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Task 5

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Submitted By karenrd6
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Bovine Spongiform encephalopathy (BSE) occurs at a molecular level by infectious proteins also known as Prions. Prions can form by changes in DNA or mutations which result in a change of protein conformation. Chaperones provide an environment so proteins fold properly, bad chaperones influence the good chaperones to take form as harmful proteins. Eventually aggregates of these harmful proteins form and these aggregates lead to cell death. “The prion hypothesis suggest that diseases like BSE are caused by the misfolding of a protein known as PrP that most cells contain. Once a few copies of protein become misfolded they cause PrP’s to misfold, leading to accumulation of insoluble proteins in the cell. These misfolded proteins cause cell death and damage to the nervous system.”
A country without regulations in place can help reduce risk of transmitting BSE by properly discarding possibly contaminated cattle feed. Brain and spinal cord matter should be discarded, and watching cattle with possible signs of BSE should not be introduced into the feed. One possible sign of BSE in cattle is not being able to walk, some may demonstrate aggressive behavior. The following statement is another possible way of introducing safe ways to discard contaminated cattle in a country without regulations: “According to Dr. Lisa Ferguson, a senior staff veterinarian at the Agriculture Department, said the department favored dissolving carcasses in tissue digestors, are essentially giant pressure cookers heated to 300 Fahrenheit.” This process is said to destroy the prions and reducing the remains into liquid.

References

Retrieved from http://www.bseinfo.org/governmentregulations.aspx
Retrieved from wgu.thinkwell.com
Retrieved from http://www.millerandlevine.com/news/bse/
Retrieved from https://www.organicconsumers.org/old_articles/madcow/disposal1604.php

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