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Bovine Spongiform Encephalopathy:
A look at the molecular level
COMPETENCY 208.5.2: AMINO ACIDS AND PEPTIDE BONDS, PROTEIN STRUCTURE
BY: MELANIE MANGER

Bovine Spongiform Encephalopathy
 

Commonly know as Mad Cow Disease Although the United States has strict standards when it comes to food, BSE is absolutely an international issue



A cow will ingest a food (usually a protein) that is contaminated, we as humans then in turn become infected when we eat food products made up from that particular cow
Prions are an infectious agent that cause a protein in the body to fold abnormally form. Those proteins then replicate within the body and lead to brain degeneration and ultimately will cause the death of the infected individual



BSE: The Molecular Level
  

DNA makes RNA  RNA makes amino acids  chains of amino acids make proteins Amino acids have an amine group on one end and a carboxyl group on the other, with a Hydrogen and an R group (1 of 20 amino acids) attached to the Carbon. The amine (or amino) end of the peptide chain is known as the N-terminal, and the end with the carboxyl group is the C-terminal.

Amino Acids (March 31, 2013). Retrieved July 16, 2014 from http://biochemanics.wordpress.com/2013/03/31/amino-acids/ BSE: The Molecular Level


Peptide bonds are what link 2 amino acids together at the carboxyl group of one and the amine group of another



Peptide bonds are created through dehydration synthesis and broken down through a process known as hydrolysis. In dehydration a water molecule is removed to form the bond and in hydrolysis a water molecule is added to break up the bod.

Peptide bonds (December 13, 2013). Retrieved July 16, 2014 from http://commons.wikimedia.org/wiki/File:224_Peptide_Bond-01.jpg Leucine


The human body can synthesize 10 of the 20 amino acids. Those 10 amino acids that the body is unable to synthesize are know...

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