Vitamin D insufficiency is associated with challenge-proven food allergy in infants
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This study has shown a pediatric perspective of food allergy in relation so diseases associated with vitamin deficiency. The aim of the study is to investigate the role of vitamin D in infantile food allergy. Skin prick testing was done to 5276 one-year old infants. Infants with detectible negative prick test results attended a hospital-food challenge clinic. Blood samples of 577 infants were obtained wherein 344 of this samples shows challenge-proven food allergy, 74 sensitized but tolerant to food challenge, 159 negative on skin prick. Using liquid chromatography, serum 25-hydroxyvitamin D levels were measured.
It was found out that infants born of Australian parents, but not born overseas with vitamin D deficiency were more likely to be allergic to peanut and / or egg than those with adequate vitamin D. Furthermore, among them, infants were more likely also to have multiple food allergies rather than single allergy. Hence, results suggest that there is a significant difference between the statuses of vitamin D of infants as to the probability of having certain allergy on food. It can be concluded that vitamin D sufficiency play an important protective factor for food allergy in the first year of life.
Therefore, this study requires immediate action so as to prevent food allergy in infants induced by vitamin D insufficiency in the first year of life.

Spontaneous basophil responses in food-allergic children are transferable by plasma and are IgE-dependent.
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The study is about the association of high spontaneous basophil histamine release (SBHR) to food-allergic (all to cow’s milk) children. Basophils were isolated from the blood of 38 FA and non-allergic children. At the time when the blood was drawn, all the allergic children were strictly. Three of the 18 control subjects did have low levels of milk-specific IgE (1.52 KUA/L).Moreover,13 FA and 10 control subjects’ basophils were investigated for histamine and IL-4 . The investigation shows that 11 of the 13 Fa demonstrated SBHR.
It was confirmed that FA subjects exhibited high SHBR with spontaneous IL-4 secretion .Interestingly, the study demonstrated that SBHR and IL-4 secretion as well as increased CD203c expression, are all transferrable to basophils of non-allergic subjects via passive sensitization using plasma from food-allergic individuals. These markers may or may not have diagnostic significance, but by predicting whether one is at risk of dangerous reactions to milk, recent studies suggest that this may be true.
Therefore, further study is needed so as to validate or with different methods to halt the transfer of expression on allergy from allergic individuals to non-allergic individuals.

The effect of provision of an adrenaline auto-injector on quality of life in children with food allergy
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This study is to serve as to validate the adverse effect of adrenaline auto-injector as management of food allergy. The decision to prescribe an AAI is not fixed and can be reviewed at regular intervals . For example, a child younger that 5 years of age who had not been issued an AAI may later develop poorly controlled asthma or move to a remote geographic location and an AAI could be issued at that time. Therefore, the presence of food allergy can markedly affect the QOL of an individual. By using a validated FAQOL questionnaire , AAI becomes an issue. Hence, it would be better if particular attention be paid to education, training, retraining, and follow-up to minimize the effect of provision of an AAI on an individual with food allergy.