Free Essay

Systemic Lupus Erthematous

In: Science

Submitted By DeezyRae32
Words 982
Pages 4
There is an estimated 1.5 million Americans that have and live with Lupus and more than 16,000 new cases are reported across the country each year (LUPUS Foundation of America; 2011). Lupus is an autoimmune disease that is chronic and can cause damage to any part of the body. The body’s immune system produces proteins referred to as antibodies. These antibodies help to provide protection for the body from invaders. Our immune system cannot tell the difference between these foreign invaders and our body’s healthy tissues; therefore autoantibodies attack and ultimately destroy healthy tissues, which is known as autoimmune or Systemic Lupus Erythematosus (SLE) (LUPUS Foundation of America; 2011). Inflammation, pain, and damage to other various parts of the body are due to these autoantibodies.

The causes of SLE are genes, environment, and genetic factors. Even though researchers and scientists are unsure of just how genetic factors may alter or affect the immune system; researchers estimate that 20 - 100 different genetic factors may make a person susceptible to SLE (The New York Times; 2011). Environmental triggers can set off a flare of this disease. Environmental triggers can be ultraviolet rays from either the sun and/or fluorescent light bulbs, sulfa drugs that causes more sensitivity to the sun, penicillin and other antibiotic drugs, an infection, a cold and/or a viral illness, exhaustion, an injury, emotional stress and anything that causes stress to the body (LUPUS Foundation of America; 2011). Estrogen is a hormone that is produce by both females and males. Due to the fact that females do produce more Estrogen then men, women are more likely to develop Lupus. This is especially true during the times when Estrogen is at its highest levels during pregnancy or before menstrual periods. This does indicate that Estrogen may help regulate the severity levels of Lupus, but it does not necessarily say that hormones are the exact cause of Lupus. Risk factors also have a weight on if someone is affected by SLE or not. The risk factors include sex, age, race, and family history. If you are a woman you are more likely to develop Lupus than a man. There are more than 90 percent of people with Lupus are women. Symptoms and diagnoses are more likely to occur between the ages 15 and 44. African Americans, Hispanics, Latinos, Asian Americans, Native Americans and Hawaiians, and Pacific Islanders are more likely to get Lupus than Caucasian. These races also have a higher chance of developing symptoms at an earlier age as well experiencing a more severity of the disease (LUPUS Foundation of America; 2011). A family history of Lupus causes a 5 to 13 percent for a person to develop this disease.
Due to how Systemic Lupus Erythematosus affects so many different organs symptoms may develop a range that is wide. The most common symptoms which can be the same for females or males are:

Do the fact that these symptoms can appear the same in other illnesses, Lupus has been nicknamed “The Great Imitator” (LUPUS Foundation of America; 2011). Systemic Lupus Erythematosus has great effects on the other systems of the body. SLE can affect the function or functions of the systems of the Cardiopulmonary, Gastrointestinal, Musculoskeletal, Nervous, Renal/Kidney, and Skin,
The Cardiopulmonary System is affected by means of the Heart. Lupus can cause Pericarditis, Myocarditis, Endocarditis, and Coronary Artery Disease. Blood is part of the Cardiopulmonary System and problems with the red and white blood cells and the platelets because a person has Lupus. Problems that can develop in the Blood are: Anemia, Leukopenia and Neutropenia, Thrombocytopenia, and Thrombosis. Vasculitis is the inflammation of the walls of a blood vessel. Inflammation in a small blood vessel, like a capillary, can cause the blood vessel to break and then bleed inside the tissue.
The Lung and Pulmonary System is affected by Lupus by causing Pleuritis, Pneumonitis, Chronic Diffuse Interstitial Lung Disease, and Pulmonary Emboli (LUPUS Foundation of America; 2011).
The Gastrointestinal System is the pathway for the body to take in, process, and disposing of everything that is ingested. Having Lupus can lead to problems with the GI Tract and its surrounding organs such as the liver, pancreas, bile ducts, and the Gallbladder. Lupus can lead to the development of problems that are related to the GI Tract such as Esophageal Disorders in Lupus, digestive difficulties, Ulcerative Colitis and Crohn’s Disease, Peritonitis and Ascites, Pancreatitis, liver complications, and Peptic Ulcers (LUPUS Foundation of America; 2011).
Lupus affects the Musculoskeletal System by possibly bringing inflammation, Lupus Arthritis, Lupus Myositis, Drug-induced Muscle Weakness, Tendonitis and Bursitis, Carpal Tunnel Syndrome, Osteoporosis, and Avascular Necrosis of the Bone (LUPUS Foundation of America; 2011).
The Nervous System is affected by causing problems in the Peripheral Nervous System and Autonomic Nervous System which can lead to the development of Raynaud’s phenomenon, Cognitive Dysfunction, and Lupus Headache. Having Lupus can lead to Lupus Nephritis and infections of the Urinary Tract that are involved with the Renal/Kidney system.
Developing or having Systemic Lupus Erythematosus can lead to the development of skin problems like Subacute Cutaneous Lesions, Chronic Cutaneous Lupus (Discoid Lupus), Acute Cutaneous Lupus, Calcinosis, Cutaneous Vasculitis Lesions, hair loss, Livedo Reticularis and Palmar Erythema, Mucosal Ulcerations, and Petechiae (LUPUS Foundation of America; 2011). All in all, especially to the fact the Lupus has acquired the nickname of “The Great Imitator”; Lupus is to be taken very seriously. If you are experiencing any symptoms of Lupus or you might be worrying that it could possibly be Lupus, it is better to get checked find out as early as possible then finding out when it is too late.

References
Family Doctor; 2010 American Academy of Family Physicians retrieved from http://familydoctor.org on November 5, 2011 LUPUS Foundation of America; 2011 LUPUS Foundation of America retrieved from http://www.lupus.org/ on November 5, 2011

Similar Documents

Premium Essay

Research Paper

...the National Medal for Literature, the Gold Medal for Poetry from the National Institute of Arts and Letters, the Pulitzer Prize, the Bollingen Prize, and the National Book Award. He was awarded a Guggenheim Fellowship, taught briefly at Harvard, and served as Consultant in Poetry for the Library of Congress from 1950 to 1952. He was also largely responsible for establishing Emily Dickinson's reputation as a mayo SWAG SWAG SWAG THIS IS NOT MINE AND I DO NOT TAKE CREDIT FOR THAT. Flannery O’connor Writer. Born on March 25, 1925, in Savannah, Georgia. Flannery O'Connor is considered to be one of the greatest short story writers of the twentieth century. She faced some hardships growing up, losing her father as a teenager. He died of systemic lupus erythematosus, an autoimmune disease. Early on Flannery O'Connor demonstrated her literary talents as a writer for school publications. Studying at what is now the University of Iowa for a master's degree, O'Connor got her first story published "The Geranium" in 1946. She also had begun what was to be first novel, Wise Blood (1952). After graduating in 1947, Flannery O'Connor pursued her...

Words: 710 - Pages: 3

Free Essay

Patient Education

...Systemic Lupus Erythematosus (SLE) is a complex disease that can affect many body systems. “Lupus is a chronic inflammatory autoimmune disease that can affect many parts of your body, including your skin, joints, kidneys, blood cells, heart and lungs” (Mayo Clinic, 2004, p.1). The diagnosis of Lupus evokes many questions and concerns in the patient. Educating patients is a major responsibility of nurses; therefore, the nurse should be knowledgeable in answering these questions. The nurse should be knowledgeable in answering these questions as educating patients is a major responsibility of nurses. Each patient is different; therefore, the education method should be individualized. You must take into consideration the patient’s motivation to learn and also the patient’s learning style. Motivation (or readiness) to learn must be determined in the early stages of developing a teaching plan. The more motivated the patient is to learn, the more cooperative and attentive they will be during the implementation of the teaching plan. Patients who participate in their own care are more likely to retain the information presented to them. When assessing the motivation of the patient, consider if the patient has asked questions about his or her condition. Asking questions shows that the patient has a desire or motivation to learn more about his or her condition. Does the patient appear interested in learning more about his or her disease? Has the patient accepted the diagnosis or is he......

Words: 1405 - Pages: 6

Premium Essay

Paper

...BIO483 Exam #4 Review Comprehensive and/or early Weeks Know all conditions that cause splenomegaly All associated diseases with EBV Week 1 Mechanisms of Cellular Adaptation Types of necrosis and pathology where most likely found. Apply the definitions of Atrophy, hypertrophy, hyperplasia, hypoplasia, dysplasia, and metaplasia. Week 2 Pain Throughout Organ Systems General anatomy of kidneys, appendix, gallbladder, pancreas, spleen, male and female reproductive organs. Costochondritis vs Angina Pectoris vs Myocardial Infarctions. Rheumatoid arthritis Gout lab findings Week 3 Fluid Balance and Edema Electrolyte imbalances of sodium, potassium, calcium, and magnesium. Intra and Extra cellular concentrations of sodium and potassium as related to osmotic balance. Know the physical signs/symptoms of electrolyte imbalances including hyper and hypo natremia, kalemia, and calcemia. SIADH lab and imaging findings Diabetes insipidus lab and imaging findings Week 4 Topic 4 Acidosis and Alkalosis Know your acid-bases! Week 5 Topic 5 Cardiovascular Causes of Fatigue Cor-pulmonale, cardiomyopathies Week 6 Topic 6 Thyroid, Adrenal, Liver Fatigue Hashimoto’s thyroiditis vs. DeQuervain vs. nodular goiter vs. secondary hypothyroidism Cirrhosis, Addison disease lab tests and hormone responsible. Is it high or low? Week 7 Topic 7 Bleeding as Indicator of Disease Pathophysiology of Disseminated Intravascular Coagulation Pathophysiology of......

Words: 1128 - Pages: 5

Free Essay

Mixed Connective Tissue Disease

...characteristics. These overlapping characteristics include the diseases systemic lupus erythematosus (SLE), systemic sclerosis, and polymyositis (http://lup.sagepub.com/content/15/3/132.short). Though the disease is somewhat unknown and presumably hereditary, the uncovered cause and criteria for diagnosis is linked through like antibodies and antigens (http://www.nejm.org/doi/pdf/10.1056/NEJM197611182952101). MCTD affects numerous body systems i.e. skeletal, muscular, skeletal, digestive, and nervous (https://my.clevelandclinic.org/health/diseases_conditions/hic_Mixed_Connective_Tissue_Disease). Treatment for this disease is patient specific depending on the severity of each case; while the medications prescribed are ailment specific, creating a huge risk of developing side effects due to contraindications and normal use. In diagnosing these side effects, one must first explore the history of MCTD. What is Mixed Connective Tissue Disease (MCTD)? In 1972 (Venables) Mixed Connective Tissue Disease (MCTD) was first recognized for its overlapping features by its like or “mixed” similarities noticed in patients presenting with signs and symptoms of three autoimmune connective tissue diseases. The like featured diseases that make up Mixed Connective Tissue Disease (MCTD) are systemic lupus erythematosus (SLE) (an autoimmune disease where healthy tissue is mistakenly attacked by the body’s immune system), systemic sclerosis (characterized as both an autoimmune and......

Words: 702 - Pages: 3

Free Essay

Lupus

...Systemic Lupus Erythematosus Abstract Systemic Lupus Erythematosus (SLE) is a systemic rheumatic autoimmune disease that affects multiple organ systems. The exact cause or causes of (SLE) is unknown, however genetic factors, gender, ethnic origin, and environmental factors have all been implicated in its development. Earlier diagnosis and more effective treatment options have significantly improved survival rates and life quality. Medical and pharmacologic treatment is usually tailored to the specific symptoms or organ systems that are involved due to its unpredictability and range of manifestations. Systemic Lupus Erythematosus affects primarily women of childbearing age and mostly in Asian, African American, and Hispanic populations. Treatment options include steroids, antimalarial drugs, and immunosuppressive agents. This overview will examine the etiology and effects of Lupus, how it impacts fertility and pregnancy in women, and life quality and expectancy. Various treatment options and alternative treatment methods will be discussed; considerations for employment and rehabilitation will be reviewed, as well as the future of therapeutic approaches. Systemic Lupus Erythematosus Introduction The name “Lupus” is Latin for wolf and may have first been used to describe the lesions that resembled the bite marks and scratches made by a wolf's attack. The term “Lupus Erythematosus” was first introduced by physicians in the nineteenth century to describe skin......

Words: 5355 - Pages: 22

Premium Essay

Lupus an Autoimmune Disease

...Lupus an Autoimmune Disease Human Body Professor E. December 2012 Abstract Systemic lupus erythematous (SLE) is a complex disease characterized by the appearance of autoantibodies against nuclear antigens and the involvement of multiple organ systems, including the kidneys. The exact events that trigger the onset of clinical manifestations of SLE are not yet well understood. However, research using various mouse strains impulsive and inducible lupus in the last two decades has provided insights into the role of the immune system in the pathogenesis of this disease. According to our present understanding, the immunological defects resulting in the development of SLE can be categorized into two phases: (a) systemic autoimmunity resulting in increased serum antinuclear and antiglomerular autoantibodies and (b) immunological events that occur within the target organ and result in end organ damage. TABLE OF CONTENT Abstract…………………………………………………………………….....2 Introduction…………………………………………………………………..4 Discussion……………………………………………………………………..5 What is lupus? Lupus is a chronic autoimmune disease, which causes inflammation of various parts of the body, especially the skin, joints and kidneys. The body’s immune system normally makes proteins called antibodies to protect the body against viruses, bacteria and other foreign materials. These foreign materials are called antigens. In an autoimmune disorder such as lupus, the immune system loses its ability to tell the......

Words: 1470 - Pages: 6

Free Essay

Lupus

...Abstract There are four types of lupus, systemic lupus erythematous, discoid, drug-induced, and neonatal lupus. Systemic lupus erythematous, also known as SLE or lupus and is sometimes called the “great imitator” due to the fact that it mnemonics so many other diseases. Family practice offices often misdiagnose lupus due to lack of symptoms at the time of visit, patients being poor historians and lab work that is inconclusive at that time. Discoid lupus affects only the skin and causes rashes and lesions mostly of the face, neck and scalp. During drug-induced lupus the person will experience lupus like symptoms. These symptoms usually resolve within six months after the drug is stopped. Individuals with drug- induced lupus may have a positive Antinuclear Antibody test more years after the episode. Neonatal lupus occurs when a child is born to a women with lupus. The infant may have lupus symptoms including rashes, anemia and liver problem which usually resolve within a few months. Some infants born to mothers with lupus may have serious heart defects. For the purpose of this paper the focus will be on systemic lupus erythematous. Systemic Lupus Erythematous Systemic lupus erythematous is a complex multisystem autoimmune disease in which the body’s immune system misfires and makes autoantibodies that attacks its own tissue. Lupus affects as many as 1.5 million people in America. (U.S. Department of Health and Human Services, 2007) Women are more commonly......

Words: 2199 - Pages: 9

Premium Essay

Health/Nutrition

...Ashwagandha Human Biology and Nutrition April 12, 2015 What is Ashwagandha? Ashwagandha also known as Indian winter cherry. Ashwagandha is a shrub cultivated in India and North America whose roots have been used for thousands of years by Ayurvedic practitioners in many medicinal ways. The root contains flavonoids and many active ingredients. Ashwagandha is most well-known for its restorative benefits. In Sanskrit Ashwagandha means “the smell of a horse,” indicating that the herb imparts the vigor and strength of a stallion, and has traditionally been prescribed to help people strengthen their immune system after an illness. I have never personally seen ashwagandha but it belongs to the same family as the tomato. Ashwagandha is a small shrub with oval leaves and yellow flowers. It produces red fruit about the size of a raisin. The herb is native to the dry regions of India, northern Africa, and the Middle East, and today is also grown in more mild climates, including the United States.The root and leaf are the parts that are used because they contain the highest amount of steroidal compounds which include the lactones Withaferin A, and carbon-27-glycowithanolides, known best as Withanolides Ashwagandha has been used as an herbal remedy for hundreds of years. It has many applications, and has been used to treat inflammation, fevers, and to protect against infection or illness. It has also been used to boost the immune system and improve memory. Ashwagandha is believed...

Words: 709 - Pages: 3

Premium Essay

Systemic Lupus Erythematosus Research Paper

...Systemic Lupus Erythematosus Systemic Lupus Erythematosus (SLE) is considered one of many immune system disorders(5). SLE is a chronic inflammatory disease that affects many parts of the body through an autoimmune process(2). A natural immune system creates antibodies to fight antigens which are harmful substances such as viruses and bacteria. Whereas in SLE, the immune system does not differentiate between the natural tissues of the body and the foreign particles(5)(6). Auto-antibodies are produced that mistakenly attack the immune system itself and cause inflammation and damage to various body tissues(6)(7). The disease course is marked by remissions and relapses and may vary from mild to severe. Just like many immune system disorders,...

Words: 566 - Pages: 3

Free Essay

Esa Resistance in Pediatric Ckd

...Hematology - CKD M’Lyn Spinks Combating anemia in chronic kidney disease (CKD) with erythropoietin-stimulating agents (ESAs) has been shown to improve both mental and physical factors (Iranian, 2013). Erythropoietin (EPO) is a protein hormone produced by the kidney that binds with receptors in the bone marrow and stimulates erythrocyte production (Munk, 2013). Perceptions of quality of life, cognition, sexual function, symptoms of depression and socialization are all scored higher in patients with Hb levels in near-normal range (Iranian, 2013). While the most common physical symptoms of anemia in CKD improve with ESA treatment, it is also been shown to positively effect the more severe consequences (Iranian, 2013). Improvement in cardiac function has been noted in patients diagnosed with left ventricular hypertrophy and congestive heart failure (Iran, 2013) as well as stabilized renal function in non-dialysis patients (Iranian, 2013). Treatment of anemia in CKD patients is also attributed to reducing lengths of hospital stays and decreasing mortality rates (Iranian, 2013). While the benefits of ESA’s in combating the symptoms and consequences of anemia in CKD are indisputable, there is a wide range of treatment regimens, inconsistent parameters for treatment, and increased risk of stroke and morbidity in the pediatric population (Bamgbola, 2011). Regimens have been reported that are up to 30% different in dose and results show wide variations in patient response......

Words: 445 - Pages: 2

Free Essay

How to Save American Colleges?

...[Name] [Professor] [Subject] [Date] How to save American colleges? One of the good thing about this article is that author has provided a thought provoking piece to the readers in the sense of mentioning details and sharing survey findings. Quoting the relevant executives along with mentioning surveys like Gallup-Purdue Index, writer keeps a flow of information that keeps generating interest. Latter he includes the reasons of spearheading survey findings by President of Purdue University who argues with logic and facts and provides sufficient data to support his position by giving economic tutorials. Article becomes theoretically boring as the writer starts talking about the corporate board and contingency planning for dealing financial challenges on part of educational institutes. For a reader outside the educational infrastructure, these challenges of finances are out of the box. They remain un-understandable. Although article ends up balancing with mentioning drawbacks of such detail insight as advocate faces critiques in response to his ideas. I like few interesting features of the article especially when writer talks about growth of students in the sense of measuring their learning process. He explains areas of critical thinking and writing to check and compare their learning growth from freshman year till commencement. He further exerts on his point by mentioning an earlier 2005 report which assures the same stance that four-year college graduates could not......

Words: 333 - Pages: 2

Free Essay

Matrix

...2012 NUR427 Laurie Baumgartner RN, MSN, CNS, NP, CCRN Introduction This paper will examine the chronic disease of lupus. A big portion of information in the paper comes from a patient Anna. The areas of her life that are affected by the disease , and the motivators for lifestyle change are discussed. The education of Anna regarding the disease and learning model theory will be examined. What is Lupus? Lupus is a chronic autoimmune disease. The immune system fights off invaders in the body. The body develops antibodies to protect from invaders. The immune system affected by lupus cannot tell the difference between good and bad tissue. This process causes the immune system to attack itself. There are many different types of lupus. The type Anna has is cutaneous and systemic. Cutaneous affects the skin. Systemic lupus in her case affects the joints. Cutaneous lupus causes skin rashes/lesions. The most familiar rash is the butterfly rash. The rash occurs on the bridge of the nose and across upper cheeks. Systemic lupus cause the joints become painful and inflamed. Anna The interview with Anna was held over a couple of days. Anna was diagnosed a year and a half ago with lupus. Anna believes that she has had the disease for longer than a year and a half. The rashes that she experienced had been occurring since she was 19. Anna is now 41 years old. Anna is married......

Words: 1722 - Pages: 7

Premium Essay

Autoimmune Diseases

...The immune system’s job is to protect the body against diseases and other invaders that the body recognizes as foreign. Because of the immune system, our bodies are able to fight off illnesses such as the common cold. What would happen if the immune system started to attack healthy cells within your body for no known reason? Unfortunately, that is what happens to individuals who suffer from an autoimmune disease. Autoimmune disease describes a group of diseases that can affect the human organ systems. These diseases all have the same underlying problem. Which is the body’s immune system becomes defective and attacks the organs in which it was supposed to protect (Autoimmune Disease in Women, 2013). The cause is still unknown as to why the immune system can no longer tell the difference between healthy body tissues and antigens, but it is believed some microorganism, different drugs, and certain genes may increase the risk of developing an autoimmune disease (Dugdale, 2011). Having an autoimmune disease can be difficult for a person, especially in the early stages, because many do not know what to expect or have the basic knowledge on the disease. For many, these diseases can cause major complications and illnesses, especially when going untreated for long periods of time. Fortunately, with the advances in medicine and research, people, with autoimmune diseases, can live long, normal lives with proper support and treatment. According to the Centers for Disease......

Words: 1984 - Pages: 8

Free Essay

Lupus Awareness

...​​​​ LUPUS AWARENESS ESSAY Throughout the world today there is an estimated amount of 5 million people who has a disease called lupus erythematosus. Lupus erythematosus can be a fatal disease to those who have it. As defined on several sites lupus erythematosus is a chronic autoimmune disease that can damage any part of the human body. Saying chronic simply means the symptoms may last longer than six weeks and often many times for years. Lupus is normally found in women of childbearing ages 15-44. There is not yet a cure for the disease. In this essay I will further discuss the diagnosis of lupus and its four branches. I will also be discussing the many symptoms of lupus and the treatments that are used to contain the disease. Now let’s look into how the disease is diagnosed. ​To start of with, lupus erythematosus is once again defined as a chronic autoimmune disease that can damage any part of your body. What this means is your body immune system cannot tell the difference between your bodies healthy tissues and the foreign invaders. So your body will then create autoantibodies that will attack and destroy your bodies healthy tissues. The autoaintibodies that is created will then cause inflammation, and pain. There are four branches of lupus erythematosus. (1) The first branch is systemic lupus erythematosus which is an inflammatory autoimmune disease that attacks nearly every organ in your body (skin, joints, brain, lungs, kidneys, blood, and central nervous......

Words: 806 - Pages: 4

Premium Essay

Lupus Fog Index of 7.9

...Lupus is a disease that makes a person’s body unable to tell what is healthy tissue and disease tissue. The body’s white blood cells respond by attacking the body’s own tissue which causes a person with lupus to have muscle aches and/or problems with their organs. People with lupus do not always feel the effects of the disease. When lupus patients feel well they are said to be in remission. However, when patients feel ill they are said to be having a flare. Lupus can affect all races, genders, and ages, but is most common in women between the ages of 15-40. There are three known types of lupus each being unique. Discoid lupus affects the skin, SLE affects the joints and organs. The last form, drug-induced, is a side effect caused by medications during a person’s time on a drug not a natural disease. As of today, the cause of lupus is unknown, but has been found to have a basis in genetics, hormones, and the environment in which the person is exposed. Lupus affects twenty in every one hundred thousand people across the globe. When a person with lupus has a flare they may feel tired, have joint pain, and suffer headaches. Other problems such as hair loss, low red blood cell count, and chest pains have also been reported. Most cases of lupus are usually in a person’s teenage years, but is not exclusive to this age group. Childhood cases tend to be more severe due to changes during the child’s growth. Lupus is hard to diagnose because there is no single test that says whether...

Words: 354 - Pages: 2