is a typical neutrophil with the usual 3 segmentations of Med. Utah pathology the nucleus.

Normal blood: thin area

Ref 2

Normal peripheral blood smear. This field is good for exam of cell morphology, although there are a few minor areas of overlap of red cells. Note that most cells are well dispersed and the normal red blood cell central pallor is noted throughout the smear.

Thick area of smear: Red cells are artifactually stacked on one another and do not uniformly show normal central pallor. White blood cells appear rolled up and nucleus can not always be distinguished from cytoplasm. This is

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