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Progress

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Inclusion criteria for the cases will be: women over the age of 50 that have had a recent diagnosis of colon cancer. That means they have had a diagnosis of colon cancer confirmed by a pathologist within the last 30 days of study.Recruitment of cases will come from the Indiana university hospital based off of referrals from physicians within our research group. Cases could also be self-referred if they have seen ads or brochures in the hospitals. The rationale for deriving cases this way is to ensure that their responses to the ffq best reflect their status before they were diagnosed.In regards to the exclusion criteria, anyone with a previous diagnosis of ulcerative colitis, Crohn’s disease, bowel disease, or any other form of cancer will be excluded. Obese individuals, anyone with a BMI of 30 or more, anyone with a history of smoking, and current smokers will also be excluded. The rationale behind that is that those factors could play a crucial role increasing their risk for colon cancer.The controls will be strictly self-referred. We will have fliers and brochures throughout common areas in the hospitals for ppl to see. We will also accept controls from Inresearch.org which has an online registry of healthy volunteers. The same exclusion criteria would apply for controls. | Our plan is to implement a case-control design for our study. We expect the study to take about an hour, before which informed consent will be authorized by all the subjects involved. Upon giving consent, they will take a food frequency questionnaire to give us an estimate of their current portion sizes and to measure their vitamin D and calcium intake. If the subjects have had their vitamin D levels measured within 60 days of the study, we will take that information directly from their medical records; however, if that is not the case, blood will be drawn from the subjects following their completion of the questionnaire. | The study is projected to take a total of three years to complete.In the initial four months of our research, the study will be setup, personnel will be hired, and necessary paperwork will be filed. (institutional review board)We plan to spend the next couple years or so enrolling cases and controls. In order to stay on schedule, our goal is to enroll at least four cases and four controls per month. That way by the 25th month, we should have 100 cases and 100 controls as planned.Upon completion of the study, we plan to spend the final three months analyzing our results and publishing a final draft of our research. |

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