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Rheumatoid Arthritis

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Hemophilia
Russell Stoffel
March 25, 2013
C. Engel Biol 101-SA01D
Abstract
Hemophilia is a sex linked inherited bleeding disorder directly linked to the X chromosome, which is responsible for the increased epidemiology in males. Women become carriers and pass it down to male offspring. The person has a decrease or lack of clotting factors in their blood, specifically factors XIII and IX which prevents their blood from clotting properly, causing excessive bleeding.
Keywords: X chromosome, Factor VIII, and Factor IX
Hemophilia
Hemophilia is a condition that has been referenced to throughout history. Although in the second century A.D. they did not know that the excessive and unexplained bleeding after circumcision of male babies was in fact just that, Hemophilia.
In the twelfth century A.D. the disease was linked to one particular village, then to one family. This connection was discussed in writings by Dr. John Conrad Otto.
Through the years many theories about the cause of Hemophilia have been developed, researched, and investigated. The field of scientific research has come far since then leading to in-depth analysis of exactly what the genetic inherited disease Hemophilia is and a better understanding of how to treat it.
Hemophilia is an inherited bleeding disorder in which the affected person’s blood does not clot properly. More specifically, there is something wrong with the gene that codes for clotting proteins in their blood. This causes the patient to end up with little or no clotting factors in their blood. The severity of the disease is directly linked to the amount of clotting factors present. The lesser the amount of clotting factors, the more severe the disease.
There are two main types of hemophilia that represent the majority of people affected by this disease. Hemophilia A and

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