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Psychiatry

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Submitted By savana786
Words 7400
Pages 30
716

Index

major depressive disorder, brain imaging studies, 70–71 malignant catatonia, 333 malingering, 530–531
‘manic depressive insanity’, 45 manic states, 250, 253 abnormal beliefs and perceptions, 254 amphetamines and, 266 course and outcome, 274 delusional, 16 in HIV patients, 345 in ICD-10, 42 in old age aetiology, 369 clinical features, 370 treatment, 370 in old age, 369–370 mixed state with depression, 255 sensations in, 6 stroke and, 344 stupor in, 31 manic states, 15–17
Marchiafava-Bignami syndrome, 206, 338
Marijuana Anonymous, 239 marital status, and suicide, 454 masculinity drunkenness and, 428 sense of, 395
Massachusetts Male Aging Study, 402
Massachusetts Women’s Health Study (MWHS), 442 masturbation, 396
McNaughton Rules, 558
McNaughton, Daniel, 558 m-CPP 435
,
MDMA (3, 4-methylenedioxymethamphetamine;
‘ecstasy’), 328 medial temporal lobe volume in Alzheimer’s disease, 359
MRI for detecting, 75 medical conditions anxiety disorders in, 170 depression treatment, 521 detection of psychiatric illness, 483 feigned illness, 530–531 mental disorders due to, 327 anxiety disorders, 333 cannabis and psychosis, 330 catatonia, 332 cognitive disorders, 334 delusions, 329

depression and Parkinson’s disease, 332 general principles, 327 hallucinations, 328 mood disorders, 330 personality disorder, 333 psychotic disorder, 328 stimulant psychosis, 329 mental disorders due to, 326–335 relationship to affective change, 270 suicide risk and, 455 medically unexplained symptoms, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 523 biological mechanisms, 526 epidemiology, 52 biological mechanisms, 526 epidemiology, biological mechanisms, 526 epidemiology, biological mechanisms, 526 epidemiology, biological mechanisms, 526 epidemiology, biological mechanisms, 52 epidemiology, biological mechanisms,

Index

mental capacity of hospital patients, 532
Mental Disability Advocacy Centre, 509 mental disorders alternative world-views, 424 classification, culture and, 421–424 criminal offenders detention in hospital, 556 fitness to plead, 557 psychiatric defences, 558 defining, 45 descriptions, historical background, 45
DSM-IV numeric code, 43 due to general medical condition anxiety disorders, 333 cannabis and psychosis, 330 catatonia, 332 cognitive disorders, 334 delusions, 329 depression and Parkinson’s disease, 332 general principles, 327 hallucinations, 328 mood disorders, 330 personality disorder, 333 psychotic disorder, 328 stimulant psychosis, 329 due to general medical condition, 326–335 epidemiology, cross-cultural research, 425 intellectual disability relationship to, 388 links to violence, 540–550 neurobiology of violence with, 549 poverty and, 431 rights of persons with, 509 secondary, 326, 327 social determinants, 426 conflict and displacement, 428 gender, 427 indigenous communities, 429–431 poverty, 426 suicide reduction, 462 mental health cocaine use and, 233 legislation in UK, 556 maintenance for those with intellectual disability, 388 sexual life impact on, 406
Mental Health Act 1983, 556 mental health professional, attached, 486 mental health services contextual issues in developing, 500–502

ethical base, 509 historical background asylum care, 499 balanced mental health care, 499 historical background, 498–500 mainstream acute in-patient care, 504 clinical services, 503 community mental health teams (CMHTS), 503 interfaces between services, 505 long-term community-based residential care, 505 need for improvements, 503 occupation and day care, 505 mainstream, 502–506 provided by primary care, 500 with specialist backup, 502 resource levels and, 510 specialised/differentiated community mental health teams, 506 out-patient/ambulatory clinics, 506 specialised/differentiated, 506–509 step-wise delivery, 509
UK law timeline, 555 mental life of patients, curiosity about, 4 mental state examination for dementia assessment, 355 in neuropsychiatry, 321 mental state, abnormalities as symptoms, 3 mescaline (phenylalkylamines, ‘STP’), 328 mesolimbic dopamine, 303 meso-limbic system, and motivated behaviors, 405 mesoridazine, and prolonged QTc, 594 messages, in family therapy, 686 meta-analysis, 66 shortcomings, 67 metabolism of drugs, 568 metaphor, 32 in language disorder, 32 metergoline, 435 methadone maintenance treatment (MMT), 240, 243 effectiveness of legally coerced, 241 vs. IPT, 661 methamphetamines, 235 theoretical dose-response curve, 574 methohexital, 605 microinfarcts, 360 micropsia, 6 midazolam, metabolism, 569 mifepristone, for psychotic depression, 612

717

718

Index

migraine, and depression treatment, 521 migration, and schizophrenia, 293
Milan school, 679, 686 mild cognitive impairment (MCI), 335 in dementia, 353 mind, topography of, 637 mind-brain interface, research, 647 mini-mental state examination (MMSE), 75,
358
Minuchin’s Structural Family Therapy, 679 mirtazapine, 625 for depression in Parkinson’s, 332 sexual side effects, 404 mirtazepine, SSRIs with, 631 misidentification syndromes, 26 misinterpretations, 9 mixed models, in gene finding, 88 mixed states, of depression and mania, 255 moclobemide, 627 for panic disorder, 155 sexual side effects, 404 model-free linkage, 89 molecular genetics, 92 for affective disorders, 263 for alcohol dependence association studies, 212 linkage studies, 212 for alcohol dependence, 212–213 for schizophrenia, 297 molecular genetics, 91–92 molindone, 588 monoamine oxidase inhibitors (MAOIs), 626 for bipolar depression, 609 for panic disorder, 155 monoamine oxidase-a (MAO-A) enzyme, PET radiotracer for, 71 mononucleosis, infectious, and mood change, 270 monozygotic twin pairs, 82
Mood and Affect, 11 mood change animal studies on, 261 neurochemistry of, 264 mood disorders in children, 118 in ICD-10, 41 in menopause, 442 treatment, 442 medical condition impacting, 330

mood stabilizers carbamazepine, 599 for alcohol withdrawal management, 220 for mania in elderly, 370 starting doses for elderly, 364 toxicity, 599 lamotrigine, 600 for mania in elderly, 370 overdose, 600 side effects, 600 lithium, 363 for depression in old age, 369 for mania in elderly, 370 for suicide prevention, 463 reduction in renal clearance, 597 toxicity, 597 lithium, 596–598 oxcarbazepine, 599, 607 recommended pretreatment tests, 598 topiramate, 600 for binge eating disorder, 193 valproate, 598, 604 for affective psychosis, 607 for depressive episode in bipolar disorder, 608 for rapid-cycling illness, 610 recommended pretreatment tests, 598 mood stabilizers, 601 mood, sexual interest reduction, 401 moods, in mania, 15
‘moral insanity’, 45 morbid jealousy, in schizophrenia, 291 morbid risk, 82 morbidity force of disease, in population, 53 motivated behaviors, meso-limbic system and, 405 motor vehicle accidents, cannabinoids and, 231 mouse genomic sequence, 576 movements repetitive stereotyped, 30 slowness, in depression, 251
MRC-ALPHA study, 367 multiple insanity, 27 multiple sclerosis and anxiety, 333 and delusions, 329 and dementia, 335
Munchausen’s syndrome, 531 muscle disease, in alcohol abusers, 208 mutism, 31 selective, 112

Index

myocardial infarction, ECT after, 628 myocarditis, from antipsychotics, 595 myxoedema, and depression, 266 naloxone, 238 naltrexone, 238 to prevent alcohol abuse relapse, 222
Narcotics Anonymous, 239
National Confidential Inquiry into Suicide, 457–459
National Health Service, 555
National Institute of Clinical Excellence (NICE), 639, 652 guideline, 466
National Institute of Mental Health Treatment of
Depression Collaborative Research Program (NIMH
TDCRP), 658
National Service Framework, 350
National Suicide Prevention Project (Finland), 461
National Suicide Prevention Strategy (England), 461
National Treatment Outcome Study, 239
Navajo peoples of North America, 421 needs assessment, after act of self-harm, 468
Needs-Adapted Model, 680 nefazodone for depression in Parkinson’s, 332 sexual side effects, 404 negativism, in catatonia, 30
NEO Personality Inventory, 404 neologisms, 32 in schizophrenia, 284 neonaticide, 440 nervios, 424 nest therapy (nidotherapy), 144
Neuregulin 1 (NRG1), and schizophrenia, 297 neurodevelopmental hypothesis of schizophrenia, 301 neurofibrillary tangles (NFT) in Alzheimer’s disease, 75, 359
PET radiotracers targeting, 75
Neuroleptic Malignant Syndrome (NMS), from antipsychotics, 590, 592 neurological disease, and depression treatment, 521 neurological nutritional deficiency syndromes, in alcohol abusers, 205
Neuropsychiatric Inventory, 359 neuropsychiatry, 320 clinical assessment, 321 electrodiagnostic techniques in diagnosis, 324 neuroimaging, 325
‘organic’ and alternatives, 320 physical examination, 324

neuropsychological assessments, of children, 98 neurosis, 46 gender and, 372 in old age, 372–373 treatment, 373 neurosyphilis, and dementia, 339
‘neurotic’, 41
‘neuroticism’, and sexuality, 404 neurotoxicity, of cocaine, 233 neurotransmitter, 571
New Zealand, lifetime prevalence of suicidal ideation, 464 nicotine dependence, alcohol and, 222 nidotherapy (nest therapy), 144 for personality disorder, 143 nihilistic delusions, 26, 252 nitric oxidase-arginine-NO-cyclic GMP pathway, 400
N-methyl-D-aspartate (NMDA) receptor, hypofunction of, and schizophrenia, 588 nocturnal enuresis, 105 nocturnal penile tumescence (NPT), 401 non-competitive antagonists, 572 non-contact child sexual abuse, 101 non-governmental agencies, integration with other services, 506 non-Mendelian modes of inheritance, 82 non-parametric linkage, 89 non-Western cultures, assumption about, 425 noradrenaline (NA), and mood, 264 noradrenergic (NA) system, in GAD, 150 noradrenergic system, 153 nordrenaline, 624 normal distribution, of continuous variable, 62 normal pressure hydrocephalus, and dementia, 338 normality, cultural concepts of, 422 nortriptyline, 265, 625 nutritional deficiency syndromes, neurological, in alcohol abusers, 205 nutritional management, 186 obesity, 193 eating disorders and, 182 object relations theory, 666 countertransference and, 670 objectivity in emotion, 11 observation by therapist, in psychodynamic psychotherapy, 668 observational analytic studies, 56 when to use, 57 observational descriptive studies, 54, 56

719

720

Index

observational study designs, 54 obsessions, 163 obsessive and compulsive phenomena, 17–19 obsessive-compulsive disorder (OCD), 148, 149, 163–169 age and, 372 anorexia nervosa and, 183 biological basis, 165 brain lesions and, 333 children and, 124 common subtypes, 164 contraindication for dynamic therapy, 675 course and co-morbidity, 164 epidemiology, 163 in maintenance phase of psychosis treatment, 604 management, 167 medical causes of symptoms, 333
Obsessive Compulsive Spectrum, 164 pathogenesis genetics, 166 neurochemistry, 166 neurocircuitry, 166 pathogenesis, 165–167 pharmacotherapy, 167 phenomenology and diagnosis, 164 psychotherapy, 168 sexuality and, 404 obsessive-compulsive disorder (OCD), SSRI for, 634 obsessive-compulsive disorder (OCD), symptom severity rating, 164 obstetric complications and aggression, 549 and schizophrenia, 298, 303 occupation and day care, in mental health services, 505 occupational rehabilitation alternatives, 508 for schizophrenia, 310 occupational therapy assessments, for children, 98 occupations, and alcohol-related problems, 213
Odds Ratio (OR), 60, 61 oesophagus, cancer, chronic alcohol consumption and,
207
oestrogen, 401, 442 for depression in perimenopause, 442 oestrogen, for Alzheimer’s disease, 443
Offender Group Reconviction Scale (OGRS), 553 olanzapine, 301, 363, 587 dyslipidemia and, 593 for affective psychosis, 607 for aggressive patient with psychosis, 602

for depressive episode in bipolar disorder, 608 for psychotic depression, 611 for psychotic relapse prevention, 603
Neuroleptic Malignant Syndrome from, 592 pharmacology, 589 plasma prolactin levels, 594 side effects, 591 starting doses for elderly, 364 weight gain from, 593 old age affective disorders depression, 366–369 affective disorders, 366–370 alcohol abuse in, 374 anxiety disorders in, 373 bipolar disorder, treatment, 610 changes affecting population, 350 delirum in aetiology, 365 course and outcome, 365 epidemiology, 365 management, 365 delirum in, 364–366 dementias, 352–364 depression in aetiology, 367 and cerebrovascular disease, 368 epidemiology, 366
IPT for, 659 treatment, 368–369 depression in, 366–369 learning disabilities in, 375 mania in aetiology, 369 clinical features, 370 treatment, 370 mania in, 369–370 memory clinics, 352 mental health services, 351 liason with general hospital, 351 neurosis in, 372–373 post-traumatic stress disorder (PTSD), 373 primary care, psychiatric disorders, 480 psychiatry, 351, 353, 355, 357, 359, 361, 363, 365, 367,
369, 371, schizophrenia in, 605 senile self-neglect, 374 social deprivation indices relevant to, 350 somatisation in, 373

Index

suicide in, 373 very late onset schizophrenia aetiology, 371 cognitive function, 371 epidemiology, 371 management, 372 symptoms, 371 very late onset schizophrenia, 370–372 older people community care of, 350 day hospital care of, 351 inpatient care, 351 olfactory hallucinations, 8 oligogenic models, in gene finding, 88 omission, in schizophrenic language disorder, 35
OPCRIT computerised scoring system, 48 percent agreement and kappas for operational criteria,
48
operant conditioning model of alcohol use, 214 operational definitions, advantages and disadvantages,
47–49
operational diagnostic process, vs. clinical situation, 48 oppositional defiant disorder, 113 oral absorption, drug release rate for, 567 oral cavity, cancer, chronic alcohol consumption and, 207
‘organic mental disorders’, 326 orgasm, 400 difficulty for women, 407 orthostatic hypotension, from antipsychotics, 594
Othello syndrome, 291 outcome, associations between exposure and, 60 out-patient/ambulatory clinics, 503, 506 overconclusiveness, in meta-analysis, 67 over-inclusion, 33 overvalued ideas, in delusions, 24 oxazepam, starting doses for elderly, 364 oxcarbazepine, 599 for affective psychosis, 607 paediatric autoimmune neuropsychiatric disorders, 166 paedophilia, 411
DSM-IV numeric code, 43 pain, chronic, antidepressants for, 529 pairwise concordance rate, 83
Pakistan, depression after birth of female child, 427 pancreatitis, alcohol misuse and, 207
PANDAS, and paediatric autoimmune neuropsychiatric disorders, 166

panic attacks, 147, 152 cannabis use and, 231
DSM-IV-TR criteria, 148 from amphetamine use, 235 in epilepsy, 347
Parkinson’s and, 332 panic disorder (PD), 149, 152–155 benzodiazepines and, 632 management, 154 pathogenesis, 153 pharmacotherapy, 154 phenomenology and diagnosis, 152 psychotherapy, 155 sexual problems in, 401 suicide risk and, 457 paracetamol, self-harm with overdose, 465 paranoia, confabutory, 27 paranoid personality, 291 paranoid psychosis amphetamine use and, 235 cocaine use and, 233 paranoid schizophrenia, 285 paranoid states, vs. schizophrenia, 291 paraphilias, 397, 410 paraphrenia, 285 late, 370–372
‘parasuicide’, 463 pareidolia, 9 parent training programmes, 118 parent-child relationships attachment, 102 conduct disordered child and, 114 disturbances in infancy, 102 parents, loss in childhood, and depression risk, 271 parkinsonism and obsessive-compulsive symptoms, 166 medication-induced, 592
Parkinson’s disease and anxiety, 333
DBS treatment for, 629 dementia in, 338 depression and, 270, 332, 367, 519–521 depression treatment and, 521 dopamine deficiency in, 302
DSM-IV numeric code, 43 paroxetine, 265, 623 for personality disorder, 143
PET for study, 71 partial agonists, 572

721

722

Index

passivity experiences, depersonalisation distinguished from, 29 passivity phenomena, 27 pathophysiology, 68
‘pathways to care model’, 480
Patient Health Questionnaire-9, 522 patient history, 44 family history, 682 family involvement in problem, 684 for dementia assessment, 355 with physical and psychiatric illnesses, 483 patients, therapist relationship, 667
PCL:SV (Psychopathy Checklist Screening Version), 553 peer groups and alcohol dependence, 213 and antisocial behavior, 115 pellagrous encephalopathy, 338 penetrance, incomplete, 87 penile erection, 400 pentagastrin, for SAD, 157 peptic ulcer, alcohol misuse and, 207 perception abnormalities in schizophrenia, 306 delusional, 23 in depersonalisation, 30 in mania, 16 vs. sensations, 6 perceptual disorders agnosias, 6 false perceptions, 7 micropsia and macropsia, 6 synaesthesia, 6 perceptual disorders, 6–10 perfectionism, in obsession, 18 perfectionistic personality style, and motherhood, 435 perimenopause, 441 perinatal depression, 438 peripheral neuropathy, in alcohol abusers, 205 perisylvian brain atrophy, 336 permanence, in severe depression, 14 perphenazine, for psychotic relapse prevention, 603 persecution experienced in depression, 14 feelings of, 28 persecutory world view, 25 perseveration, 32 persistent post-concussional syndrome (PCS), 346 personal (episodic) memory, 322 personal construct theory, 637

Personality Assessment Schedule, 140 personality change, after stroke, 344 personality disorder aetiology, 141
Chinese populations, 424 classifying by attribution, 141 by category, 135–138 by cluster, 137 by impact on social functioning, 140 by severity, 138 general attitudes concerning, 135 impact on sexual intimacy, 404 in ICD-10, 42 medical condition impacting, 333 self-harm risk, 465 suicide risk and, 457 treatment drugs, 142 psychotherapy, 142 treatment, 141–144 violence and, 546–548 personality model of SAD, 157 personality traits, and depression, 273 pessimism, and 5HT2a binding potential, 71 phaeochromocytoma, and depression treatment, 521 pharmacodynamics, 579 pharmacodynamics, 571–576 pharmacogenetics antipsychotic response prediction, 580 antipsychotic treatment, 578 antipsychotics adverse effects, 580 candidate genes, 580 dopamine receptors, 579 ethical concerns, 581, 582 limitations of studies, 582 serotonin receptors, and antipsychotic action, 567 pharmacogenetics, 578–582 pharmacokinetics, 579 absorption, 567 distribution, 567–568 elimination, 569 metabolism, 568 pharmacokinetics, 567–571 pharmacology, behavioural, 576–578 pharynx cancer, chronic alcohol consumption and, 207 phencyclidine (PCP; ‘angel dust’), and psychotic state, 303 vs. schizophrenia, 290

Index

phenelzine, 627 for SAD, 159 phenocopies, 87 phenomena, 44 phenomenological psychopathology, 44 phenothiazines, 587, 588 phenylalkylamines (mescaline, ‘STP’), 328 phobia, and obsession, 17 phosphodiesterase V inhibitors, and erectile function, 408
[11 C]PIB (Pittsburgh Compound-B), 76
Pick bodies (cytoplasmic basophilic inclusions), 336 pimozide and prolonged QTc, 594 for delusional parasitosis, 607 pindolol, 604 piperazine class of phenothiazines, 589 piperidine class of phenothiazines, 589
Pittsburgh Compound-B ([11 C]PIB), 76 pituitary hormones, in affective disorders, 268 placenta, medications crossing, 170 plaques, in Alzheimer’s disease, 359 plasma levels for antipsychotics, 590
Asians vs. Europeans, 578 plasma protein-binding displacement interactions, 568 plasma proteins, drug’s relative binding affinity to, 568 pleasure, 10
PMDD (premenstual dysphoric disorder), 434, 436–438
PND (postnatal depression), 438
IPT for, 660 poisoning, self-harm by, 464 polygenic statistical model, 82, 87 liability-threshold, 83 polymorphisms, providing predictive value of response to clozapine, 580 population attributable fraction, 90 population mental health, 429 population, morbidity force of a disease in, 53 porphyria, and depression treatment, 521 positional cloning, 88 positron emission tomography (PET), 69, 71 for Alzheimer’s disease, 74 for depression, 70, 72 in neuropsychiatry, 325, 326 schizophrenia studies, 74 schizophrenia studies, 73 possession, delusions of, 26 post-ejaculatory refractory period, 400 postnatal depression (PND), 438
IPT for, 660

post-partum period, anxiety symptoms in, 170 post-traumatic stress disorder (PTSD), 149, 159–163 approach to treating, 163 children and, 123 cognitive models, 642 course, 160 diagnosis/phenomenology, 160 epidemiology, 160 management, 162 old age, 373 pathogenesis, 161 pharmacotherapy, 163 prevention, 162 psychotherapy, 163 refugees, 428 symptom clusters, 161 posturing, in catatonia, 30 potency, of drug, 572 poverty gender and, 427 mental disorders and, 426 psychopathology and, 431
Poverty of Language, 33, 35
Prader-Willi syndrome, 385, 386 catatonia in, 332 pragmatics, schizophrenic speech as, 32 pramipexole, for depression in Parkinson’s, 332 preconscious, 666 predictive animal models, 576 pregabalin, for GAD, 151 pregnancy alcohol consumption during, 208 anxiety disorders in, 169, 435 bipolar disorder treatment during, 611 denying, 440 depression during, 435
IPT for, 660 maternal smoking, and aggression, 549 medications in, 441 psychotic disorder treatment during, 605 schizophrenia and, 298 premature ejaculation (PE), 407 premenstrual mood disorders, 434 premenstual dysphoric disorder (PMDD), 434, 436–438 prenatal viral infection, and schizophrenia, 299 prescriptive message, in family therapy, 687 presenilin 1 (PS1; chromosome 14) and Alzheimer’s disease, 354 mutations, 335, 360

723

724

Index

Present State Examination (PSE/CATEGO), 50, 287 pressure of talk, 34 prevalence, 59 primary care, 479 case-finding, 484 counselling in, 489 interface with psychiatry, 486
IPT in, 660 mental health care provided by, 500 with specialist backup, 502 mental health skills training for professionals, 487 nurses’ role, 491 psychiatric disorders, 479 as burden, 482 classification, 481–482 detection, 482 factors affecting recognition, 483 management, 488 outcome improvement, 485 prognosis, 482 shared care with mental health services, 487 suicide and, 491
Primary Care Practice Guidelines, 652 primary delusions, 22 primary incontinence, 104 primary mental disorders, 326 prion diseases, and dementia, 339 prison, for drug-related offences, 241
‘Pritchard’s Criteria’, 557 probands in family studies, 81 risk of disease in relative of, 82 probandwise concordance, 83 problem-solving therapy for personality disorder, 143 use in primary care, 489 procedural (implicit) memories, 322 process schizophrenia, 288 prodromal services, managing risk of conversion to psychosis, 311 progestagens, for illegal sexual behaviors, 411 progressive muscle relaxation (PMR), 155
Progressive Supranuclear Palsy (PSP,
Steele-Richardson-Olszewski syndrome), 337 prolactin, 405 elevated, from antipsychotics, 594 pituitary release, 268 propranolol for akathisia, 592 starting doses for elderly, 364

protective factors, in childhood psychiatric assessment,
98
pseudo-bulbar palsy, 206 pseudo-cholinesterase, 628 pseudodementia, dementias and, 354 pseudohallucinations, 9
PSP (Progressive Supranuclear Palsy;
Steele-Richardson-Olszewski syndrome), 337
Psychiatric Assessment Schedule for Adults with
Developmental Disabilities (PAS-ADD) checklist,
389
psychiatric disorders, 80 alcohol and, 222 cocaine use and, 233 in hospitals consequences, 517 frequency, 515, 516 inadequacy of services, 518 unrecognised and untreated, 517 operational definitions, 47 suicide and, 455 symptoms, 3 traditional boundaries between categories, 276 violence and prevalence, 540 violence and community prevalence studies, 541 psychosis among criminal offenders, 541 relative or absolute risk, 544 risk factors, 541 violence and, 540–544 psychiatric genetics, 92 major paradigms, 81 psychiatric hospitals, 505 psychiatrists and psychiatric beds, Europe vs. African countries, 500 psychoactive substance, mental and behavioural disorders due to, 41 psychoanalytic theories of mental illnesses and personality in depression origin, 272 vs. genetic influences, mid-20 c. views, 81 psychoanalytical movement, terminology development,
46
psychoanalytical theory, 45 psychodynamic psychopathology, 45 psychodynamic psychotherapy, 665 basic principles, 665 conditions benefiting from, 675 core concepts, 665

Index

indications and contraindications, 674–675 research obstacles to conducting, 673 research, 673–674 subtypes by duration, 665 technique of long-term countertransference, 669 resistance, 670 therapeutic frame, 667 therapeutic interventions, 667 transference, 668 working through and termination, 671–672 technique of long-term, 666–672 technique of short-term, 672 theoretical models, 665 psychogenic, 41
‘psychological autopsies’, 456
Psychologie der Schizophrenen (Schneider), 35 psychomotor disturbance, in depression, 253 psychomotor retardation, in depression, 251
‘psychopathic’, 45 psychopathology and poverty, 431 child abuse as risk factor for, 100 cognitive model of, 637 different schools of, 44 nature of risk, 98 psychopathy, 546 vs. antisocial personality disorder, 545
Psychopathy Checklist Revised (PCL-R), Hare’s, 546
Psychopathy Checklist Screening Version (PCL:SV), 553 psychosis, 46 affective, treatment, 607–611 and epilepsy and schizophrenia-like psychosis (SLP),
347
biological treatment, 586 additional considerations, 604 biological treatment implementation acute phase, 601 first episode treatment, 602 prodromal period, 601 relapse prevention and maintenance phase, 603 chronic cannabis use and, 232 cognitive behavioural therapy (CBT) for, 644 cognitive models of, 642 dopamine release and, 303 dopaminergic function in episode, 73 early identification and treatment of first episode, 311 electroconvulsive therapy (ECT), 605

family life after, 304 government policies for patients with, 311 grey matter abnormalities, 301
HIV brain infection and, 345 management, 307 perinatal, mother and child safety, 440 postpartum episode, 438 primary care management of, 491 stroke and, 344 psychosis of association, 27 psychosis/violence causal pathway, hypotheses, 549 psychosocial assessments, of children, 97 psychosomatic, 41 psychotherapy for binge eating disorder, 192 for bulimia nervosa, 191 for cocaine dependence, 234 for GAD, 152 for personality disorder, 142
‘psychotic’, 41 psychotic behaviours, 46 psychotic depression, treatment, 611 psychotic episodes, and stress, 304 psychotic illness
19th c. classification, 45 medical condition impacting, 328 psychotropic agents for intellectual disabilities, 391 sexual side effects, 405 starting doses for elderly, 364 publication bias, in meta-analysis, 67 puerperal psychosis, 438
Puerto Rico, lifetime prevalence of suicide attempts, 464 pulmonary embolus, and anxiety, 333 qigong-induced mental disorder, 425
QTc prolongation, from antipsychotics, 594 quantitative EEG (QEEG), 325 quetiapine, 587 and weight gain, 593 cataract formation, 596 dyslipidemia and, 593 for affective psychosis, 607 for psychotic relapse prevention, 603
Neuroleptic Malignant Syndrome from, 592 pharmacology, 589 plasma prolactin levels, 594 side effects, 591 starting doses for elderly, 364

725

726

Index

race, 420 racism, 420 radiolabelled receptor binding agents, for SPECT imaging,
326
radiopharmaceutical, 325 randomisation, to control for confounding, 65 randomised controlled trial, 57 ethical concerns, 58 rapid eye movement (REM) sleep, 269 erection during, 401 rapid-cycling bipolar disorder treatment, 607, 608 with lamotrigine, 610 with valproate, 610
Rational Emotive Behavioural Therapy (REBT), 638 rational emotive therapy (RET), 637, 638 rats, with ‘congenital helplessness’, 261 reactive attachment disorder, 121 reactive inhibition in sexual arousal, 399 and response problems, 408
Read code system, 481 reality orientation, 361 reality, and delusions, 25 reason, delusion and, 19 reboxetine, 265, 625 sexual side effects, 404
Receiver Operator Characteristics (ROCs), 553 receptive language disorder, 112 receptors, 571 recklessness, in mania, 254 rectum, chronic dilation, from retentive soiling, 104 recurrence risk, 82 reduced REM latency, 269 redundancy, in schizophrenic language disorder, 33
“reflecting team dialogue”, 679 refractory (treatment resistant) depression, 369,
630
in old age, 368 refugees, mental disorders, 428 relapse prevention of alcohol abuse, 221 of bipolar disorder, 609 of depression, 631 of psychosis, 603 relationships in family, 684 relative risk ratio, 82 relaxation therapies for GAD, 152 for panic disorder, 155

reliability, or validity, 5 religious belief, and delusions, 21 reminiscence therapy, 361 remoxipride, 587 repetitive strain injury, 527 reproduction, and mental health, 430 reproductive disorders, in alcohol abusers, 208
Research Diagnostic Criteria, 47 research methods for examining violence/psychosis relationship, 540 hypotheses development, 53–54 interpreting associations, 64 validity of association, 64 processing results analysis of association, 60–64 analysis of disease frequency, 59 processing results, 59–64 study design, 54 choices, 54–59 suitability level, 59 research strategies, goals, 70 reserpine, 587 reservoir for drug, 568 residential care long-term community-based, 505 alternatives, 508 resilience in childhood psychiatric assessment, 98 of children and adolescents, 98, 99 resistance, 670 response variable, 60 restitutive factors, in childhood psychiatric assessment,
98
restricted affect, 12 restriction, to control for confounding, 65 retentive soiling, in childhood, 104
Rett syndrome, 112 reversible inhibitors of monamine oxidase (RIMAs), for
SAD, 158 rigidity of emotional responses, 12 risk factors in childhood psychiatric assessment, 98 for psychopathology, 98 risk assessment evaluating utility of instruments, 553 generalisability, 553 intervention decision, 554 predictive validity, 553 for future self-harm, 468

Index

in forensic psychiatry, 551 for violence, 554
Risk Ratio (RR), 53, 60, 61 risperidone, 363, 587 dyslipidemia and, 593 for first psychotic episode treatment, 602 for psychotic relapse prevention, 603 in combination for aggression, 602
Neuroleptic Malignant Syndrome from, 592 pharmacology, 589 plasma prolactin levels, 594 side effects, 591 starting doses for elderly, 364 weight gain, 593 rituals, autistic, 111 rivastigmine, 362, 363 role disputes, IPT for depression from, 657 role transition, IPT for depression from, 657 romantic jealousy, 11
Royal College of Psychiatrists, 652 guideline, 466 ruminative thinking style, and childhood depression, 119 rural life, and suicide risk, 454 sadness, in depression, 15 same-gender attraction, 397 sample mean, variability of, 63
[11 C]SB-13 PET tracer, 76
Schedules for the Clinical Assessment of Neuropsychiatry
(SCAN), 49, 258 schema-focused therapy, 638 schizoaffective disorder, 288 treatment, 606 schizophrenia, 5 abuse and victimisation as risk for, 305 alcohol misuse and, 204 and pregnancy, 438 and violence, 541 animal models, 577 antecedents of, 303 autism vs., 109 biological abnormalities in relative, 297 borders of, 288 brain imaging studies for, 71–73 brain structure and function, 300–302 chronic, lack of emotional responsiveness, 12 classical subtypes, 285 concept criticism, 287 concept development, 285

current classification, 290 diagnosis hearing voices in, 7
ICD 10 vs. DSM-IV criteria, 289 symptoms, 286 differential diagnosis, 290 illicit drugs and psychosis, 290 organic causes, 291 paranoid states, 291 dopamine hypothesis of, 587
PET imaging and validation of, 73
DSM-IV numeric code, 43 early environmental hazards, 298–300 early onset, 112
ECT for, 606 epidemiology, 292–293 genetics adoption studies, 295 models, 296 molecular genetics, 297 relatives lifetime expectancy, 293 twin studies, 294 genetics, 293–298 glucose dysregulation risk in, 593 homicide and, 541
ICD 10 on, 41 in menopause, 442 treatment, 443 language in, 32 terms to describe difficulties, 35 language in, 34–36 management, 308 assertive treatment, 312 cognitive behavioural therapy, 308, 309 crisis intervention, 313 dual diagnosis interventions, 312 family therapy, 309, 310 home treatment, 313 psychological treatments, 308 psychosocial intervention, 308 service-level interventions, 310 social environment impact, 309 social skills training, 310 vocational and occupational rehabilitation, 310 with antipsychotic drugs, 307 management, 307–313 negative symptoms, 284 neuroimaging findings, 74
OCD and, 165

727

728

Index

schizophrenia (cont.) operational definitions, 287 outcome, 306 parenting by women with, 440 primary care and, 491 psychiatric disorders and, 540–544 psychological research in, 305 psychosis as dimension, 289 putative susceptibility genes for, 90 serotonin and, 588 sexuality and, 404 social factors, 303 stupor in, 31 substance misuse and, 312, 604 suicide and, 457, 459 treatment resistant, 603, 604 clozapine for, 604 very late onset aetiology, 371 cognitive function, 371 epidemiology, 371 management, 372 symptoms, 371 very late onset, 370–372 schizophrenia-like psychosis (SLP), and epilepsy and psychosis, 347 schizophreniform disorder, 288, 329
Schnauzkrampf, in catatonia, 30
Schneider, Carl, Psychologie der Schizophrenen, 35
Schneider, Kurt, criteria for differentiating schizophrenia from other conditions, 286 school-refusal anxiey disorder, 122
Scientist-Practitioner approach, for clinical practice, 647 sclerosis, disseminated, 10 seasonal affective disorder (SAD), 253, 268 light therapy for, 629 seasonality, and suicide risk, 454 second messenger action, schematic model, 572 secondary cases, in family studies, 81 secondary delusions, 22 secondary depression medical disorders and substances associated with, 331 treatment, 331 secondary incontinence, 104 secondary mental disorders, 326, 327 secrecy in childhood onset OCD, 124 in family therapy, 688 segregation, 509

segregation analysis, complex, in gene finding, 88 seizures from alcohol withdrawal, 205 preventing, 220 selection bias, 64 selective mutism, 112 selective serotonin re-uptake inhibitors (SSRIs), 609, 623 clinical notes, 623 for autistic spectrum disorders, 392 for depression in old age, 368 for depression in Parkinson’s, 332 for generalized anxiety disorder (GAD), 151, 632 for OCD, 166, 167 for panic disorder, 154 for PMDD, 437 for psychotic depression, 611 for SAD, 158 nausea and anorexia from, 523 risk in pregnancy, 170 sexual side effects, 404 starting doses for elderly, 364 with mirtazepine, 631 selegiline, for depression in Parkinson’s, 332 self psychology, 666 self, beliefs about, 641 self-consciousness, in delusions, 23 self-disclosure, about countertransference, 670 self-harm, 385, 451 aftercare and interventions, 469 clinical factors, 465 compulsory treatment, 468 multidisciplinary teams, 469 overnight admission facilities, 468 epidemiology, 464 international comparisons, 464 hospital services for, 466 management, 467 recommendations, 466 methods, 464 outcome mortality from natural causes, 467 repetition rate, 467 sociodemographic factors, 465 suicide and, 455 self-harm, 463–470 self-help groups, 239 self-medication hypothesis, of addictive substances, 215 selfobject functions, 666 semantic dementia, 336

Index

semantic memory, 322 semantic-pragmatic disorder, 112 seminal emission, 400 senile self-neglect, 374 sensations, vs. perceptions, 6 sensitive self-reference, in delusions, 23 sensory deprivation procedures, 10 sensory modalities, 6 disturbances in, 6 hallucinations subdivided by, 7 sensory pathways, event-related potentials (ERPs) for evaluating, 325 separation anxiety disorder aetiology, 123 features, 122 separation anxiety disorder, 121–123 separation, animal studies, 261 serotonergic agents, OCD response to, 166 serotonergic neurons, in GAD, 150 serotonergic system, and panic disorder, 153 serotonin (5-hydroxy-tryptamine; 5-HT), 264 and schizophrenia, 588 dysregulation in PMDD, 435 serotonin binding, post-mortem studies, 265 serotonin receptors, and antipsychotic action, 567 serotonin transporter (5HTT), radiolabelled ligand for, 71 sertindole, 587 dyslipidemia and, 593 pharmacology, 589 prolonged QTc and, 594 side effects, 591 weight gain, 593 sertraline, 623 for childhood OCD, 125 for depression, 523 for perinatal depression, 439
PET for study, 71 starting doses for elderly, 364 severity, personality disorders classified by, 138
‘sex addicts’, 403 sex therapy, 409 sexual abuse as self-harm risk, 465 mental disorders and, 551 sexual abuse of child, 100, 411 and chronic constipation, 104 and depression as adult, 272, 427 and mental health, 406 sexual arousal, psycho-physiology of

excitation system, 399 hormones’ role, 400 inhibition system, 399 inhibitory tone vs. reactive inhibition, 399 orgasm, 400 peripheral mechanisms, 400 sexual arousal, psycho-physiology of, 398–401 sexual assault, and mental health, 406 sexual behaviour, 396 impact on mental health, 406 in mania, 16 unusual preferences, 397 sexual development, 395–398 sexual dysfunctions clinical management, 408 drugs causing, 626
DSM-IV numeric code, 43 from antipsychotics, 594
‘Out of control’ sexual behaviour, 410 sexual intercourse, age at first, 397 sexual intimacy, 398 personality disorder and, 404 sexual offenders, 411 sexual orientation, 397 sexual responsiveness, 395 clinical management of problems, 407–410 medication side effects, 404, 405 problems from dual control perspctive, 408 sexuality, 395 gender and, 411 mental health impact on, 401–404 schizophrenia and, 404 shared care, mental health services and primary care, 487 shared family envrionment, twin studies and importance of, 84 shifted out patient model, 486 short-sequence repeat (SSR) markers, 88 short-term (working) memory, 322 sibutramine, for binge eating disorder, 193 sick building syndrome, 527 sickle cell disease, and depression treatment, 521 signal/noise ratio, 63 sildenafil, and erectile function, 408, 409 similes, in language disorder, 32 simple delusions, 24 simple depression, 13 simple schizophrenia, 285 single major locus model, 87 single nucleotide polymorphisms (SNPS), 90

729

730

Index

single photon emission computed tomography (SPECT),
325
single session debriefing techniques, for PTSD, 162 skeletal muscle myopathy, alcohol-related, 208 skin disease, in alcohol abusers, 208 sleep and brain physiology, 269 phase between waking state and, 10 rapid eye movement (REM), 269 erection during, 401 sleep disturbance
DSM-IV numeric code, 43 in depression, 15, 251 in mania, 16 slope, in drug response, 572
Slovakia, 509
Slovenia, 509 small studies, in meta-analysis, 67
Smith Magenis syndrome, 391 smoke from cannabis, and cancer, 231 smoking cocaine, health impact, 234 smoking tobacco by mother, during pregnancy, and aggression, 549
‘snorting’ cocaine, health impact, 234 social adversity, and mental health, 430 social anxiety disorder (SAD), 149, 156–159, 642 developmental models, 157 diagnosis, 156 in children, 122 management, 158 pathogenesis, 157 pharmacotherapy, 158 psychotherapy, 159 social attention rule, 114 social class and depression, 259 suicide rate, 453 social control theory of drug use, 214 social deficits, in autism, 110 social deprivation indices, relevant to older people, 350 social development model of drug use, 214 social disinhibition, in mania, 254 social environment, impact on schizophrenia outcome,
309
social functioning impact, personality disorders classified by, 140 social isolation, and suicide risk, 457 social learning theory of drug use, 214

social phobia, 149
SSRIs for, 633 social psychiatry, 498
Social Rhythm Index (SRI), 661 social services/welfare benefits, integration with other services, 505 social support, lack for migrant labourers, 427 sociological behaviour models of suicide, 460
Socratic questioning, 639, 640 sodium valproate, for mania in elderly, 370 somatic hallucinations, 8, 10 somatisation, 484, 524 features, 533 in old age, 373
South Asia, children, cultural value of boys vs. girls, 427 specialist services, responsibilities in mainstream care, 503 specific phobia (SP), 169
SPECT (single photon emission computed tomography),
325
speech accelerated tempo, 34 illogical, in schizophrenia, 284 in mania, 254 speech disorder, 31 speech therapy assessments, of children, 98 sperm counts, alcohol consumption impact, 208 spirits, possession by, 26 spiritual causes of illness, 424 spironolactone, for PMDD, 437 ß-blockers, 363 for akathisia, 592 starting doses for elderly, 364
St Louis criteria, 47 staffing for residential care, 508 stalking, 18 standard error (SE), 63 standard of living, and depression, 426
Standardised Mortality Ratios (SMRs), 456 starvation impact of, 186 physical consequences, 185 statistical significance of association, 64 statistical tests, in gene-finding method, 90 steady-state, in drug-dosing regimen, 569
Steele-Richardson-Olszewski syndrome, 337 stepped-care model for depression treatment, 490 stereotactic surgery, for OCD, 168

Index

stereotopy, 32, 35 stereotyped movements, in catatonia, 30
Stevens-Johnson type syndrome, lamotrigine and, 600 stigmatisation, 510 stimulant psychosis, medical condition impacting, 329 stimulus-response model, 637
‘stolen generations’, 429
‘STP’ (mescaline, phenylalkylamines), 328 strange situation, child’s reaction in, 666
Strategic Therapy (Hay), 679 stratified analysis, 66 strength of association, in cause-effect relationship, 66
Streptococcus, and paediatric autoimmune neuropsychiatric disorders, 166 stress and high alcohol intake, 213 depression and, 270 in developing countries, from debt to loan sharks, 430 perceptual disturbances in, 10 psychotic episodes and, 304 stress reactions, DSM-IV numeric code, 43 stress-diathesis model of suicide, 461 stress-vulnerability model of suicide, 461 stroke patients, 343 depression in, 270, 367 structural equation model (SEM) for twin data, 85
Structural Family Therapy (Minuchin), 679 study population, bias in selection, 65 stupor, 31 stuttering, 31 subarachnoid haemorrhage, and personality change, 334 subcortical dementias, 336 substance misuse and anxiety disorders, 170 and suicide risk, 457
DSM-IV numeric code, 43 in general hospital settings, 532 in PTSD, 161
IPT for, 661 schizophrenia and, 312, 604 suicide risk, 460 violence and, 545 substitution, in schizophrenic language disorder, 35 succinylcholine, 605 suicidal dispair, 14 suicidal thoughts in depression, 252
Parkinson’s and, 332

suicide adverse life events, 455 affective disorders and, 459 after deliberate self-harm, 467 behaviour models, 460 clinical, 461 sociological, 460 biological factors, 454 definitions and case ascertainment, 451 depression treatment and, 463 environmental factors, 454 seasonality, 454 urban or rural life, 454 epidemiology, 451 epileptic patients, 347 features predictive of, 252 hospital admission to prevent, 458 in HIV patients, 345 in India, 430 international comparisons, 451 trends in rates, 452 media representation, 462 mental disorders and, 457 methods, 453 old age, 373 preventing, 462 high risk and population approaches, 461 reducing availability of methods, 462 strategies, 461 preventing, 461–463 prevention helplines, 470 primary care and, 491 psychiatric disorder and, 455 cohort studies, 456 rates by country, year and gender, 452 risk in bipolar disorder, 275 risk in depression, 276 schizophrenia and, 459 schizophrenia diagnosis as risk for, 307 self-harm and, 455 sociodemographic factors age, 453 ethnicity, 454 gender, 453 marital status and children, 454 social class and employment, 453
SSRIs and, 624 treatment, pharmacotherapy, 463 suicide, 451–463

731

732

Index

sun-downing syndrome, 344 superego, 666 supernatural causes of illness, 424 supervised injecting facilities (SIS), 238 supportive messages, in family therapy, 687 supportive-expressive psychodynamic therapy, for GAD,
152
suprachiasmatic nucleus, 268 survival analysis, 82 susceptibility genes for schizophrenia, 297 vs. genetic risk factors, 82 susto, 423–424
Swedish Temperance Board Studies, 211 symptom, as signpost, 3 synaesthesia, 6 syndromes, not diseases, 45 synonyms, 32 systematised delusions, 25
Systems Theory, 678 tachycardia, from antipsychotics, 594 tactile hallucinations, 8, 10 tag SNP, 90 taijin kyofusho, 423 tardive dyskinesia (TD) from antipsychotics, 580, 592 in elderly, 605 with schizophrenia, 372 tau protein, 75 temperament, 11
Temperament and Character Inventory (TCI), 141,
274
temporal lobe epilepsy, 334 psychiatric aspects, 346 temporal lobes dysfunction, auditory and visual hallucinations in, 10 medial, MRI for detecting volume, 75 volume reduction in, 72 temporal order, in support for causal relationship, 66 temporal variations, in schizophrenia, 292 terminology, preferred, 45 testamentary capacity, 364 testing, neuropsychological assessments, 322 testosterone (T), 400 tetrachoric correlations, 83 tetracyclic antidepressants, for nocturnal enuresis, 106
THC, cannabis user tolerance to, 231
‘theory of mind’, for social interaction, 306

therapeutic alliance, 669 therapeutic communities (TCs) for opioid users, 239 for personality disorder, 143 therapeutic index, 574 therapeutic relationship, and CBT, 640 therapists, patient relationship, 667 thiamine and Wernicke-Korsakoff Syndrome (WKS), 206 and Wernicke’s encephalopathy, 221 thioridazine and prolonged QTc, 594 starting doses for elderly, 364 thiothixene, 588 starting doses for elderly, 364 thought, 28 attempt to study, 31 thought blocking, 28, 34 thought broadcasting, 28 thought control, 28 thought diffusion, 28 thought disorder, in schizophrenia, 284 thought insertion, 28, 286 thought withdrawal, 28 thyroid- stimulating hormone (TSH), 267 thyrotrophin-releasing hormone (TRH), 267 thyroxin (T4), 267 tics, 30
OCD and, 165 time, sense of slowing, 14 tinnitus, 8 toilet training of toddlers, 104 tolerance to benzodiazepines, 575 topiramate, 600 for binge eating disorder, 193 topographic model, of Freud, 665
Tourette’s Disorder, OCD and, 165
Tower of London Test, 305
‘Trailblazer’ programme (UK), 488 transcranial magnetic stimulation (TMS), 370, 606,
629
transference resistances, 670 transference, in short-term psychodynamic psychotherapy, 672 transference-focused psychotherapy, for personality disorder, 143 transgender communities, on Internet, 412 transgenic animal models, 91
Transitory thinking, in schizophrenic language disorder, 35

Index

transmission/disequilibrium test (TDT), 90 transmitter-receptor interaction, schematic model, 572 transsexual, 412 transvestism, 412 transvestite, dual role, 412 trauma and anxiety, 333 brain injury, neuropsychiatric aspects, 346 risk for PTSD after, 161 traumatic encephalopathy, chronic, and dementia, 339 trazodone, 363, 625 starting doses for elderly, 364
Treatment Outcome Program Studies (TOPS), 241
Treatment Outcome Prospective Study, 239 treatment resistant depression (TRD), 369,
630
in old age, 368 treatment resistant schizophrenia, 603 clozapine for, 604 treatment-resisting (Type R) personality disorders, 141 treatment-seeking (Type S) personality disorders, 141 tricyclic antidepressants (TCAs), 625 clinical notes, 626 for depression in Parkinson’s, 332 for GAD, 151 for nocturnal enuresis, 106 for panic disorder, 154 for psychotic depression, 611 pharmacodynamics, 575 risk in pregnancy, 170 risk of mania, 609 sexual side effects, 404 triiodothyronine (T3 ), 267 trimipramine, 575 truancy from school, vs. absenteeism, 122 tryptophan, 268, 435 trytophan hydroxylase, 455 t-test, 61, 63 tuberose sclerosis, and autism, 386 twin studies genetic modeling of, 85 of affective disorders, 262 of alcohol problems, 209 of bipolar disorder, 262 of schizophrenia, 294, 301 of somatisation symptoms, 525 questions addressed by, 86 twin studies, 82–84 two-type model of violence in schizophrenia, 544

Type R (treatment-resisting) personality disorders, 141 treatment, 144
Type S (treatment-seeking) personality disorders, 141 tyramine, 627
Uganda, IPT in, 661
Ultra-Rapid Opioid Detoxification (UROD), 238 ultra-short (iconic or echoic) memory, 322 unconscious, 666 unemployment and alcohol intake, 214 and mental disorder, 505 and self-harm, 465 and suicide, 453 unilateral termination of therapy, 672 unipolar disorder, 250 course and outcome, 275 vs. bipolar disorder, 260
United Kingdom mental health law timeline, 555 mental health legislation, 556 per capita consumption of alcohol, 201 self-harm rates, 464 suicide rate, 452
United Nations Principles for the Protection of Persons with Mental Illness and the Improvement of Mental
Health Care, 509
United States forensic psychiatry in, 556 suicide rate, 452
‘universalist’ approach for epidemiological investigations of mental illness, 422 unsystematised delusions, 25 urban life and schizophrenia, 292 and suicide risk, 454 urinary incontinence, in childhood, 105 vagal nerve stimulation, 629 vagina, response during sexual arousal, 400 vaginismus, 407 valid association, 53 validation therapy, 361 validity of association, in research results, 64 or reliability, 5 valproate, 598, 604 for affective psychosis, 607 for depressive episode in bipolar disorder, 608

733

734

Index

valproate (cont.) for rapid-cycling illness, 610 recommended pretreatment tests, 598 valproic acid, for panic disorder, 155 variability in drug response, 572 of sample mean, 63 variable tandem repeat polymorphism (VNTR),
579
variables continuous, 60 continuous, 62–64 dichotomous, 60, 61 vascular dementia, 360 criteria for clinical diagnosis, 357 treatment, 363 vascular depression, 344 hypothesis, 368 vasoactive intestinal polypeptide (VPI), 400 velo-cardio-facial syndrome (DiGeorge Syndrome), 297,
386
venlafaxine, 624, 631 clinical notes, 625 discontinuation syndrome from, 624 for GAD, 151 for perinatal depression, 439 for psychotic depression, 611
PET for study, 71 verbal fluency, testing in schizophrenia, 305 verbigeration, in catatonia, 30 violence affective disorders and, 544 neurobiology of, 548 personality disorder and, 546–548 psychiatric disorders and community prevalence studies, 541 prevalence, 540 psychosis among criminal offenders, 541 relative or absolute risk, 544 risk factors, 541 psychiatric disorders and, 540–544 substance misuse and, 545
Violence Risk Appraisal Guide (VRAG), 552 violence risk assessment, 554 viral infection, prenatal, and schizophrenia, 299 visual hallucinations, 8 causes, 329
Charles Bonnet syndrome, 375 hallucinogens and, 328

visual imagery, in adolescents, 121 vitamin B-6, for PMDD, 437 vocational rehabilitation alternatives, 508 for schizophrenia, 310 voices hallucinated, 7 inner, 9 volition, 30 volitional excitement, in mania, 16 voyeurism, 411
VRAG (Violence Risk Appraisal Guide), 552 vulnerability, maternal loss and, 271 vulvodynia, 408 vulvo-vestibulitis, 408 waking state, phase between sleep and, 10 warfarin, and depression treatment, 521 waxy flexibility (flexibilitas cerea), in catatonia, 30 websites, for depression information, 489 weight gain, from antipsychotics, 593 weight loss, and anorexia nervosa, 182
Wernicke-Korsakoff syndrome (WKS), 206, 338
Wernicke’s encephalophy (WE), 206
Western cultures, research from, 425 wetting and soiling, 104–130 white blood cell count, clozapine and, 595 widowhood, suicide risk, 454 will, 28 hallucinations as independent of, 7
Wilson’s disease, and anxiety, 333 windigo, 423, 424
Wisconsin Card Sort Test, 305 withdrawal state for alcohol-related problems, 199 for drug use, 230 for opioid users, 243
Wittkower, E.D., 420 women depression in, 427 medically unexplained symptoms, 525 menopause Alzheimer’s disease, 442
Alzheimer’s disease treatment, 443 mood disorders, 442 mood disorders treatment, 442 schizophrenia, 442 schizophrenia treatment, 443 menopause, 441–444

Index

mental health aetiology and risk factors genetics, 434 neuroendocrine, 434 psychosocial, 435 mental health aetiology and risk factors, 434–436 perinatal psychiatry postnatal depression (PND), 438 psychosis, 438 treatment, 439 perinatal psychiatry, 438–441 premenstual disorders, 436–438 sexual response problems, 407 suicide, 453 testosterone and sexual arousal in, 401
Women’s Health Initiative Memory Study (WHIMS), 444 word salad, 33 words invention, 32 variety of uses for, 32 working (short-term) memory, 322
World Health Organisation (WHO), 39, 198, 288 consensus view on heroin dependence treatment under coercion, 244
Guide to Mental and Neurological Health in Primary
Care, 481
International Classification of Functioning, Disability and Health, 383
International Pilot Study of Schizophrenia, 46 support for diagnostic interview development, 49

World Psychiatric Association Declaration of Madrid, 509 worries, in children, 121
Xenon-133, 326
Yale Brown Obsessive-Compulsive Symptom checklist, 164
Yerkes-Dodson Curve, 147 young drinkers, risk from alcohol misuse, 201
Zimbabwe, women with depression, 427 ziprasidone, 587 and dyslipidemia, 593 and weight gain, 593 for affective psychosis, 607 for aggressive patient with psychosis, 602
Neuroleptic Malignant Syndrome from, 592 pharmacology, 589 plasma prolactin levels, 594 prolonged QTc and, 594 psychotic relapse prevention, 603 side effects, 591 starting doses for elderly, 364 zolpidem, starting doses for elderly, 364 zotepine, 587 and dyslipidemia, 593 and plasma prolactin levels, 594
Neuroleptic Malignant Syndrome from, 592 pharmacology, 589 weight gain, 593

735

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